Diabetes Mellitus, Type 1

"Diabetes Mellitus, Type 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.

Descriptor ID	D003922
MeSH Number(s)	C18.452.394.750.124 C19.246.267 C20.111.327
Concept/Terms	Diabetes Mellitus, Type 1 Diabetes Mellitus, Type 1 Diabetes Mellitus, Brittle Brittle Diabetes Mellitus Diabetes Mellitus, Insulin-Dependent Diabetes Mellitus, Insulin Dependent Insulin-Dependent Diabetes Mellitus Diabetes Mellitus, Juvenile-Onset Diabetes Mellitus, Juvenile Onset Juvenile-Onset Diabetes Mellitus Diabetes Mellitus, Ketosis-Prone Diabetes Mellitus, Ketosis Prone Ketosis-Prone Diabetes Mellitus Juvenile-Onset Diabetes Diabetes, Juvenile-Onset Juvenile Onset Diabetes Diabetes Mellitus, Type I Diabetes Mellitus, Sudden-Onset Diabetes Mellitus, Sudden Onset Mellitus, Sudden-Onset Diabetes Sudden-Onset Diabetes Mellitus Type 1 Diabetes Mellitus Diabetes Mellitus, Insulin-Dependent, 1 Insulin-Dependent Diabetes Mellitus 1 Insulin Dependent Diabetes Mellitus 1 Type 1 Diabetes Diabetes, Type 1 IDDM Diabetes, Autoimmune Diabetes, Autoimmune Autoimmune Diabetes

Below are MeSH descriptors whose meaning is more general than "Diabetes Mellitus, Type 1".

Diseases [C]
Nutritional and Metabolic Diseases [C18]
Metabolic Diseases [C18.452]
Glucose Metabolism Disorders [C18.452.394]
Diabetes Mellitus [C18.452.394.750]
Diabetes Mellitus, Type 1 [C18.452.394.750.124]
Endocrine System Diseases [C19]
Diabetes Mellitus [C19.246]
Diabetes Mellitus, Type 1 [C19.246.267]
Immune System Diseases [C20]
Autoimmune Diseases [C20.111]
Diabetes Mellitus, Type 1 [C20.111.327]

Below are MeSH descriptors whose meaning is related to "Diabetes Mellitus, Type 1".

Below are MeSH descriptors whose meaning is more specific than "Diabetes Mellitus, Type 1".

Diabetes Mellitus, Type 1
Wolfram Syndrome

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Diabetes Mellitus, Type 1" by people in this website by year, and whether "Diabetes Mellitus, Type 1" was a major or minor topic of these publications.

Bar chart showing 73 publications over 27 distinct years, with a maximum of 6 publications in 2012 and 2024

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	1	0	1
1998	1	0	1
1999	0	1	1
2000	3	0	3
2001	2	1	3
2002	2	0	2
2003	3	2	5
2004	3	0	3
2005	1	0	1
2007	0	1	1
2008	2	0	2
2009	1	0	1
2010	2	0	2
2011	1	0	1
2012	5	1	6
2014	4	0	4
2015	3	1	4
2016	4	0	4
2017	2	0	2
2018	3	0	3
2019	2	0	2
2020	3	0	3
2021	3	0	3
2022	2	0	2
2023	2	0	2
2024	3	3	6
2025	5	0	5

Below are the most recent publications written about "Diabetes Mellitus, Type 1" by people in Profiles.

Saarah P, Syeda ZA, Xu Z, Dong Y, Jiang H, Shanguhyia M, Roy S, Zhu B, Zhang L, Dewan AT, Asgari S, Alagpulinsa DA. Shared genetic and neuroimmune architecture links type 1 diabetes with neurocognitive traits. Nat Commun. 2026 Mar 13; 17(1).

View in: PubMed
Cruz-Vespa N, Thomas ML, McCarthy MJ, Meruelo AD. Depression Risk in Type 1 Versus Type 2 Diabetes: Cross-Sectional Analysis of Body Mass Index (BMI) in a Nationally Diverse Cohort. Endocrinol Diabetes Metab. 2026 Mar; 9(2):e70172.

View in: PubMed
Landry LG, Wells KL, Anderson AM, Miller KR, Jones KL, Michels AW, Nakayama M. Quantitative V gene-targeted T cell receptor sequencing as a biomarker in type 1 diabetes. JCI Insight. 2026 Feb 09; 11(3).

View in: PubMed
Nnamani DO, Choi S, Ofosu-Boateng M, Gebreyesus LH, Twum E, Polunas M, Goedken M, Yadak N, Dagogo-Jack S, Ahima RS, Yeyeodu ST, Gonzalez FJ, Gyamfi MA. Role of the xenobiotic-activated pregnane?X?receptor in type 1 and type 2 diabetes in male mice. Biochem Pharmacol. 2026 Jan; 243(Pt 1):117482.

View in: PubMed
F?l?p K, Koz?k E, Tok?si N, Kocsis L, Kelemen A, Geszti Z, Kut?s A, Harangi M, Di?szegi ?, Rapi Z, Balla J, Le Saux O, V?radi A, Pomozi V. Diabetes-induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice. FEBS Open Bio. 2026 Mar; 16(3):474-486.

View in: PubMed
Lu CC, Chang CH, Chou JC, Yu PL, Wang PS. Regulatory mechanism of ghrelin on testosterone secretion in type 1 diabetic rats. Reprod Fertil. 2025 07 01; 6(3).

View in: PubMed
Jeddi S, Kashfi K, Ghasemi A. The potential role of nitrate, a nitric oxide donor, in the prevention and treatment of diabetic osteoporosis. Front Endocrinol (Lausanne). 2025; 16:1480838.

View in: PubMed
Sobhani NC, Huang Y, Venkatesh KK, Wright JD, Friedman AM, Wen T. Diabetes Technology Use in Pregnancies with Type 1 Diabetes in the United States from 2009 to 2020. Am J Perinatol. 2026 03; 43(4):453-460.

View in: PubMed
Shao H, Thorpe LE, Islam S, Bian J, Guo Y, Li P, Bost S, Dabelea D, Conway R, Crume T, Schwartz BS, Hirsch AG, Allen KS, Dixon BE, Grannis SJ, Lustigova E, Reynolds K, Rosenman M, Zhong VW, Wong A, Rivera P, Le T, Akerman M, Conderino S, Rajan A, Liese AD, Rudisill C, Obeid JS, Ewing JA, Bailey C, Mendonca EA, Zaganjor I, Rolka D, Imperatore G, Pavkov ME, Divers J. Developing a Computable Phenotype for Identifying Children, Adolescents, and Young Adults With Diabetes Using Electronic Health Records in the DiCAYA Network. Diabetes Care. 2025 Jun 01; 48(6):914-921.

View in: PubMed
Nicholas CA, Tensun FA, Evans SA, Toole KP, Prendergast JE, Broncucia H, Hesselberth JR, Gottlieb PA, Wells KL, Smith MJ. Activated polyreactive B cells are clonally expanded in autoantibody positive and patients with recent-onset type 1 diabetes. Cell Rep. 2025 Apr 22; 44(4):115425.

View in: PubMed

People

Explore

Similar Concepts

Top Journals