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Dorin-Bogdan Borza

TitlePhD
Faculty RankAssistant Professor
InstitutionMeharry Medical College
DepartmentMicrobiology, Immunology, & Physiology
AddressMeharry Medical College
4115 West Basic Sciences Bldg
1005 Dr. D.B.Todd, Jr. Blvd
Nashville TN 37208
Phone6159632833
ORCID ORCID Icon0000-0003-4568-279X Additional info
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    Collapse Overview 
    Collapse overview
    My research leverages my multi-disciplinary training in biochemistry, immunology and nephrology to elucidate the molecular mechanisms underlying the etiology and pathogenesis of antibody-mediated glomerular diseases. I have extensive experience and expertise studying the structure, function and pathobiology of type IV collagen and its role in acquired and inherited diseases of the glomerular basement membrane (GBM). I rank among the leading experts in the areas of Goodpasture disease (anti-GBM antibody nephritis) and Alport syndrome. I am also interested in the pathomechanisms of and factors contributing to health disparities in lupus nephritis and membranous nephropathy.

    Collapse Research 
    Collapse research activities and funding
    R21AI069874     (BORZA, DORIN-BOGDAN)Aug 1, 2006 - Jul 31, 2009
    NIH
    Age-related structural alterations in loss of self-tolerance to a3(IV) collagen
    Role: Principal Investigator
    R01DK080799     (BORZA, DORIN-BOGDAN)Sep 1, 2008 - Jun 30, 2014
    NIH
    Molecular pathogenesis of anti-glomerular basement membrane nephritis
    Role: Principal Investigator
    R21HL168484     (BORZA, DORIN-BOGDAN)Feb 1, 2023 - Jan 31, 2025
    NIH
    PLA2R1 Loss-of-Function: A Monogenic Cause of Sarcoidosis in African-Americans in the ACCESS Cohort
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Kuang H, Shen CR, Jia XY, Tan M, Yang XF, Cui Z, Borza DB, Zhao MH. Autoantibodies against laminin-521 are pathogenic in anti-glomerular basement membrane disease. Kidney Int. 2023 12; 104(6):1124-1134. PMID: 37598856.
      Citations:    Fields:    Translation:HumansAnimals
    2. Borza DB, Abrahamson DR, Gross O, Savige J. Editorial: Collagen IV nephropathies: Alport syndrome and beyond. Front Med (Lausanne). 2022; 9:1039949. PMID: 36250080.
      Citations:    
    3. Borza DB, Manral P. Endopeptidase Therapy for Anti-Glomerular Basement Membrane Disease: Beware of Anti-Hinge Antibodies! J Am Soc Nephrol. 2022 10; 33(10):1953-1954. PMID: 35948435.
      Citations:    Fields:    Translation:HumansCells
    4. Manral P, Caza TN, Storey AJ, Beck LH, Borza DB. The Alternative Pathway Is Necessary and Sufficient for Complement Activation by Anti-THSD7A Autoantibodies, Which Are Predominantly IgG4 in Membranous Nephropathy. Front Immunol. 2022; 13:952235. PMID: 35874690.
      Citations: 8     Fields:    Translation:Humans
    5. Borza DB. Fumarate in membranous nephropathy: more questions than answers. Kidney Int. 2021 09; 100(3):707. PMID: 34420662.
      Citations:    Fields:    Translation:Humans
    6. Shen CR, Jia XY, Luo W, Olaru F, Cui Z, Zhao MH, Borza DB. Laminin-521 is a Novel Target of Autoantibodies Associated with Lung Hemorrhage in Anti-GBM Disease. J Am Soc Nephrol. 2021 08; 32(8):1887-1897. PMID: 33893224.
      Citations: 3     Fields:    Translation:HumansAnimals
    7. Odiatis C, Savva I, Pieri M, Ioannou P, Petrou P, Papagregoriou G, Antoniadou K, Makrides N, Stefanou C, Ljubanovic DG, Nikolaou G, Borza DB, Stylianou K, Gross O, Deltas C. A glycine substitution in the collagenous domain of Col4a3 in mice recapitulates late onset Alport syndrome. Matrix Biol Plus. 2021 Feb; 9:100053. PMID: 33718859.
