Vaccines, Synthetic

"Vaccines, Synthetic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Small synthetic peptides that mimic surface antigens of pathogens and are immunogenic, or vaccines manufactured with the aid of recombinant DNA techniques. The latter vaccines may also be whole viruses whose nucleic acids have been modified.

Descriptor ID	D014614
MeSH Number(s)	D12.776.828.868 D20.215.894.865 D23.050.865
Concept/Terms	Vaccines, Synthetic Vaccines, Synthetic Synthetic Vaccines Synthetic Immunogens Immunogens, Synthetic Semisynthetic Vaccines Semisynthetic Vaccines Vaccines, Semisynthetic Antigens, Synthetic Antigens, Synthetic Synthetic Antigens Molecular Vaccines Molecular Vaccines Vaccines, Molecular Vaccines, Chemical Chemical Vaccines Vaccines, Recombinant Vaccines, Recombinant Recombinant Vaccines

Below are MeSH descriptors whose meaning is more general than "Vaccines, Synthetic".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Recombinant Proteins [D12.776.828]
Vaccines, Synthetic [D12.776.828.868]
Complex Mixtures [D20]
Biological Products [D20.215]
Vaccines [D20.215.894]
Vaccines, Synthetic [D20.215.894.865]
Biological Factors [D23]
Antigens [D23.050]
Vaccines, Synthetic [D23.050.865]

Below are MeSH descriptors whose meaning is more specific than "Vaccines, Synthetic".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Vaccines, Synthetic" by people in this website by year, and whether "Vaccines, Synthetic" was a major or minor topic of these publications.

Bar chart showing 60 publications over 23 distinct years, with a maximum of 7 publications in 2006

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	0	1	1
2001	1	0	1
2002	0	1	1
2003	2	1	3
2004	2	0	2
2005	0	1	1
2006	1	6	7
2007	0	2	2
2008	0	2	2
2009	1	5	6
2010	1	5	6
2012	0	5	5
2013	1	1	2
2014	0	1	1
2015	0	3	3
2017	0	3	3
2018	1	1	2
2019	1	0	1
2020	0	1	1
2021	0	2	2
2022	0	3	3
2025	0	3	3
2026	0	2	2

Below are the most recent publications written about "Vaccines, Synthetic" by people in Profiles.

Fong Y, Huang Y, Huang Y, Woo W, McGarry A, ??ez G, Dunkle LM, Cho I, Houchens CR, Martins K, Jayashankar L, Castellino F, Petropoulos CJ, Leith A, Haugaard D, Webb W, Lu Y, Yu C, Carpp LN, Randhawa AK, Andrasik MP, Kublin JG, Hutter J, Keshtkar-Jahromi M, Beresnev TH, Rodriguez CA, Tapia M, Turley CB, Zorrilla CD, Cohen SH, Kline SE, Barranco E, Corey L, Neuzil KM, Follmann D, Ake JA, Gay CL, Kotloff KL, Jones T, Koup RA, Donis RO, Gilbert PB. Analysis of Antibody Markers as Immune Correlates of Risk of Severe COVID-19 in the PREVENT-19 Efficacy Trial of the NVX-CoV2373 Recombinant Protein Vaccine. Clin Infect Dis. 2026 Apr 30; 82(4):e863-e874.

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Stromberg ZR, Silva EE, Johnston SC, Johnson DM, Hall D, Adjei EF, Altin JA, Abisoye-Ogunniyan A, Gollott T, He W, Jones IKA, Kwilas S, Lund SJ, Mead HL, Nelson GA, Ouyang L, Peters SKG, Schwedler JL, Trecazzi CZ, Turner MW, Ye C, Bradfute SB, Fischer NO, Hooper JW, Ladner JT, Rasley A, Negrete OA. An mRNA vaccine encoding the Ebola virus glycoprotein induces high neutralizing antibody titers and provides strong protection against lethal infections in mouse models. Front Immunol. 2025; 16:1682418.

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Mayerlen LI, Wong TAS, To A, Smith O, Chuang E, Donini O, Lehrer AT. Thermostable bivalent & trivalent filovirus vaccines from insect cells: potency demonstrated after 3?months and 2?years. Vaccine. 2025 Oct 03; 64:127684.

