Fragile X Mental Retardation Protein

"Fragile X Mental Retardation Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A RNA-binding protein that is found predominately in the CYTOPLASM. It helps regulate GENETIC TRANSLATION in NEURONS and is absent or under-expressed in FRAGILE X SYNDROME.

Descriptor ID	D051860
MeSH Number(s)	D12.776.157.725.061 D12.776.631.299 D12.776.664.962.124
Concept/Terms	Fragile X Mental Retardation Protein Fragile X Mental Retardation Protein FMRP Protein Fragile X Mental Retardation-1 Protein Fragile X Mental Retardation 1 Protein

Below are MeSH descriptors whose meaning is more general than "Fragile X Mental Retardation Protein".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Carrier Proteins [D12.776.157]
RNA-Binding Proteins [D12.776.157.725]
Fragile X Mental Retardation Protein [D12.776.157.725.061]
Nerve Tissue Proteins [D12.776.631]
Fragile X Mental Retardation Protein [D12.776.631.299]
Nucleoproteins [D12.776.664]
RNA-Binding Proteins [D12.776.664.962]
Fragile X Mental Retardation Protein [D12.776.664.962.124]

Below are MeSH descriptors whose meaning is related to "Fragile X Mental Retardation Protein".

Below are MeSH descriptors whose meaning is more specific than "Fragile X Mental Retardation Protein".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Fragile X Mental Retardation Protein" by people in this website by year, and whether "Fragile X Mental Retardation Protein" was a major or minor topic of these publications.

Bar chart showing 6 publications over 6 distinct years, with a maximum of 1 publications in 2006 and 2010 and 2012 and 2014 and 2016 and 2022

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2006	1	0	1
2010	1	0	1
2012	1	0	1
2014	0	1	1
2016	0	1	1
2022	0	1	1

Below are the most recent publications written about "Fragile X Mental Retardation Protein" by people in Profiles.

Enguita FJ, Leit?o AL, McDonald JT, Zaksas V, Das S, Galeano D, Taylor D, Wurtele ES, Saravia-Butler A, Baylin SB, Meller R, Porterfield DM, Wallace DC, Schisler JC, Mason CE, Beheshti A. The interplay between lncRNAs, RNA-binding proteins and viral genome during SARS-CoV-2 infection reveals strong connections with regulatory events involved in RNA metabolism and immune response. Theranostics. 2022; 12(8):3946-3962.

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Conca Dioguardi C, Uslu B, Haynes M, Kurus M, Gul M, Miao DQ, De Santis L, Ferrari M, Bellone S, Santin A, Giulivi C, Hoffman G, Usdin K, Johnson J. Granulosa cell and oocyte mitochondrial abnormalities in a mouse model of fragile X primary ovarian insufficiency. Mol Hum Reprod. 2016 06; 22(6):384-96.

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Alpatov R, Lesch BJ, Nakamoto-Kinoshita M, Blanco A, Chen S, St?tzer A, Armache KJ, Simon MD, Xu C, Ali M, Murn J, Prisic S, Kutateladze TG, Vakoc CR, Min J, Kingston RE, Fischle W, Warren ST, Page DC, Shi Y. A chromatin-dependent role of the fragile X mental retardation protein FMRP in the DNA damage response. Cell. 2014 May 08; 157(4):869-81.

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Hoffman GE, Le WW, Entezam A, Otsuka N, Tong ZB, Nelson L, Flaws JA, McDonald JH, Jafar S, Usdin K. Ovarian abnormalities in a mouse model of fragile X primary ovarian insufficiency. J Histochem Cytochem. 2012 Jun; 60(6):439-56.

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Adams-Cioaba MA, Guo Y, Bian C, Amaya MF, Lam R, Wasney GA, Vedadi M, Xu C, Min J. Structural studies of the tandem Tudor domains of fragile X mental retardation related proteins FXR1 and FXR2. PLoS One. 2010 Nov 02; 5(11):e13559.

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Yun SW, Platholi J, Flaherty MS, Fu W, Kottmann AH, Toth M. Fmrp is required for the establishment of the startle response during the critical period of auditory development. Brain Res. 2006 Sep 19; 1110(1):159-65.

View in: PubMed

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