      Citations:    
    8. Abrahamson DR, Steenhard BM, Stroganova L, Zelenchuk A, St John PL, Petroff MG, Patarroyo M, Borza DB. Maternal alloimmune IgG causes anti-glomerular basement membrane disease in perinatal transgenic mice that express human laminin a5. Kidney Int. 2019 12; 96(6):1320-1331. PMID: 31530475.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    9. Manral P, Colon S, Bhave G, Zhao MH, Jain S, Borza DB. Peroxidasin Is a Novel Target of Autoantibodies in Lupus Nephritis. Kidney Int Rep. 2019 Jul; 4(7):1004-1006. PMID: 31317122.
      Citations:    
    10. Luo W, Olaru F, Miner JH, Beck LH, van der Vlag J, Thurman JM, Borza DB. Alternative Pathway Is Essential for Glomerular Complement Activation and Proteinuria in a Mouse Model of Membranous Nephropathy. Front Immunol. 2018; 9:1433. PMID: 29988342.
      Citations: 26     Fields:    
    11. Borza DB. Glomerular basement membrane heparan sulfate in health and disease: A regulator of local complement activation. Matrix Biol. 2017 01; 57-58:299-310. PMID: 27609404.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    12. Laskowski J, Renner B, Le Quintrec M, Panzer S, Hannan JP, Ljubanovic D, Ruseva MM, Borza DB, Antonioli AH, Pickering MC, Holers VM, Thurman JM. Distinct roles for the complement regulators factor H and Crry in protection of the kidney from injury. Kidney Int. 2016 07; 90(1):109-22. PMID: 27165610.
      Citations: 13     Fields:    Translation:Animals
    13. Borza DB. Alternative Pathway Dysregulation and the Conundrum of Complement Activation by IgG4 Immune Complexes in Membranous Nephropathy. Front Immunol. 2016; 7:157. PMID: 27199983.
      Citations: 24     Fields:    
    14. Sueki H, Sato Y, Ohtoshi S, Nakada T, Yoshimura A, Tateishi C, Borza DB, Fader W, Ghohestani RF, Hirako Y, Koga H, Ishii N, Tsuchisaka A, Qian H, Li X, Hashimoto T. A case of subepidermal blistering disease with autoantibodies to multiple laminin subunits who developed later autoantibodies to alpha-5 chain of type IV collagen associated with membranous glomerulonephropathy. Acta Derm Venereol. 2015 Sep; 95(7):826-9. PMID: 25633161.
      Citations: 1     Fields:    Translation:Humans
    15. Gomez IG, MacKenna DA, Johnson BG, Kaimal V, Roach AM, Ren S, Nakagawa N, Xin C, Newitt R, Pandya S, Xia TH, Liu X, Borza DB, Grafals M, Shankland SJ, Himmelfarb J, Portilla D, Liu S, Chau BN, Duffield JS. Anti-microRNA-21 oligonucleotides prevent Alport nephropathy progression by stimulating metabolic pathways. J Clin Invest. 2015 Jan; 125(1):141-56. PMID: 25415439.
      Citations: 194     Fields:    Translation:AnimalsCells
    16. Borza DB. IgG4-restricted anti-glomerular basement membrane autoantibodies targeting quaternary epitopes of native a345(IV) collagen. Am J Kidney Dis. 2014 Jul; 64(1):156-7. PMID: 24954454.
      Citations:    Fields:    Translation:Humans
    17. Olaru F, Luo W, Suleiman H, St John PL, Ge L, Mezo AR, Shaw AS, Abrahamson DR, Miner JH, Borza DB. Neonatal Fc receptor promotes immune complex-mediated glomerular disease. J Am Soc Nephrol. 2014 May; 25(5):918-25. PMID: 24357670.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    18. Fidler AL, Vanacore RM, Chetyrkin SV, Pedchenko VK, Bhave G, Yin VP, Stothers CL, Rose KL, McDonald WH, Clark TA, Borza DB, Steele RE, Ivy MT, Hudson JK, Hudson BG. A unique covalent bond in basement membrane is a primordial innovation for tissue evolution. Proc Natl Acad Sci U S A. 2014 Jan 07; 111(1):331-6. PMID: 24344311.
      Citations: 61     Fields:    Translation:AnimalsCells
    19. Wang F, Jiang RT, Tantawy MN, Borza DB, Takahashi K, Gore JC, Harris RC, Takahashi T, Quarles CC. Repeatability and sensitivity of high resolution blood volume mapping in mouse kidney disease. J Magn Reson Imaging. 2014 Apr; 39(4):866-71. PMID: 24006202.
