Glomerular Basement Membrane
"Glomerular Basement Membrane" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The layer of EXTRACELLULAR MATRIX that lies between the ENDOTHELIUM of the glomerular capillaries and the PODOCYTES of the inner or visceral layer of the BOWMAN CAPSULE. It is the product of these two cell types. It acts as a physical barrier and an ion-selective filter.
| Descriptor ID |
D050533
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| MeSH Number(s) |
A05.810.453.324.359.372.400 A05.810.453.736.520.224 A10.615.179.625 A11.284.295.310.279
|
| Concept/Terms |
Glomerular Basement Membrane- Glomerular Basement Membrane
- Basement Membrane, Glomerular
- Basement Membranes, Glomerular
- Glomerular Basement Membranes
- Membrane, Glomerular Basement
- Membranes, Glomerular Basement
|
Below are MeSH descriptors whose meaning is more general than "Glomerular Basement Membrane".
Below are MeSH descriptors whose meaning is more specific than "Glomerular Basement Membrane".
This graph shows the total number of publications written about "Glomerular Basement Membrane" by people in this website by year, and whether "Glomerular Basement Membrane" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2010 | 1 | 2 | 3 |
| 2016 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Glomerular Basement Membrane" by people in Profiles.
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Singh D, Oudit O, Hajtovic S, Sarbaugh D, Salis R, Adebowale T, James J, Spatz LA. Antibodies to an Epstein Barr Virus protein that cross-react with dsDNA have pathogenic potential. Mol Immunol. 2021 04; 132:41-52.
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Abrahamson DR, Steenhard BM, Stroganova L, Zelenchuk A, St John PL, Petroff MG, Patarroyo M, Borza DB. Maternal alloimmune IgG causes anti-glomerular basement membrane disease in perinatal transgenic mice that express human laminin a5. Kidney Int. 2019 12; 96(6):1320-1331.
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Borza DB. Glomerular basement membrane heparan sulfate in health and disease: A regulator of local complement activation. Matrix Biol. 2017 01; 57-58:299-310.
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Becknell B, Zender GA, Houston R, Baker PB, McBride KL, Luo W, Hains DS, Borza DB, Schwaderer AL. Novel X-linked glomerulopathy is associated with a COL4A5 missense mutation in a non-collagenous interruption. Kidney Int. 2011 Jan; 79(1):120-7.
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Pedchenko V, Bondar O, Fogo AB, Vanacore R, Voziyan P, Kitching AR, Wieslander J, Kashtan C, Borza DB, Neilson EG, Wilson CB, Hudson BG. Molecular architecture of the Goodpasture autoantigen in anti-GBM nephritis. N Engl J Med. 2010 Jul 22; 363(4):343-54.
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Yousefipour Z, Oyekan A, Newaz M. Interaction of oxidative stress, nitric oxide and peroxisome proliferator activated receptor gamma in acute renal failure. Pharmacol Ther. 2010 Mar; 125(3):436-45.
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Borza DB. Autoepitopes and alloepitopes of type IV collagen: role in the molecular pathogenesis of anti-GBM antibody glomerulonephritis. Nephron Exp Nephrol. 2007; 106(2):e37-43.
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Kang JS, Wang XP, Miner JH, Morello R, Sado Y, Abrahamson DR, Borza DB. Loss of alpha3/alpha4(IV) collagen from the glomerular basement membrane induces a strain-dependent isoform switch to alpha5alpha6(IV) collagen associated with longer renal survival in Col4a3-/- Alport mice. J Am Soc Nephrol. 2006 Jul; 17(7):1962-9.