Protein Isoforms

"Protein Isoforms" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Different forms of a protein that may be produced from different GENES, or from the same gene by ALTERNATIVE SPLICING.

Descriptor ID	D020033
MeSH Number(s)	D12.776.800
Concept/Terms	Protein Isoforms Protein Isoforms Isoforms, Protein Isoforms Splice Variants, Protein Splice Variants, Protein Variants, Protein Splice Protein Splice Variants

Below are MeSH descriptors whose meaning is more general than "Protein Isoforms".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Protein Isoforms [D12.776.800]

Below are MeSH descriptors whose meaning is related to "Protein Isoforms".

Below are MeSH descriptors whose meaning is more specific than "Protein Isoforms".

Protein Isoforms
Isoenzymes

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Protein Isoforms" by people in this website by year, and whether "Protein Isoforms" was a major or minor topic of these publications.

Bar chart showing 114 publications over 27 distinct years, with a maximum of 8 publications in 2002 and 2004 and 2009

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	0	1	1
1999	0	3	3
2000	0	2	2
2001	0	7	7
2002	2	6	8
2003	1	4	5
2004	1	7	8
2005	1	6	7
2006	0	6	6
2007	0	2	2
2008	1	3	4
2009	2	6	8
2010	1	4	5
2011	0	3	3
2012	0	5	5
2013	2	4	6
2014	0	2	2
2015	0	3	3
2016	0	6	6
2017	0	2	2
2018	0	5	5
2019	1	1	2
2020	0	3	3
2021	0	3	3
2022	0	1	1
2023	0	4	4
2024	0	3	3

Below are the most recent publications written about "Protein Isoforms" by people in Profiles.

Cordero Padilla K, Monefeldt GA, Guev?rez Gal?n A, Marrero HG, Lloret-Torres ME, Vel?zquez-Marrero C. BK ZERO isoform HEK293 stably transfected cell lines differing 3'UTRs to assess miR-9 regulation. PLoS One. 2024; 19(3):e0298966.

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Rodriguez D, Church KA, Pietramale AN, Cardona SM, Vanegas D, Rorex C, Leary MC, Muzzio IA, Nash KR, Cardona AE. Fractalkine isoforms differentially regulate microglia-mediated inflammation and enhance visual function in the diabetic retina. J Neuroinflammation. 2024 Feb 04; 21(1):42.

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Mazuca LG, Mohl JE. ISOGlyP: O-Glycosylation Site Prediction Using Peptide Sequences and GALNTs. Methods Mol Biol. 2024; 2763:237-247.

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Murphy MR, Ramadei A, Doymaz A, Varriano S, Natelson DM, Yu A, Aktas S, Mazzeo M, Mazzeo M, Zakusilo G, Kleiman FE. Long non-coding RNA generated from CDKN1A gene by alternative polyadenylation regulates p21 expression during DNA damage response. Nucleic Acids Res. 2023 Nov 27; 51(21):11911-11926.

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Ramirez E, Ganegamage SK, Min S, Patel H, Ogunware A, Plascencia-Villa G, Alnakhala H, Shimanaka K, Tripathi A, Wang KW, Zhu X, Rochet JC, Kuo MH, Counts SE, Perry G, Dettmer U, Lasagna-Reeves CA, Fortin JS. Evaluation of N- and O-Linked Indole Triazines for a Dual Effect on a-Synuclein and Tau Aggregation. ACS Chem Neurosci. 2023 11 01; 14(21):3913-3927.

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Wang Z, Sharda N, Omtri RS, Li L, Kandimalla KK. Amyloid-Beta Peptides 40 and 42 Employ Distinct Molecular Pathways for Cell Entry and Intracellular Transit at the Blood-Brain Barrier Endothelium. Mol Pharmacol. 2023 Nov; 104(5):203-213.

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Acu?a ML, Garc?a-Morin A, Orozco-Sep?lveda R, Ontiveros C, Flores A, Diaz AV, Guti?rrez-Zubiate I, Patil AR, Alvarado LA, Roy S, Russell WK, Rosas-Acosta G. Alternative splicing of the SUMO1/2/3 transcripts affects cellular SUMOylation and produces functionally distinct SUMO protein isoforms. Sci Rep. 2023 02 09; 13(1):2309.

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Hardwick SA, Hu W, Joglekar A, Fan L, Collier PG, Foord C, Balacco J, Lanjewar S, Sampson MM, Koopmans F, Prjibelski AD, Mikheenko A, Belchikov N, Jarroux J, Lucas AB, Palkovits M, Luo W, Milner TA, Ndhlovu LC, Smit AB, Trojanowski JQ, Lee VMY, Fedrigo O, Sloan SA, Tomb?cz D, Ross ME, Jarvis E, Boldogkoi Z, Gan L, Tilgner HU. Single-nuclei isoform RNA sequencing unlocks barcoded exon connectivity in frozen brain tissue. Nat Biotechnol. 2022 07; 40(7):1082-1092.

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Frankum R, Jameson TSO, Knight BA, Stephens FB, Wall BT, Donlon TA, Torigoe T, Willcox BJ, Willcox DC, Allsopp RC, Harries LW. Extreme longevity variants at the FOXO3 locus may moderate FOXO3 isoform levels. Geroscience. 2022 04; 44(2):1129-1140.

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Sabiu S, Idowu K. An insight on the nature of biochemical interactions between glycyrrhizin, myricetin and CYP3A4 isoform. J Food Biochem. 2022 03; 46(3):e13831.

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