Fibronectins

"Fibronectins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Glycoproteins found on the surfaces of cells, particularly in fibrillar structures. The proteins are lost or reduced when these cells undergo viral or chemical transformation. They are highly susceptible to proteolysis and are substrates for activated blood coagulation factor VIII. The forms present in plasma are called cold-insoluble globulins.

Descriptor ID	D005353
MeSH Number(s)	D12.776.377.715.390 D12.776.395.550.350 D12.776.543.550.350 D12.776.860.300.450
Concept/Terms	Fibronectins Fibronectins Opsonic alpha(2)SB Glycoprotein Opsonic Glycoprotein Glycoprotein, Opsonic LETS Proteins Proteins, LETS alpha 2-Surface Binding Glycoprotein alpha 2 Surface Binding Glycoprotein Fibronectin Cold-Insoluble Globulins Cold Insoluble Globulins Globulins, Cold-Insoluble

Below are MeSH descriptors whose meaning is more general than "Fibronectins".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Globulins [D12.776.377]
Serum Globulins [D12.776.377.715]
Fibronectins [D12.776.377.715.390]
Glycoproteins [D12.776.395]
Membrane Glycoproteins [D12.776.395.550]
Fibronectins [D12.776.395.550.350]
Membrane Proteins [D12.776.543]
Membrane Glycoproteins [D12.776.543.550]
Fibronectins [D12.776.543.550.350]
Scleroproteins [D12.776.860]
Extracellular Matrix Proteins [D12.776.860.300]
Fibronectins [D12.776.860.300.450]

Below are MeSH descriptors whose meaning is related to "Fibronectins".

Below are MeSH descriptors whose meaning is more specific than "Fibronectins".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Fibronectins" by people in this website by year, and whether "Fibronectins" was a major or minor topic of these publications.

Bar chart showing 49 publications over 24 distinct years, with a maximum of 4 publications in 2005 and 2011 and 2012 and 2017

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	1	0	1
1996	3	0	3
1997	1	0	1
1998	1	1	2
2000	0	1	1
2001	0	1	1
2002	0	2	2
2003	0	2	2
2005	1	3	4
2006	0	2	2
2007	0	1	1
2008	1	2	3
2009	0	2	2
2010	1	1	2
2011	0	4	4
2012	2	2	4
2013	0	1	1
2014	0	1	1
2015	0	2	2
2016	1	0	1
2017	1	3	4
2019	1	0	1
2020	2	0	2
2021	1	1	2

Below are the most recent publications written about "Fibronectins" by people in Profiles.

Pervin S, Reddy ST, Singh R. Novel Roles of Follistatin/Myostatin in Transforming Growth Factor-? Signaling and Adipose Browning: Potential for Therapeutic Intervention in Obesity Related Metabolic Disorders. Front Endocrinol (Lausanne). 2021; 12:653179.

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Magdaleno C, House T, Pawar JS, Carvalho S, Rajasekaran N, Varadaraj A. Fibronectin assembly regulates lumen formation in breast acini. J Cell Biochem. 2021 05; 122(5):524-537.

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Magdaleno C, Dixon L, Rajasekaran N, Varadaraj A. HIFa independent mechanisms in renal carcinoma cells modulate divergent outcomes in fibronectin assembly mediated by hypoxia and CoCl2. Sci Rep. 2020 10 29; 10(1):18560.

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Huaman J, Ogunwobi OO. Circulating Tumor Cell Migration Requires Fibronectin Acting through Integrin B1 or SLUG. Cells. 2020 07 01; 9(7).

View in: PubMed
Huaman J, Naidoo M, Zang X, Ogunwobi OO. Fibronectin Regulation of Integrin B1 and SLUG in Circulating Tumor Cells. Cells. 2019 06 20; 8(6).

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Igietseme JU, Omosun Y, Nagy T, Stuchlik O, Reed MS, He Q, Partin J, Joseph K, Ellerson D, George Z, Goldstein J, Eko FO, Bandea C, Pohl J, Black CM. Molecular Pathogenesis of Chlamydia Disease Complications: Epithelial-Mesenchymal Transition and Fibrosis. Infect Immun. 2018 01; 86(1).

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Pervin S, Singh V, Tucker A, Collazo J, Singh R. Modulation of transforming growth factor-?/follistatin signaling and white adipose browning: therapeutic implications for obesity related disorders. Horm Mol Biol Clin Investig. 2017 Sep 09; 31(2).

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Liu HF, Liu H, Lv LL, Ma KL, Wen Y, Chen L, Liu BC. CCN3 suppresses TGF-?1-induced extracellular matrix accumulation in human mesangial cells in vitro. Acta Pharmacol Sin. 2018 Feb; 39(2):222-229.

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Varadaraj A, Jenkins LM, Singh P, Chanda A, Snider J, Lee NY, Amsalem-Zafran AR, Ehrlich M, Henis YI, Mythreye K. TGF-? triggers rapid fibrillogenesis via a novel T?RII-dependent fibronectin-trafficking mechanism. Mol Biol Cell. 2017 May 01; 28(9):1195-1207.

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Das DK, Naidoo M, Ilboudo A, Park JY, Ali T, Krampis K, Robinson BD, Osborne JR, Ogunwobi OO. miR-1207-3p regulates the androgen receptor in prostate cancer via FNDC1/fibronectin. Exp Cell Res. 2016 Nov 01; 348(2):190-200.

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