      Citations: 13     Fields:    Translation:Animals
    20. Borza DB, Zhang JJ, Beck LH, Meyer-Schwesinger C, Luo W. Mouse models of membranous nephropathy: the road less travelled by. Am J Clin Exp Immunol. 2013; 2(2):135-45. PMID: 23885331.
      Citations:    
    21. Olaru F, Luo W, Wang XP, Ge L, Hertz JM, Kashtan CE, Sado Y, Segal Y, Hudson BG, Borza DB. Quaternary epitopes of a345(IV) collagen initiate Alport post-transplant anti-GBM nephritis. J Am Soc Nephrol. 2013 May; 24(6):889-95. PMID: 23620401.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    22. Olaru F, Wang XP, Luo W, Ge L, Miner JH, Kleinau S, Geiger XJ, Wasiluk A, Heidet L, Kitching AR, Borza DB. Proteolysis breaks tolerance toward intact a345(IV) collagen, eliciting novel anti-glomerular basement membrane autoantibodies specific for a345NC1 hexamers. J Immunol. 2013 Feb 15; 190(4):1424-32. PMID: 23303673.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    23. Borza DB, Fogo AB. Interstitial mononuclear infiltrates in murine a3(IV)-NC1-induced nephropathy: harbingers of renal failure? Kidney Int. 2012 Nov; 82(9):1033-4; author reply 1034. PMID: 23064190.
      Citations:    Fields:    Translation:HumansAnimalsCells
    24. Ooi JD, Chang J, Hickey MJ, Borza DB, Fugger L, Holdsworth SR, Kitching AR. The immunodominant myeloperoxidase T-cell epitope induces local cell-mediated injury in antimyeloperoxidase glomerulonephritis. Proc Natl Acad Sci U S A. 2012 Sep 25; 109(39):E2615-24. PMID: 22955884.
      Citations: 44     Fields:    Translation:AnimalsCells
    25. Harrison FE, Best JL, Meredith ME, Gamlin CR, Borza DB, May JM, May JM. Increased expression of SVCT2 in a new mouse model raises ascorbic acid in tissues and protects against paraquat-induced oxidative damage in lung. PLoS One. 2012; 7(4):e35623. PMID: 22558179.
      Citations: 11     Fields:    Translation:AnimalsCells
    26. Zhang JJ, Malekpour M, Luo W, Ge L, Olaru F, Wang XP, Bah M, Sado Y, Heidet L, Kleinau S, Fogo AB, Borza DB. Murine membranous nephropathy: immunization with a3(IV) collagen fragment induces subepithelial immune complexes and Fc?R-independent nephrotic syndrome. J Immunol. 2012 Apr 01; 188(7):3268-77. PMID: 22371398.
      Citations: 16     Fields:    Translation:AnimalsCellsPHPublic Health
    27. Becknell B, Zender GA, Houston R, Baker PB, McBride KL, Luo W, Hains DS, Borza DB, Schwaderer AL. Novel X-linked glomerulopathy is associated with a COL4A5 missense mutation in a non-collagenous interruption. Kidney Int. 2011 Jan; 79(1):120-7. PMID: 20881942.
      Citations: 8     Fields:    Translation:HumansCells
    28. Luo W, Wang XP, Kashtan CE, Borza DB. Alport alloantibodies but not Goodpasture autoantibodies induce murine glomerulonephritis: protection by quinary crosslinks locking cryptic a3(IV) collagen autoepitopes in vivo. J Immunol. 2010 Sep 15; 185(6):3520-8. PMID: 20709951.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    29. Pedchenko V, Bondar O, Fogo AB, Vanacore R, Voziyan P, Kitching AR, Wieslander J, Kashtan C, Borza DB, Neilson EG, Wilson CB, Hudson BG. Molecular architecture of the Goodpasture autoantigen in anti-GBM nephritis. N Engl J Med. 2010 Jul 22; 363(4):343-54. PMID: 20660402.
      Citations: 127     Fields:    Translation:HumansCells
    30. Summers SA, Steinmetz OM, Li M, Kausman JY, Semple T, Edgtton KL, Borza DB, Braley H, Holdsworth SR, Kitching AR. Th1 and Th17 cells induce proliferative glomerulonephritis. J Am Soc Nephrol. 2009 Dec; 20(12):2518-24. PMID: 19820122.
      Citations: 75     Fields:    Translation:AnimalsCells
    31. Abrahamson DR, Hudson BG, Stroganova L, Borza DB, St John PL. Cellular origins of type IV collagen networks in developing glomeruli. J Am Soc Nephrol. 2009 Jul; 20(7):1471-9. PMID: 19423686.
