Recombinant DNA vectors encoding antigens administered for the prevention or treatment of disease. The host cells take up the DNA, express the antigen, and present it to the immune system in a manner similar to that which would occur during natural infection. This induces humoral and cellular immune responses against the encoded antigens. The vector is called naked DNA because there is no need for complex formulations or delivery agents; the plasmid is injected in saline or other buffers.

Descriptor ID	D019444
MeSH Number(s)	D12.776.828.868.910 D20.215.894.865.910 D23.050.865.910
Concept/Terms	Vaccines, DNA Vaccines, DNA Recombinant DNA Vaccines DNA Vaccines, Recombinant DNA Vaccines Naked DNA Vaccines DNA Vaccines, Naked Vaccines, Naked DNA Vaccines, Recombinant DNA Polynucleotide Vaccines Polynucleotide Vaccines Vaccines, Polynucleotide Nucleic Acid Vaccines Nucleic Acid Vaccines Vaccines, Nucleic Acid

Below are MeSH descriptors whose meaning is more general than "Vaccines, DNA".

Below are MeSH descriptors whose meaning is related to "Vaccines, DNA".

Below are MeSH descriptors whose meaning is more specific than "Vaccines, DNA".