"Nitroreductases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes which reduce nitro groups (NITRO COMPOUNDS) and other nitrogenous compounds.
| Descriptor ID |
D009601
|
| MeSH Number(s) |
D08.811.682.655
|
| Concept/Terms |
Nitroreductases- Nitroreductases
- Oxidoreductases Acting on other Nitrogenous Compounds as Donors
|
Below are MeSH descriptors whose meaning is more general than "Nitroreductases".
Below are MeSH descriptors whose meaning is more specific than "Nitroreductases".
This graph shows the total number of publications written about "Nitroreductases" by people in this website by year, and whether "Nitroreductases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 2 | 0 | 2 |
| 2001 | 2 | 0 | 2 |
| 2002 | 2 | 0 | 2 |
| 2012 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Nitroreductases" by people in Profiles.
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Sviatenko LK, Gorb L, Leszczynski J. NTO Degradation by Nitroreductase: A DFT Study. J Phys Chem B. 2022 08 18; 126(32):5991-6006.
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Chen J, Rosen BP. The Pseudomonas putida NfnB nitroreductase confers resistance to roxarsone. Sci Total Environ. 2020 Dec 15; 748:141339.
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Pitsawong W, Haynes CA, Koder RL, Rodgers DW, Miller AF. Mechanism-Informed Refinement Reveals Altered Substrate-Binding Mode for Catalytically Competent Nitroreductase. Structure. 2017 07 05; 25(7):978-987.e4.
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Isayev O, Crespo-Hern?ndez CE, Gorb L, Hill FC, Leszczynski J. In silico structure-function analysis of E. cloacae nitroreductase. Proteins. 2012 Dec; 80(12):2728-41.
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Koder RL, Haynes CA, Rodgers ME, Rodgers DW, Miller AF. Flavin thermodynamics explain the oxygen insensitivity of enteric nitroreductases. Biochemistry. 2002 Dec 03; 41(48):14197-205.
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Haynes CA, Koder RL, Miller AF, Rodgers DW. Structures of nitroreductase in three states: effects of inhibitor binding and reduction. J Biol Chem. 2002 Mar 29; 277(13):11513-20.
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Koder RL, Oyedele O, Miller AF. Retro-nitroreductase, a putative evolutionary precursor to Enterobacter cloacae strain 96-3 nitroreductase. Antioxid Redox Signal. 2001 Oct; 3(5):747-55.
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Nivinskas H, Koder RL, Anusevicius Z, Sarlauskas J, Miller AF, Cenas N. Quantitative structure-activity relationships in two-electron reduction of nitroaromatic compounds by Enterobacter cloacae NAD(P)H:nitroreductase. Arch Biochem Biophys. 2001 Jan 01; 385(1):170-8.
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Koder RL, Miller AF. Steady-state kinetic mechanism, stereospecificity, substrate and inhibitor specificity of Enterobacter cloacae nitroreductase. Biochim Biophys Acta. 1998 Sep 08; 1387(1-2):395-405.
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Koder RL, Miller AF. Overexpression, isotopic labeling, and spectral characterization of Enterobacter cloacae nitroreductase. Protein Expr Purif. 1998 Jun; 13(1):53-60.