      Citations: 107     Fields:    Translation:AnimalsCells
    32. Gross O, Borza DB, Anders HJ, Licht C, Weber M, Segerer S, Torra R, Gubler MC, Heidet L, Harvey S, Cosgrove D, Lees G, Kashtan C, Gregory M, Savige J, Ding J, Thorner P, Abrahamson DR, Antignac C, Tryggvason K, Hudson B, Miner JH. Stem cell therapy for Alport syndrome: the hope beyond the hype. Nephrol Dial Transplant. 2009 Mar; 24(3):731-4. PMID: 19110486.
      Citations: 16     Fields:    Translation:HumansAnimals
    33. Kang JS, Colon S, Hellmark T, Sado Y, Hudson BG, Borza DB. Identification of noncollagenous sites encoding specific interactions and quaternary assembly of alpha 3 alpha 4 alpha 5(IV) collagen: implications for Alport gene therapy. J Biol Chem. 2008 Dec 12; 283(50):35070-7. PMID: 18930919.
      Citations: 9     Fields:    Translation:HumansCells
    34. Ho J, Gibson IW, Zacharias J, Fervenza F, Colon S, Borza DB. Antigenic heterogeneity of IgA anti-GBM disease: new renal targets of IgA autoantibodies. Am J Kidney Dis. 2008 Oct; 52(4):761-5. PMID: 18752876.
      Citations: 15     Fields:    Translation:Humans
    35. Shimizu H, Aufschnaiter R, Li L, Sarras MP, Borza DB, Abrahamson DR, Sado Y, Zhang X. The extracellular matrix of hydra is a porous sheet and contains type IV collagen. Zoology (Jena). 2008; 111(5):410-418. PMID: 18602803.
      Citations: 18     Fields:    Translation:AnimalsCells
    36. Vanacore RM, Ham AJ, Cartailler JP, Sundaramoorthy M, Todd P, Pedchenko V, Sado Y, Borza DB, Hudson BG. A role for collagen IV cross-links in conferring immune privilege to the Goodpasture autoantigen: structural basis for the crypticity of B cell epitopes. J Biol Chem. 2008 Aug 15; 283(33):22737-48. PMID: 18499662.
      Citations: 20     Fields:    Translation:HumansCells
    37. Xu H, Hu F, Sado Y, Ninomiya Y, Borza DB, Ungvari Z, Lagamma EF, Csiszar A, Nedergaard M, Ballabh P. Maturational changes in laminin, fibronectin, collagen IV, and perlecan in germinal matrix, cortex, and white matter and effect of betamethasone. J Neurosci Res. 2008 May 15; 86(7):1482-500. PMID: 18214989.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    38. Pozzi A, Jarad G, Moeckel GW, Coffa S, Zhang X, Gewin L, Eremina V, Hudson BG, Borza DB, Harris RC, Holzman LB, Phillips CL, Fassler R, Quaggin SE, Miner JH, Zent R. Beta1 integrin expression by podocytes is required to maintain glomerular structural integrity. Dev Biol. 2008 Apr 15; 316(2):288-301. PMID: 18328474.
      Citations: 99     Fields:    Translation:AnimalsCells
    39. Borza CM, Borza DB, Pedchenko V, Saleem MA, Mathieson PW, Sado Y, Hudson HM, Pozzi A, Saus J, Abrahamson DR, Zent R, Hudson BG. Human podocytes adhere to the KRGDS motif of the alpha3alpha4alpha5 collagen IV network. J Am Soc Nephrol. 2008 Apr; 19(4):677-84. PMID: 18235087.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    40. Borza DB. Autoepitopes and alloepitopes of type IV collagen: role in the molecular pathogenesis of anti-GBM antibody glomerulonephritis. Nephron Exp Nephrol. 2007; 106(2):e37-43. PMID: 17570938.
      Citations: 14     Fields:    Translation:HumansCells
    41. Fox MA, Sanes JR, Borza DB, Eswarakumar VP, F?ssler R, Hudson BG, John SW, Ninomiya Y, Pedchenko V, Pfaff SL, Rheault MN, Sado Y, Segal Y, Werle MJ, Umemori H. Distinct target-derived signals organize formation, maturation, and maintenance of motor nerve terminals. Cell. 2007 Apr 06; 129(1):179-93. PMID: 17418794.
