"Gene Products, rev" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Trans-acting nuclear proteins whose functional expression are required for retroviral replication. Specifically, the rev gene products are required for processing and translation of the gag and env mRNAs, and thus rev regulates the expression of the viral structural proteins. rev can also regulate viral regulatory proteins. A cis-acting antirepression sequence (CAR) in env, also known as the rev-responsive element (RRE), is responsive to the rev gene product. rev is short for regulator of virion.
| Descriptor ID |
D015694
|
| MeSH Number(s) |
D12.776.157.725.076 D12.776.664.962.186 D12.776.964.925.984.385
|
| Concept/Terms |
Gene Products, rev- Gene Products, rev
- rev Gene Products
- rev Protein
- Gene Product, rev
- rev Gene Product
|
Below are MeSH descriptors whose meaning is more general than "Gene Products, rev".
Below are MeSH descriptors whose meaning is more specific than "Gene Products, rev".
This graph shows the total number of publications written about "Gene Products, rev" by people in this website by year, and whether "Gene Products, rev" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 |
| 2004 | 1 | 1 | 2 |
| 2006 | 0 | 1 | 1 |
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Below are the most recent publications written about "Gene Products, rev" by people in Profiles.
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Nekhai S, Jeang KT. Transcriptional and post-transcriptional regulation of HIV-1 gene expression: role of cellular factors for Tat and Rev. Future Microbiol. 2006 Dec; 1(4):417-26.
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Thompson ME, Robinson-Benion CL, Holt JT. An amino-terminal motif functions as a second nuclear export sequence in BRCA1. J Biol Chem. 2005 Jun 10; 280(23):21854-7.
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Llano M, Vanegas M, Fregoso O, Saenz D, Chung S, Peretz M, Poeschla EM. LEDGF/p75 determines cellular trafficking of diverse lentiviral but not murine oncoretroviral integrase proteins and is a component of functional lentiviral preintegration complexes. J Virol. 2004 Sep; 78(17):9524-37.
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Nguyen KL, llano M, Akari H, Miyagi E, Poeschla EM, Strebel K, Bour S. Codon optimization of the HIV-1 vpu and vif genes stabilizes their mRNA and allows for highly efficient Rev-independent expression. Virology. 2004 Feb 20; 319(2):163-75.
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Bond VC, Huang MB, Person B, Hairston R, Ye XY, Saltarelli M. Effects of the human immunodeficiency virus type 1 Rev protein on reporter gene and host T-cell gene expression. Cell Mol Biol (Noisy-le-grand). 1997 Nov; 43(7):995-1005.