"GAP-43 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nervous tissue specific protein which is highly expressed in NEURONS during development and NERVE REGENERATION. It has been implicated in neurite outgrowth, long-term potentiation, SIGNAL TRANSDUCTION, and NEUROTRANSMITTER release. (From Neurotoxicology 1994;15(1):41-7) It is also a substrate of PROTEIN KINASE C.
| Descriptor ID |
D019922
|
| MeSH Number(s) |
D12.776.395.550.400 D12.776.543.550.400 D12.776.631.400
|
| Concept/Terms |
GAP-43 Protein- GAP-43 Protein
- GAP 43 Protein
- Phosphoprotein B-50
- Phosphoprotein B 50
- GAP-43
- Neuromodulin
- Growth-Associated Protein 43
- Growth Associated Protein 43
- Phosphoprotein pp46
- B-50 Protein
- B 50 Protein
- GAP43 Protein
- Nerve Growth Cone Membrane Protein GAP-43
- Nerve Growth Cone Membrane Protein GAP 43
- Phosphoprotein F1
|
Below are MeSH descriptors whose meaning is more general than "GAP-43 Protein".
Below are MeSH descriptors whose meaning is more specific than "GAP-43 Protein".
This graph shows the total number of publications written about "GAP-43 Protein" by people in this website by year, and whether "GAP-43 Protein" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 0 | 1 |
| 2002 | 1 | 0 | 1 |
| 2003 | 1 | 1 | 2 |
| 2004 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "GAP-43 Protein" by people in Profiles.
-
Williams S, Mmbaga N, Chirwa S. Dopaminergic D1 receptor agonist SKF 38393 induces GAP-43 expression and long-term potentiation in hippocampus in vivo. Neurosci Lett. 2006 Jul 10; 402(1-2):46-50.
-
Chirwa S, Aduonum A, Pizarro J, Reasor J, Kawai Y, Gonzalez M, McAdory BS, Onaivi E, Barea-Rodriguez EJ. Dopaminergic DA1 signaling couples growth-associated protein-43 and long-term potentiation in guinea pig hippocampus. Brain Res Bull. 2005 Jan 15; 64(5):433-40.
-
Willcox BJ, Scott JN. Growth-associated proteins and regeneration-induced gene expression in the aging neuron. Mech Ageing Dev. 2004 Jul; 125(7):513-6.
-
Soto I, Marie B, Baro DJ, Blanco RE. FGF-2 modulates expression and distribution of GAP-43 in frog retinal ganglion cells after optic nerve injury. J Neurosci Res. 2003 Aug 15; 73(4):507-17.
-
Liu YB, Wu CC, Lu LS, Su MJ, Lin CW, Lin SF, Chen LS, Fishbein MC, Chen PS, Lee YT. Sympathetic nerve sprouting, electrical remodeling, and increased vulnerability to ventricular fibrillation in hypercholesterolemic rabbits. Circ Res. 2003 May 30; 92(10):1145-52.
-
Ferrini M, Bisagno V, Piroli G, Grillo C, Gonz?lez Deniselle MC, De Nicola AF. Effects of estrogens on choline-acetyltransferase immunoreactivity and GAP-43 mRNA in the forebrain of young and aging male rats. Cell Mol Neurobiol. 2002 Jun; 22(3):289-301.
-
Routtenberg A, Cantallops I, Zaffuto S, Serrano P, Namgung U. Enhanced learning after genetic overexpression of a brain growth protein. Proc Natl Acad Sci U S A. 2000 Jun 20; 97(13):7657-62.