Mucin-1

"Mucin-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Carbohydrate antigen elevated in patients with tumors of the breast, ovary, lung, and prostate as well as other disorders. The mucin is expressed normally by most glandular epithelia but shows particularly increased expression in the breast at lactation and in malignancy. It is thus an established serum marker for breast cancer.

Descriptor ID	D018396
MeSH Number(s)	D12.776.395.550.560 D12.776.395.560.631.115 D12.776.543.550.530 D23.050.285.050.300 D23.050.550.325.300 D23.101.140.075.300
Concept/Terms	Mucin-1 Mucin-1 Mucin 1 CA 15.3 Antigen Antigen, CA 15.3 Antigen CA-15-3 Antigen CA 15 3 CA-15-3, Antigen CA-15-3 Antigen Antigen, CA-15-3 Episialin CD227 Antigen Antigen, CD227 Polymorphic Epithelial Mucin Epithelial Membrane Antigen Antigen, Epithelial Membrane Membrane Antigen, Epithelial Muc1 Mucin Mucin, Muc1 Antigens, CD227 CD227 Antigens CA 15-3 Antigen Antigen, CA 15-3 CA 15 3 Antigen Epithelial Mucin, Polymorphic Mucin, Polymorphic Epithelial

Below are MeSH descriptors whose meaning is more general than "Mucin-1".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Glycoproteins [D12.776.395]
Membrane Glycoproteins [D12.776.395.550]
Mucin-1 [D12.776.395.550.560]
Mucoproteins [D12.776.395.560]
Mucins [D12.776.395.560.631]
Mucin-1 [D12.776.395.560.631.115]
Membrane Proteins [D12.776.543]
Membrane Glycoproteins [D12.776.543.550]
Mucin-1 [D12.776.543.550.530]
Biological Factors [D23]
Antigens [D23.050]
Antigens, Neoplasm [D23.050.285]
Antigens, Tumor-Associated, Carbohydrate [D23.050.285.050]
Mucin-1 [D23.050.285.050.300]
Epitopes [D23.050.550]
Antigens, Tumor-Associated, Carbohydrate [D23.050.550.325]
Mucin-1 [D23.050.550.325.300]
Biomarkers [D23.101]
Biomarkers, Tumor [D23.101.140]
Antigens, Tumor-Associated, Carbohydrate [D23.101.140.075]
Mucin-1 [D23.101.140.075.300]

Below are MeSH descriptors whose meaning is related to "Mucin-1".

Below are MeSH descriptors whose meaning is more specific than "Mucin-1".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Mucin-1" by people in this website by year, and whether "Mucin-1" was a major or minor topic of these publications.

Bar chart showing 7 publications over 7 distinct years, with a maximum of 1 publications in 2003 and 2004 and 2012 and 2013 and 2018 and 2021 and 2022

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2003	1	0	1
2004	0	1	1
2012	1	0	1
2013	1	0	1
2018	1	0	1
2021	1	0	1
2022	0	1	1

Below are the most recent publications written about "Mucin-1" by people in Profiles.

Mehta A, Azam S, Rahmani A, Rizvi M, Mandal A. Expression of epithelial membrane antigen and cytokeratin among Indian workers exposed to cotton fibre dust in textile industries. East Mediterr Health J. 2022 Feb 27; 28(2):152-157.

View in: PubMed
Mohl JE, Gerken TA, Leung MY. ISOGlyP: de novo prediction of isoform-specific mucin-type O-glycosylation. Glycobiology. 2021 04 01; 31(3):168-172.

View in: PubMed
Rathinavelu A, Kanagasabai T, Dhandayuthapani S, Alhazzani K. Anti-angiogenic and pro-apoptotic effects of a small-molecule JFD-WS in in vitro and breast cancer xenograft mouse models. Oncol Rep. 2018 Apr; 39(4):1711-1724.

View in: PubMed
Raina D, Agarwal P, Lee J, Bharti A, McKnight CJ, Sharma P, Kharbanda S, Kufe D. Characterization of the MUC1-C Cytoplasmic Domain as a Cancer Target. PLoS One. 2015; 10(8):e0135156.

View in: PubMed
Kirby A, Gnirke A, Jaffe DB, Bare?ov? V, Pochet N, Blumenstiel B, Ye C, Aird D, Stevens C, Robinson JT, Cabili MN, Gat-Viks I, Kelliher E, Daza R, DeFelice M, Hulkov? H, Sovov? J, Vylet'al P, Antignac C, Guttman M, Handsaker RE, Perrin D, Steelman S, Sigurdsson S, Scheinman SJ, Sougnez C, Cibulskis K, Parkin M, Green T, Rossin E, Zody MC, Xavier RJ, Pollak MR, Alper SL, Lindblad-Toh K, Gabriel S, Hart PS, Regev A, Nusbaum C, Kmoch S, Bleyer AJ, Lander ES, Daly MJ. Mutations causing medullary cystic kidney disease type 1 lie in a large VNTR in MUC1 missed by massively parallel sequencing. Nat Genet. 2013 Mar; 45(3):299-303.

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Song W, Delyria ES, Chen J, Huang W, Lee JS, Mittendorf EA, Ibrahim N, Radvanyi LG, Li Y, Lu H, Xu H, Shi Y, Wang LX, Ross JA, Rodrigues SP, Almeida IC, Yang X, Qu J, Schocker NS, Michael K, Zhou D. MUC1 glycopeptide epitopes predicted by computational glycomics. Int J Oncol. 2012 Dec; 41(6):1977-84.

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Mitchell MS, Lund TA, Sewell AK, Marincola FM, Paul E, Schroder K, Wilson DB, Kan-Mitchell J. The cytotoxic T cell response to peptide analogs of the HLA-A*0201-restricted MUC1 signal sequence epitope, M1.2. Cancer Immunol Immunother. 2007 Mar; 56(3):287-301.

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Wang H, Lillehoj EP, Kim KC. MUC1 tyrosine phosphorylation activates the extracellular signal-regulated kinase. Biochem Biophys Res Commun. 2004 Aug 20; 321(2):448-54.

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Wang H, Lillehoj EP, Kim KC. Identification of four sites of stimulated tyrosine phosphorylation in the MUC1 cytoplasmic tail. Biochem Biophys Res Commun. 2003 Oct 17; 310(2):341-6.

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Reddish M, MacLean GD, Koganty RR, Kan-Mitchell J, Jones V, Mitchell MS, Longenecker BM. Anti-MUC1 class I restricted CTLs in metastatic breast cancer patients immunized with a synthetic MUC1 peptide. Int J Cancer. 1998 Jun 10; 76(6):817-23.

View in: PubMed

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