"Insulin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).
Descriptor ID |
D007328
|
MeSH Number(s) |
D06.472.699.587.200.500.625 D12.644.548.586.200.500.625
|
Concept/Terms |
Insulin- Insulin
- Insulin, Regular
- Regular Insulin
- Soluble Insulin
- Insulin, Soluble
|
Below are MeSH descriptors whose meaning is more general than "Insulin".
Below are MeSH descriptors whose meaning is more specific than "Insulin".
This graph shows the total number of publications written about "Insulin" by people in this website by year, and whether "Insulin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1999 | 1 | 1 | 2 |
2000 | 1 | 0 | 1 |
2001 | 1 | 1 | 2 |
2002 | 2 | 3 | 5 |
2003 | 2 | 1 | 3 |
2004 | 5 | 1 | 6 |
2005 | 4 | 5 | 9 |
2006 | 2 | 8 | 10 |
2007 | 3 | 5 | 8 |
2008 | 2 | 2 | 4 |
2009 | 6 | 2 | 8 |
2010 | 3 | 6 | 9 |
2011 | 6 | 9 | 15 |
2012 | 6 | 1 | 7 |
2013 | 6 | 5 | 11 |
2014 | 5 | 12 | 17 |
2015 | 6 | 4 | 10 |
2016 | 4 | 6 | 10 |
2017 | 2 | 3 | 5 |
2018 | 0 | 3 | 3 |
2019 | 6 | 3 | 9 |
2020 | 2 | 5 | 7 |
2021 | 2 | 3 | 5 |
2022 | 3 | 5 | 8 |
2023 | 0 | 4 | 4 |
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Below are the most recent publications written about "Insulin" by people in Profiles.
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Moss ND, Wells KL, Theis A, Kim YK, Spigelman AF, Liu X, MacDonald PE, Sussel L. Modulation of insulin secretion by RBFOX2-mediated alternative splicing. Nat Commun. 2023 Nov 25; 14(1):7732.
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Lopez-Candales A, Monte S, Sawalha K, Norgard NB. Time to revisit the true role of metformin in type 2 diabetes mellitus. Postgrad Med. 2023 08; 135(6):539-542.
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Stensland ZC, Magera CA, Broncucia H, Gomez BD, Rios-Guzman NM, Wells KL, Nicholas CA, Rihanek M, Hunter MJ, Toole KP, Gottlieb PA, Smith MJ. Identification of an anergic BND cell-derived activated B cell population (BND2) in young-onset type 1 diabetes patients. J Exp Med. 2023 08 07; 220(8).
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Vass RA, Bell EF, Roghair RD, Kiss G, Funke S, Bokor S, Moln?r D, Miseta A, B?dis J, Kov?cs K, Ertl T. Insulin, Testosterone, and Albumin in Term and Preterm Breast Milk, Donor Milk, and Infant Formula. Nutrients. 2023 Mar 19; 15(6).
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Davidson MB. A simplified straightforward protocol for the use of U-500 regular insulin. Diabetes Obes Metab. 2023 02; 25(2):634-636.
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Wang Z, Tang X, Swaminathan SK, Kandimalla KK, Kalari KR. Mapping the dynamics of insulin-responsive pathways in the blood-brain barrier endothelium using time-series transcriptomics data. NPJ Syst Biol Appl. 2022 08 16; 8(1):29.
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Nakamura NK, Tokunaga DS, Ha HY, Polgar N. The Exocyst Is Required for CD36 Fatty Acid Translocase Trafficking and Free Fatty Acid Uptake in Skeletal Muscle Cells. Cells. 2022 08 06; 11(15).
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Wang L, Wiedmann TS, Kandimalla KK. Modulating insulin signaling and trafficking at the blood-brain barrier endothelium using lipid based nanoemulsions. Int J Pharm. 2022 Jun 25; 622:121823.
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Xu NY, Nguyen KT, DuBord AY, Pickup J, Sherr JL, Teymourian H, Cengiz E, Ginsberg BH, Cobelli C, Ahn D, Bellazzi R, Bequette BW, Gandrud Pickett L, Parks L, Spanakis EK, Masharani U, Akturk HK, Melish JS, Kim S, Kang GE, Klonoff DC. Diabetes Technology Meeting 2021. J Diabetes Sci Technol. 2022 07; 16(4):1016-1056.
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Davidson MB. Comment on Aleppo et al. The Effect of Discontinuing Continuous Monitoring in Adults With Type 2 Diabetes Treated With Basal Insulin. Diabetes Care 2021;44:2729-2737. Diabetes Care. 2022 04 01; 45(4):e84.