Below are the most recent publications written about "Anti-Glomerular Basement Membrane Disease" by people in Profiles.
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Kuang H, Wang BN, Jia XY, Cui Z, Yu XJ, Jiang N, Borza DB, Zhao MH. Perlecan is a novel target of autoantibodies in anti-glomerular basement membrane disease. Nephrol Dial Transplant. 2025 Dec 23; 41(1):55-66.
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Kuang H, Shen CR, Jia XY, Tan M, Yang XF, Cui Z, Borza DB, Zhao MH. Autoantibodies against laminin-521 are pathogenic in anti-glomerular basement membrane disease. Kidney Int. 2023 12; 104(6):1124-1134.
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Borza DB, Manral P. Endopeptidase Therapy for Anti-Glomerular Basement Membrane Disease: Beware of Anti-Hinge Antibodies! J Am Soc Nephrol. 2022 10; 33(10):1953-1954.
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Shen CR, Jia XY, Luo W, Olaru F, Cui Z, Zhao MH, Borza DB. Laminin-521 is a Novel Target of Autoantibodies Associated with Lung Hemorrhage in Anti-GBM Disease. J Am Soc Nephrol. 2021 08; 32(8):1887-1897.
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Pokidysheva EN, Seeger H, Pedchenko V, Chetyrkin S, Bergmann C, Abrahamson D, Cui ZW, Delpire E, Fervenza FC, Fidler AL, Fogo AB, Gaspert A, Grohmann M, Gross O, Haddad G, Harris RC, Kashtan C, Kitching AR, Lorenzen JM, McAdoo S, Pusey CD, Segelmark M, Simmons A, Voziyan PA, Wagner T, W?thrich RP, Zhao MH, Boudko SP, Kistler AD, Hudson BG. Collagen IVa345 dysfunction in glomerular basement membrane diseases. I. Discovery of a COL4A3 variant in familial Goodpasture's and Alport diseases. J Biol Chem. 2021 Jan-Jun; 296:100590.
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Abrahamson DR, Steenhard BM, Stroganova L, Zelenchuk A, St John PL, Petroff MG, Patarroyo M, Borza DB. Maternal alloimmune IgG causes anti-glomerular basement membrane disease in perinatal transgenic mice that express human laminin a5. Kidney Int. 2019 12; 96(6):1320-1331.
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Borza DB. IgG4-restricted anti-glomerular basement membrane autoantibodies targeting quaternary epitopes of native a345(IV) collagen. Am J Kidney Dis. 2014 Jul; 64(1):156-7.
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Olaru F, Luo W, Suleiman H, St John PL, Ge L, Mezo AR, Shaw AS, Abrahamson DR, Miner JH, Borza DB. Neonatal Fc receptor promotes immune complex-mediated glomerular disease. J Am Soc Nephrol. 2014 May; 25(5):918-25.
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Olaru F, Luo W, Wang XP, Ge L, Hertz JM, Kashtan CE, Sado Y, Segal Y, Hudson BG, Borza DB. Quaternary epitopes of a345(IV) collagen initiate Alport post-transplant anti-GBM nephritis. J Am Soc Nephrol. 2013 May; 24(6):889-95.
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Olaru F, Wang XP, Luo W, Ge L, Miner JH, Kleinau S, Geiger XJ, Wasiluk A, Heidet L, Kitching AR, Borza DB. Proteolysis breaks tolerance toward intact a345(IV) collagen, eliciting novel anti-glomerular basement membrane autoantibodies specific for a345NC1 hexamers. J Immunol. 2013 Feb 15; 190(4):1424-32.