Immunodominant Epitopes

"Immunodominant Epitopes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Subunits of the antigenic determinant that are most easily recognized by the immune system and thus most influence the specificity of the induced antibody.

Descriptor ID	D016056
MeSH Number(s)	D23.050.550.500
Concept/Terms	Immunodominant Epitopes Immunodominant Epitopes Immunodominant Determinants Determinants, Immunodominant Immunodominant Domains Domains, Immunodominant Immunodominant Sites Sites, Immunodominant Immunodominant Regions Regions, Immunodominant Antigenic Determinants, Immunodominant Determinants, Immunodominant Antigenic Immunodominant Antigenic Determinants Epitopes, Immunodominant Antigens, Immunodominant Antigens, Immunodominant Immunodominant Antigens

Below are MeSH descriptors whose meaning is more general than "Immunodominant Epitopes".

Chemicals and Drugs [D]
Biological Factors [D23]
Antigens [D23.050]
Epitopes [D23.050.550]
Immunodominant Epitopes [D23.050.550.500]

Below are MeSH descriptors whose meaning is related to "Immunodominant Epitopes".

Below are MeSH descriptors whose meaning is more specific than "Immunodominant Epitopes".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Immunodominant Epitopes" by people in this website by year, and whether "Immunodominant Epitopes" was a major or minor topic of these publications.

Bar chart showing 21 publications over 17 distinct years, with a maximum of 2 publications in 2006 and 2011 and 2012 and 2014

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	1	0	1
1997	0	1	1
1998	0	1	1
1999	0	1	1
2000	1	0	1
2001	0	1	1
2002	1	0	1
2004	1	0	1
2006	0	2	2
2007	0	1	1
2009	1	0	1
2010	1	0	1
2011	0	2	2
2012	2	0	2
2013	0	1	1
2014	2	0	2
2015	0	1	1

Below are the most recent publications written about "Immunodominant Epitopes" by people in Profiles.

Ram?rez M, Santos S, Mart?nez O, Rodr?guez R, Miranda E, Ramos-Perez WD, Otero M. Characterization of the immune response elicited by the vaccinia virus L3 protein delivered as naked DNA. Vaccine. 2018 04 05; 36(15):2049-2055.

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Hoffmann PR, Panigada M, Soprana E, Terry F, Bandar IS, Napolitano A, Rose AH, Hoffmann FW, Ndhlovu LC, Belcaid M, Moise L, De Groot AS, Carbone M, Gaudino G, Matsui T, Siccardi A, Bertino P. Preclinical development of HIvax: Human survivin highly immunogenic vaccines. Hum Vaccin Immunother. 2015; 11(7):1585-95.

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Chu P, Cunningham AL, Yu JJ, Nguyen JQ, Barker JR, Lyons CR, Wilder J, Valderas M, Sherwood RL, Arulanandam BP, Klose KE. Live attenuated Francisella novicida vaccine protects against Francisella tularensis pulmonary challenge in rats and non-human primates. PLoS Pathog. 2014 Oct; 10(10):e1004439.

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Singh R, Gupta P, Sharma PK, Ades EW, Hollingshead SK, Singh S, Lillard JW. Prediction and characterization of helper T-cell epitopes from pneumococcal surface adhesin A. Immunology. 2014 Apr; 141(4):514-30.

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Gilchuk P, Spencer CT, Conant SB, Hill T, Gray JJ, Niu X, Zheng M, Erickson JJ, Boyd KL, McAfee KJ, Oseroff C, Hadrup SR, Bennink JR, Hildebrand W, Edwards KM, Crowe JE, Williams JV, Buus S, Sette A, Schumacher TN, Link AJ, Joyce S. Discovering naturally processed antigenic determinants that confer protective T cell immunity. J Clin Invest. 2013 May; 123(5):1976-87.

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Arellano B, Hussain R, Zacharias T, Yoon J, David C, Zein S, Steinman L, Forsthuber T, Greenberg BM, Lambracht-Washington D, Ritchie AM, Bennett JL, St?ve O. Human aquaporin 4281-300 is the immunodominant linear determinant in the context of HLA-DRB1*03:01: relevance for diagnosing and monitoring patients with neuromyelitis optica. Arch Neurol. 2012 Sep; 69(9):1125-31.

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Dreyfus C, Laursen NS, Kwaks T, Zuijdgeest D, Khayat R, Ekiert DC, Lee JH, Metlagel Z, Bujny MV, Jongeneelen M, van der Vlugt R, Lamrani M, Korse HJ, Geelen E, Sahin ?, Sieuwerts M, Brakenhoff JP, Vogels R, Li OT, Poon LL, Peiris M, Koudstaal W, Ward AB, Wilson IA, Goudsmit J, Friesen RH. Highly conserved protective epitopes on influenza B viruses. Science. 2012 Sep 14; 337(6100):1343-8.

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W?thrich M, Hung CY, Gern BH, Pick-Jacobs JC, Galles KJ, Filutowicz HI, Cole GT, Klein BS. A TCR transgenic mouse reactive with multiple systemic dimorphic fungi. J Immunol. 2011 Aug 01; 187(3):1421-31.

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Sharma J, Mishra BB, Li Q, Teale JM. TLR4-dependent activation of inflammatory cytokine response in macrophages by Francisella elongation factor Tu. Cell Immunol. 2011; 269(2):69-73.

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Hartman IZ, Kim A, Cotter RJ, Walter K, Dalai SK, Boronina T, Griffith W, Lanar DE, Schwenk R, Krzych U, Cole RN, Sadegh-Nasseri S. A reductionist cell-free major histocompatibility complex class II antigen processing system identifies immunodominant epitopes. Nat Med. 2010 Nov; 16(11):1333-40.

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