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Fong Y, Dang L, Zhang B, Fintzi J, Chen S, Wang J, Rouphael NG, Branche AR, Diemert DJ, Falsey AR, Losada C, Baden LR, Frey SE, Whitaker JA, Little SJ, Kamidani S, Walter EB, Novak RM, Rupp R, Jackson LA, Yu C, Magaret CA, Molitor C, Borate B, Babu TM, Kottkamp AC, Luetkemeyer AF, Immergluck LC, Presti RM, B?cker M, Winokur PL, Mahgoub SM, Goepfert PA, Fusco DN, Atmar RL, Posavad CM, Mu J, Makowski M, Makhene MK, Nayak SU, Roberts PC, Follmann D, Gilbert PB. Neutralizing Antibody Immune Correlates for a Recombinant Protein Vaccine in the COVAIL Trial. Clin Infect Dis. 2025 02 05; 80(1):223-227.

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Zhang B, Fong Y, Dang L, Fintzi J, Chen S, Wang J, Rouphael NG, Branche AR, Diemert DJ, Falsey AR, Graciaa DS, Baden LR, Frey SE, Whitaker JA, Little SJ, Kamidani S, Walter EB, Novak RM, Rupp R, Jackson LA, Yu C, Magaret CA, Molitor C, Borate B, Busch S, Benkeser D, Netzl A, Smith DJ, Babu TM, Kottkamp AC, Luetkemeyer AF, Immergluck LC, Presti RM, B?cker M, Winokur PL, Mahgoub SM, Goepfert PA, Fusco DN, Atmar RL, Posavad CM, Mu J, Makowski M, Makhene MK, Nayak SU, Roberts PC, Gilbert PB, Follmann D. Neutralizing antibody immune correlates in COVAIL trial recipients of an mRNA second COVID-19 vaccine boost. Nat Commun. 2025 Jan 17; 16(1):759.

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Williams CA, Wong TAS, Ball AH, Lieberman MM, Lehrer AT. Maternal Immunization Using a Protein Subunit Vaccine Mediates Passive Immunity against Zaire ebolavirus in a Murine Model. Viruses. 2022 12 14; 14(12).

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Kwon JH, Tenforde MW, Gaglani M, Talbot HK, Ginde AA, McNeal T, Ghamande S, Douin DJ, Casey JD, Mohr NM, Zepeski A, Shapiro NI, Gibbs KW, Files DC, Hager DN, Shehu A, Prekker ME, Caspers SD, Exline MC, Botros M, Gong MN, Li A, Mohamed A, Johnson NJ, Srinivasan V, Steingrub JS, Peltan ID, Brown SM, Martin ET, Khan A, Hough CL, Busse LW, Duggal A, Wilson JG, Perez C, Chang SY, Mallow C, Rovinski R, Babcock HM, Lauring AS, Felley L, Halasa N, Chappell JD, Grijalva CG, Rice TW, Womack KN, Lindsell CJ, Hart KW, Baughman A, Olson SM, Schrag S, Kobayashi M, Verani JR, Patel MM, Self WH. mRNA Vaccine Effectiveness Against Coronavirus Disease 2019 Hospitalization Among Solid Organ Transplant Recipients. J Infect Dis. 2022 09 13; 226(5):797-807.

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Mazuecos A, Villanego F, Zarraga S, L?pez V, Oppenheimer F, Llin?s-Mallol L, Hern?ndez AM, Rivas A, Ruiz-Fuentes MC, Toapanta NG, Jim?nez C, Cabello S, Beneyto I, Aladr?n MJ, Rodr?guez-Benot A, Canal C, Molina M, P?rez-Flores I, Saura IM, Gavela E, Franco A, Lorenzo I, Galeano C, Tabernero G, P?rez-Tamaj?n L, Mart?n-Moreno PL, Fern?ndez-Gir?n F, Siverio O, Labrador PJ, De Arriba G, Simal F, Cruzado L, Moina I, Alcalde G, S?nchez-?lvarez E, Pascual J, Crespo M. Breakthrough Infections Following mRNA SARS-CoV-2 Vaccination in Kidney Transplant Recipients. Transplantation. 2022 07 01; 106(7):1430-1439.

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Lehrer AT, Chuang E, Namekar M, Williams CA, Wong TAS, Lieberman MM, Granados A, Misamore J, Yalley-Ogunro J, Andersen H, Geisbert JB, Agans KN, Cross RW, Geisbert TW. Recombinant Protein Filovirus Vaccines Protect Cynomolgus Macaques From Ebola, Sudan, and Marburg Viruses. Front Immunol. 2021; 12:703986.

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Ricci G, Minsker K, Kapish A, Osborn J, Ha S, Davide J, Califano JP, Sehlin D, Rustandi RR, Dick LW, Vlasak J, Culp TD, Baudy A, Bell E, Mukherjee M. Flow virometry for process monitoring of live virus vaccines-lessons learned from ERVEBO. Sci Rep. 2021 04 01; 11(1):7432.

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