      Citations: 130     Fields:    Translation:HumansAnimalsCells
    42. Steenhard BM, Freeburg PB, Isom K, Stroganova L, Borza DB, Hudson BG, St John PL, Zelenchuk A, Abrahamson DR. Kidney development and gene expression in the HIF2alpha knockout mouse. Dev Dyn. 2007 Apr; 236(4):1115-25. PMID: 17342756.
      Citations: 7     Fields:    Translation:AnimalsCells
    43. Kang JS, Kashtan CE, Turner AN, Heidet L, Hudson BG, Borza DB. The alloantigenic sites of alpha3alpha4alpha5(IV) collagen: pathogenic X-linked alport alloantibodies target two accessible conformational epitopes in the alpha5NC1 domain. J Biol Chem. 2007 Apr 06; 282(14):10670-7. PMID: 17293596.
      Citations: 16     Fields:    Translation:HumansCells
    44. Cosgrove D, Kalluri R, Miner JH, Segal Y, Borza DB. Choosing a mouse model to study the molecular pathobiology of Alport glomerulonephritis. Kidney Int. 2007 Apr; 71(7):615-8. PMID: 17290292.
      Citations: 27     Fields:    Translation:Animals
    45. Zent R, Yan X, Su Y, Hudson BG, Borza DB, Moeckel GW, Qi Z, Sado Y, Breyer MD, Voziyan P, Pozzi A. Glomerular injury is exacerbated in diabetic integrin alpha1-null mice. Kidney Int. 2006 Aug; 70(3):460-70. PMID: 16775606.
      Citations: 32     Fields:    Translation:AnimalsCells
    46. Kang JS, Wang XP, Miner JH, Morello R, Sado Y, Abrahamson DR, Borza DB. Loss of alpha3/alpha4(IV) collagen from the glomerular basement membrane induces a strain-dependent isoform switch to alpha5alpha6(IV) collagen associated with longer renal survival in Col4a3-/- Alport mice. J Am Soc Nephrol. 2006 Jul; 17(7):1962-9. PMID: 16769745.
      Citations: 38     Fields:    Translation:AnimalsCells
    47. Borza CM, Pozzi A, Borza DB, Pedchenko V, Hellmark T, Hudson BG, Zent R. Integrin alpha3beta1, a novel receptor for alpha3(IV) noncollagenous domain and a trans-dominant Inhibitor for integrin alphavbeta3. J Biol Chem. 2006 Jul 28; 281(30):20932-20939. PMID: 16731529.
      Citations: 35     Fields:    Translation:HumansCells
    48. Wang XP, Fogo AB, Colon S, Giannico G, Abul-Ezz SR, Miner JH, Borza DB. Distinct epitopes for anti-glomerular basement membrane alport alloantibodies and goodpasture autoantibodies within the noncollagenous domain of alpha3(IV) collagen: a janus-faced antigen. J Am Soc Nephrol. 2005 Dec; 16(12):3563-71. PMID: 16236801.
      Citations: 15     Fields:    Translation:Humans
    49. Borza DB, Bondar O, Colon S, Todd P, Sado Y, Neilson EG, Hudson BG. Goodpasture autoantibodies unmask cryptic epitopes by selectively dissociating autoantigen complexes lacking structural reinforcement: novel mechanisms for immune privilege and autoimmune pathogenesis. J Biol Chem. 2005 Jul 22; 280(29):27147-54. PMID: 15917228.
      Citations: 31     Fields:    Translation:HumansCells
    50. Borza DB. Life without histidine-rich glycoprotein: modulation of the hemostatic balance revisited. J Thromb Haemost. 2005 May; 3(5):863-4. PMID: 15869578.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    51. Borza DB, Chedid MF, Colon S, Lager DJ, Leung N, Fervenza FC. Recurrent Goodpasture's disease secondary to a monoclonal IgA1-kappa antibody autoreactive with the alpha1/alpha2 chains of type IV collagen. Am J Kidney Dis. 2005 Feb; 45(2):397-406. PMID: 15685519.
      Citations: 30     Fields:    Translation:HumansCells
    52. Borza DB, Shipulina NV, Morgan WT. Effects of histidine-proline-rich glycoprotein on plasminogen activation in solution and on surfaces. Blood Coagul Fibrinolysis. 2004 Oct; 15(8):663-72. PMID: 15613921.
