Extracellular Matrix

"Extracellular Matrix" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A meshwork-like substance found within the extracellular space and in association with the basement membrane of the cell surface. It promotes cellular proliferation and provides a supporting structure to which cells or cell lysates in culture dishes adhere.

Descriptor ID	D005109
MeSH Number(s)	A11.284.295.310
Concept/Terms	Extracellular Matrix Extracellular Matrix Matrix, Extracellular Extracellular Matrices Matrices, Extracellular

Below are MeSH descriptors whose meaning is more general than "Extracellular Matrix".

Anatomy [A]
Cells [A11]
Cellular Structures [A11.284]
Extracellular Space [A11.284.295]
Extracellular Matrix [A11.284.295.310]

Below are MeSH descriptors whose meaning is related to "Extracellular Matrix".

Below are MeSH descriptors whose meaning is more specific than "Extracellular Matrix".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Extracellular Matrix" by people in this website by year, and whether "Extracellular Matrix" was a major or minor topic of these publications.

Bar chart showing 102 publications over 28 distinct years, with a maximum of 7 publications in 2006 and 2009 and 2012 and 2013 and 2019

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	0	1	1
1997	1	1	2
1998	0	1	1
2000	1	0	1
2002	1	3	4
2003	2	2	4
2004	3	1	4
2005	0	4	4
2006	3	4	7
2007	1	3	4
2008	1	3	4
2009	2	5	7
2010	1	0	1
2011	1	1	2
2012	3	4	7
2013	3	4	7
2014	2	3	5
2015	0	1	1
2016	2	1	3
2017	1	3	4
2018	3	2	5
2019	2	5	7
2020	2	3	5
2021	2	3	5
2022	0	2	2
2023	1	1	2
2024	2	0	2
2025	0	1	1

Below are the most recent publications written about "Extracellular Matrix" by people in Profiles.

Moschini G, Mohanan AG, Niewczas IS, Taylor DE, Jaeger PK, Turiel G, Hussien AA, Wunderli SL, Baumberger O, Wolleb M, Marti F, Niederoest B, Bollhalder M, Ardicoglu R, Tisch N, Masschelein E, Loopmans S, Morice S, Ardiles S, Mous L, Ghesqui?re B, Aronoff MR, Hilbe M, Selman F, Wieser K, Fucentese SF, Passini FS, Blache U, Surdez D, Wennemers H, Elewaut D, Clark J, De Bock K, Snedeker JG. HIF1a gates tendon response to overload and drives tendinopathy independently of vascular recruitment. Sci Transl Med. 2026 Jan 07; 18(831):eadt1228.

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Barajas J, Yang Z, Agyare E, Zhu X, Yoon SJ, Han B. Matrix stiffness influences drug resistance to gemcitabine analog and AZD 1775 combination in PDAC organoids. PLoS One. 2025; 20(12):e0326550.

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Shin HE, An S, Heckl J, Komori C, Sullivan H, Zorilla R, Yoon H, Pedro TK, Tallquist MD, Park J. PDGFRa+ fibroblast ablation exacerbates pathologic features in a model of house dust mite-induced allergenic asthma. Dis Model Mech. 2025 12 01; 18(12).

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Sasuclark AR, Watanabe M, Roshto K, Kilonzo VW, Zhang Y, Pitts MW. Selenium deficiency impedes maturation of parvalbumin interneurons, perineuronal nets, and neural network activity. Redox Biol. 2025 04; 81:103548.

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Magdaleno C, Tschumperlin DJ, Rajasekaran N, Varadaraj A. SOCS domain targets ECM assembly in lung fibroblasts and experimental lung fibrosis. Sci Rep. 2024 12 30; 14(1):31855.

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Waters JA, Robinson M, Lujano-Olazaba O, Lucht C, Gilbert SF, House CD. Omental Preadipocytes Stimulate Matrix Remodeling and IGF Signaling to Support Ovarian Cancer Metastasis. Cancer Res. 2024 Jul 02; 84(13):2073-2089.

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Markey MW, Pena CD, Venkatesh T, Cai L, Vazquez M. Retinal Progenitor Cells Exhibit Cadherin-Dependent Chemotaxis across Transplantable Extracellular Matrix of In Vitro Developmental and Adult Models. J Tissue Eng Regen Med. 2023; 2023:1381620.

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Aboukhater D, Morad B, Nasrallah N, Nasser SA, Sahebkar A, Kobeissy F, Boudaka A, Eid AH. Inflammation and hypertension: Underlying mechanisms and emerging understandings. J Cell Physiol. 2023 06; 238(6):1148-1159.

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Kuwabara JT, Hara A, Heckl JR, Pe?a B, Bhutada S, DeMaris R, Ivey MJ, DeAngelo LP, Liu X, Park J, Jahansooz JR, Mestroni L, McKinsey TA, Apte SS, Tallquist MD. Regulation of extracellular matrix composition by fibroblasts during perinatal cardiac maturation. J Mol Cell Cardiol. 2022 08; 169:84-95.

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Xu Y, Kirchner M. Segment-Long-Spacing (SLS) and the Polymorphic Structures of Fibrillar Collagen. Subcell Biochem. 2022; 99:495-521.

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