Epitopes

"Epitopes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Sites on an antigen that interact with specific antibodies.

Descriptor ID	D000939
MeSH Number(s)	D23.050.550
Concept/Terms	Epitopes Epitopes Antigenic Determinants Determinants, Antigenic Antigenic Specificity Antigenic Specificity Specificity, Antigenic

Below are MeSH descriptors whose meaning is more general than "Epitopes".

Chemicals and Drugs [D]
Biological Factors [D23]
Antigens [D23.050]
Epitopes [D23.050.550]

Below are MeSH descriptors whose meaning is related to "Epitopes".

Below are MeSH descriptors whose meaning is more specific than "Epitopes".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Epitopes" by people in this website by year, and whether "Epitopes" was a major or minor topic of these publications.

Bar chart showing 90 publications over 27 distinct years, with a maximum of 8 publications in 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	1	1	2
1999	1	0	1
2000	2	0	2
2001	1	0	1
2002	0	3	3
2003	0	3	3
2004	0	6	6
2005	1	5	6
2006	0	1	1
2007	1	1	2
2008	1	3	4
2009	1	1	2
2010	3	3	6
2011	2	4	6
2012	3	2	5
2013	1	7	8
2014	0	2	2
2015	2	3	5
2016	1	4	5
2017	0	1	1
2018	1	3	4
2019	0	1	1
2021	1	2	3
2022	0	4	4
2023	0	1	1
2024	1	3	4
2025	2	0	2

Below are the most recent publications written about "Epitopes" by people in Profiles.

Thangaiyan R, Shanker A, Ballard BR, M'Koma AE. Structural and epitope characterization of anti-DEFA5 monoclonal antibodies clones 1A8 and 4F5 for inflammatory bowel disease subtype diagnostics. Int J Biol Macromol. 2025 Nov; 330(Pt 3):148024.

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Xiong Z, Sneiderman CT, Kuminkoski CR, Reinheimer J, Schwegman L, Sever RE, Habib A, Hu B, Agnihotri S, Rajasundaram D, Zinn PO, Forsthuber TG, Pollack IF, Li X, Raphael I, Kohanbash G. Transcript-targeted antigen mapping reveals the potential of POSTN splicing junction epitopes in glioblastoma immunotherapy. Genes Immun. 2025 Jun; 26(3):190-199.

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Alves CC, Lewis J, Antunes DA, Donadi EA. The Role of Vimentin Peptide Citrullination in the Structure and Dynamics of HLA-DRB1 Rheumatoid Arthritis Risk-Associated Alleles. Int J Mol Sci. 2024 Dec 24; 26(1).

View in: PubMed
Soeda Y, Hayashi E, Nakatani N, Ishigaki S, Takaichi Y, Tachibana T, Riku Y, Chambers JK, Koike R, Mohammad M, Takashima A. A novel monoclonal antibody generated by immunization with granular tau oligomers binds to tau aggregates at 423-430 amino acid sequence. Sci Rep. 2024 07 26; 14(1):16391.

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Hurtado J, Rogers TF, Jaffe DB, Adams BA, Bangaru S, Garcia E, Capozzola T, Messmer T, Sharma P, Song G, Beutler N, He W, Dueker K, Musharrafieh R, Burbach S, Truong A, Stubbington MJT, Burton DR, Andrabi R, Ward AB, McDonnell WJ, Briney B. Deep repertoire mining uncovers ultra-broad coronavirus neutralizing antibodies targeting multiple spike epitopes. Cell Rep. 2024 06 25; 43(6):114307.

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Tanner T, Medhavi FNU, Richardson S, Omosun YO, Eko FO. In silico design and analysis of a multiepitope vaccine against Chlamydia. Pathog Dis. 2024 02 07; 82.

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Mondal T, Gaur H, Wamba BEN, Michalak AG, Stout C, Watson MR, Aleixo SL, Singh A, Condello S, Faller R, Leiserowitz GS, Bhatnagar S, Tushir-Singh J. Characterizing the regulatory Fas (CD95) epitope critical for agonist antibody targeting and CAR-T bystander function in ovarian cancer. Cell Death Differ. 2023 11; 30(11):2408-2431.

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Maison DP, Ching LL, Cleveland SB, Tseng AC, Nakano E, Shikuma CM, Nerurkar VR. Dynamic SARS-CoV-2 emergence algorithm for rationally-designed logical next-generation vaccines. Commun Biol. 2022 10 10; 5(1):1081.

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Orlando BJ, Dominik PK, Roy S, Ogbu CP, Erramilli SK, Kossiakoff AA, Vecchio AJ. Development, structure, and mechanism of synthetic antibodies that target claudin and Clostridium perfringens enterotoxin complexes. J Biol Chem. 2022 09; 298(9):102357.

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Conev A, Devaurs D, Rigo MM, Antunes DA, Kavraki LE. 3pHLA-score improves structure-based peptide-HLA binding affinity prediction. Sci Rep. 2022 06 24; 12(1):10749.

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