      Citations: 1     Fields:    Translation:HumansCells
    53. Borza DB, Neilson EG, Hudson BG. Pathogenesis of Goodpasture syndrome: a molecular perspective. Semin Nephrol. 2003 Nov; 23(6):522-31. PMID: 14631560.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    54. Heidet L, Borza DB, Jouin M, Sich M, Mattei MG, Sado Y, Hudson BG, Hastie N, Antignac C, Gubler MC. A human-mouse chimera of the alpha3alpha4alpha5(IV) collagen protomer rescues the renal phenotype in Col4a3-/- Alport mice. Am J Pathol. 2003 Oct; 163(4):1633-44. PMID: 14507670.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    55. Borza DB, Hudson BG. Molecular characterization of the target antigens of anti-glomerular basement membrane antibody disease. Springer Semin Immunopathol. 2003 May; 24(4):345-61. PMID: 12778332.
      Citations: 12     Fields:    Translation:HumansAnimals
    56. Borza DB, Bondar O, Todd P, Sundaramoorthy M, Sado Y, Ninomiya Y, Hudson BG. Quaternary organization of the goodpasture autoantigen, the alpha 3(IV) collagen chain. Sequestration of two cryptic autoepitopes by intrapromoter interactions with the alpha4 and alpha5 NC1 domains. J Biol Chem. 2002 Oct 18; 277(42):40075-83. PMID: 12193605.
      Citations: 29     Fields:    Translation:HumansCells
    57. Borza DB, Hudson BG. Of mice and men: murine models of anti-GBM antibody nephritis. Kidney Int. 2002 May; 61(5):1905-6. PMID: 11967044.
      Citations: 2     Fields:    Translation:HumansAnimals
    58. Borza DB, Bondar O, Ninomiya Y, Sado Y, Naito I, Todd P, Hudson BG. The NC1 domain of collagen IV encodes a novel network composed of the alpha 1, alpha 2, alpha 5, and alpha 6 chains in smooth muscle basement membranes. J Biol Chem. 2001 Jul 27; 276(30):28532-40. PMID: 11375996.
      Citations: 48     Fields:    Translation:HumansAnimalsCells
    59. David M, Borza DB, Leinonen A, Belmont JM, Hudson BG. Hydrophobic amino acid residues are critical for the immunodominant epitope of the Goodpasture autoantigen. A molecular basis for the cryptic nature of the epitope. J Biol Chem. 2001 Mar 02; 276(9):6370-7. PMID: 11098057.
      Citations: 17     Fields:    Translation:HumansCells
    60. Boutaud A, Borza DB, Bondar O, Gunwar S, Netzer KO, Singh N, Ninomiya Y, Sado Y, Noelken ME, Hudson BG. Type IV collagen of the glomerular basement membrane. Evidence that the chain specificity of network assembly is encoded by the noncollagenous NC1 domains. J Biol Chem. 2000 Sep 29; 275(39):30716-24. PMID: 10896941.
      Citations: 74     Fields:    Translation:HumansAnimalsCells
    61. Borza DB, Netzer KO, Leinonen A, Todd P, Cervera J, Saus J, Hudson BG. The goodpasture autoantigen. Identification of multiple cryptic epitopes on the NC1 domain of the alpha3(IV) collagen chain. J Biol Chem. 2000 Feb 25; 275(8):6030-7. PMID: 10681598.
      Citations: 32     Fields:    Translation:HumansCells
    62. Netzer KO, Leinonen A, Boutaud A, Borza DB, Todd P, Gunwar S, Langeveld JP, Hudson BG. The goodpasture autoantigen. Mapping the major conformational epitope(s) of alpha3(IV) collagen to residues 17-31 and 127-141 of the NC1 domain. J Biol Chem. 1999 Apr 16; 274(16):11267-74. PMID: 10196215.
      Citations: 55     Fields:    Translation:HumansCells
    63. Borza DB, Morgan WT. Histidine-proline-rich glycoprotein as a plasma pH sensor. Modulation of its interaction with glycosaminoglycans by ph and metals. J Biol Chem. 1998 Mar 06; 273(10):5493-9. PMID: 9488672.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    64. Borza DB, Morgan WT. Acceleration of plasminogen activation by tissue plasminogen activator on surface-bound histidine-proline-rich glycoprotein. J Biol Chem. 1997 Feb 28; 272(9):5718-26. PMID: 9102401.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    65. Borza DB, Tatum FM, Morgan WT. Domain structure and conformation of histidine-proline-rich glycoprotein. Biochemistry. 1996 Feb 13; 35(6):1925-34. PMID: 8639676.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
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