Leptin

"Leptin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A 16-kDa peptide hormone secreted from WHITE ADIPOCYTES. Leptin serves as a feedback signal from fat cells to the CENTRAL NERVOUS SYSTEM in regulation of food intake, energy balance, and fat storage.

Descriptor ID	D020738
MeSH Number(s)	D06.472.699.042.500 D12.644.276.024.500 D12.644.548.011.500 D12.776.467.024.500 D23.529.024.500
Concept/Terms	Leptin Leptin Obese Protein Obese Gene Product Gene Product, Obese Ob Gene Product Gene Product, Ob Ob Protein

Below are MeSH descriptors whose meaning is more general than "Leptin".

Chemicals and Drugs [D]
Hormones, Hormone Substitutes, and Hormone Antagonists [D06]
Hormones [D06.472]
Peptide Hormones [D06.472.699]
Adipokines [D06.472.699.042]
Leptin [D06.472.699.042.500]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intercellular Signaling Peptides and Proteins [D12.644.276]
Adipokines [D12.644.276.024]
Leptin [D12.644.276.024.500]
Peptide Hormones [D12.644.548]
Adipokines [D12.644.548.011]
Leptin [D12.644.548.011.500]
Proteins [D12.776]
Intercellular Signaling Peptides and Proteins [D12.776.467]
Adipokines [D12.776.467.024]
Leptin [D12.776.467.024.500]
Biological Factors [D23]
Intercellular Signaling Peptides and Proteins [D23.529]
Adipokines [D23.529.024]
Leptin [D23.529.024.500]

Below are MeSH descriptors whose meaning is related to "Leptin".

Below are MeSH descriptors whose meaning is more specific than "Leptin".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Leptin" by people in this website by year, and whether "Leptin" was a major or minor topic of these publications.

Bar chart showing 77 publications over 20 distinct years, with a maximum of 9 publications in 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	0	1	1
2003	1	2	3
2004	2	1	3
2005	1	0	1
2006	4	1	5
2007	5	0	5
2008	2	1	3
2009	4	0	4
2010	3	3	6
2011	5	2	7
2012	3	2	5
2013	5	4	9
2014	1	2	3
2015	2	1	3
2017	2	0	2
2018	1	3	4
2019	4	0	4
2020	1	1	2
2021	3	0	3
2022	2	2	4

Below are the most recent publications written about "Leptin" by people in Profiles.

Cruz B, Casta?eda K, Aranda M, Hinojosa CA, Castro-Gutierrez R, Flores RJ, Spencer CT, Vozella V, Roberto M, Gadad BS, Roychowdhury S, O'Dell LE. Alcohol self-administration and nicotine withdrawal alter biomarkers of stress and inflammation and prefrontal cortex changes in G? subunits. Am J Drug Alcohol Abuse. 2023 05 04; 49(3):321-332.

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Islam T, Ahsan MA, Hassan M, Afrin H, Pena-Zacarias J, Aldalbahi A, Alvarado-Tenorio B, Noveron JC, Nurunnabi M. Detection of Leptin Using Electrocatalyst Mediated Impedimetric Sensing. ACS Biomater Sci Eng. 2023 05 08; 9(5):2170-2180.

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Rios-Colon L, Chijioke J, Niture S, Afzal Z, Qi Q, Srivastava A, Ramalinga M, Kedir H, Cagle P, Arthur E, Sharma M, Moore J, Deep G, Suy S, Collins SP, Kumar D. Leptin modulated microRNA-628-5p targets Jagged-1 and inhibits prostate cancer hallmarks. Sci Rep. 2022 06 16; 12(1):10073.

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Cairat M, Rinaldi S, Navionis AS, Romieu I, Biessy C, Viallon V, Olsen A, Tj?nneland A, Fournier A, Severi G, Kvaskoff M, Fortner RT, Kaaks R, Aleksandrova K, Schulze MB, Masala G, Tumino R, Sieri S, Grasso C, Mattiello A, Gram IT, Olsen KS, Agudo A, Etxezarreta PA, S?nchez MJ, Santiuste C, Barricarte A, Monninkhof E, Hiensch AE, Muller D, Merritt MA, Travis RC, Weiderpass E, Gunter MJ, Dossus L. Circulating inflammatory biomarkers, adipokines and breast cancer risk-a case-control study nested within the EPIC cohort. BMC Med. 2022 04 18; 20(1):118.

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Torres DJ, Pitts MW, Seale LA, Hashimoto AC, An KJ, Hanato AN, Hui KW, Remigio SMA, Carlson BA, Hatfield DL, Berry MJ. Female Mice with Selenocysteine tRNA Deletion in Agrp Neurons Maintain Leptin Sensitivity and Resist Weight Gain While on a High-Fat Diet. Int J Mol Sci. 2021 Oct 12; 22(20).

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Torres DJ, Pitts MW. Pericytic porters: helping leptin step in. Trends Endocrinol Metab. 2021 12; 32(12):958-959.

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Beales ILP, Ogunwobi OO. Leptin activates Akt in oesophageal cancer cells via multiple atorvastatin-sensitive small GTPases. Mol Cell Biochem. 2021 Jun; 476(6):2307-2316.

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Tchio C, Baba K, Piccione G, Tosini G. Removal of melatonin receptor type 1 signalling induces dyslipidaemia and hormonal changes in mice subjected to environmental circadian disruption. Endocrinol Diabetes Metab. 2021 01; 4(1):e00171.

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Lipsey CC, Harbuzariu A, Robey RW, Huff LM, Gottesman MM, Gonzalez-Perez RR. Leptin Signaling Affects Survival and Chemoresistance of Estrogen Receptor Negative Breast Cancer. Int J Mol Sci. 2020 May 27; 21(11).

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Bidulescu A, Dinh PC, Sarwary S, Forsyth E, Luetke MC, King DB, Liu J, Davis SK, Correa A. Associations of leptin and adiponectin with incident type 2 diabetes and interactions among African Americans: the Jackson heart study. BMC Endocr Disord. 2020 Mar 04; 20(1):31.

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