Autoimmune diseases affecting multiple endocrine organs. Type I is characterized by childhood onset and chronic mucocutaneous candidiasis (CANDIDIASIS, CHRONIC MUCOCUTANEOUS), while type II exhibits any combination of adrenal insufficiency (ADDISON'S DISEASE), lymphocytic thyroiditis (THYROIDITIS, AUTOIMMUNE;), HYPOPARATHYROIDISM; and gonadal failure. In both types organ-specific ANTIBODIES against a variety of ENDOCRINE GLANDS have been detected. The type II syndrome differs from type I in that it is associated with HLA-A1 and B8 haplotypes, onset is usually in adulthood, and candidiasis is not present.

Descriptor ID	D016884
MeSH Number(s)	C19.787 C20.111.750
Concept/Terms	Polyendocrinopathies, Autoimmune Polyendocrinopathies, Autoimmune Autoimmune Polyendocrinopathy Polyendocrinopathy, Autoimmune Polyglandular Type III Autoimmune Syndrome Polyglandular Type III Autoimmune Syndrome Polyglandular Autoimmune Syndrome, Type 3 Autoimmune Syndrome Type III, Polyglandular Autoimmune Polyglandular Syndrome Type III Autoimmune Polyglandular Syndrome, Type 3 Polyglandular Type I Autoimmune Syndrome Polyglandular Type I Autoimmune Syndrome APECED APS Type 1 Autoimmune Polyendocrinopathy Syndrome Type 1 Autoimmune Polyendocrinopathy with Candidiasis and Ectodermal Dystrophy Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy, Autoimmune Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal-Dystrophy Autoimmune Polyglandular Syndrome Type I Autoimmune Polyglandular Syndrome, Type 1 Autoimmune Polyglandular Syndrome, Type I Autoimmune Syndrome Type I, Polyglandular Polyendocrinopathy-Candidiasis-Ectodermal-Dystrophy, Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy, Autoimmune Polyglandular Autoimmune Syndrome, Type 1 Polyglandular Autoimmune Syndrome, Type I AIRE Deficiency AIRE Deficiencies Deficiency, AIRE Polyglandular Type II Autoimmune Syndrome Polyglandular Type II Autoimmune Syndrome Autoimmune Polyendocrine Syndrome, Type II Autoimmune Polyglandular Syndrome Type II Autoimmune Syndrome Type II, Polyglandular Diabetes Mellitus, Addison Disease, Myxedema Schmidt's Syndrome Syndrome, Schmidt's Multiple Endocrine Deficiency Syndrome, Type 2 Polyendocrine Autoimmune Syndrome, Type II Polyglandular Autoimmune Syndrome, Type 2 Polyglandular Deficiency Syndrome, Type 2 Schmidt Syndrome Syndrome, Schmidt Autoimmune Polyendocrine Syndrome, Type 2 Diabetes Mellitus, Addison's Disease, Myxedema

Below are MeSH descriptors whose meaning is more general than "Polyendocrinopathies, Autoimmune".

Below are MeSH descriptors whose meaning is related to "Polyendocrinopathies, Autoimmune".

Below are MeSH descriptors whose meaning is more specific than "Polyendocrinopathies, Autoimmune".