The deubiquitinase CYLD targets Smad7 protein to regulate transforming growth factor ? (TGF-?) signaling and the development of regulatory T cells.

Zhao Y, Thornton AM, Kinney MC, Ma CA, Spinner JJ, Fuss IJ, Shevach EM, Jain A. The deubiquitinase CYLD targets Smad7 protein to regulate transforming growth factor ? (TGF-?) signaling and the development of regulatory T cells. J Biol Chem. 2011 Nov 25; 286(47):40520-30.

View in: PubMed

subject areas

Animals
CD4-Positive T-Lymphocytes
Cysteine Endopeptidases
Forkhead Transcription Factors
Gene Knockout Techniques
Hela Cells
Humans
Interleukin-2 Receptor alpha Subunit
Lymph Nodes
MAP Kinase Kinase Kinases
MAP Kinase Signaling System
Mice
p38 Mitogen-Activated Protein Kinases
Promoter Regions, Genetic
Protein Binding
Signal Transduction
Smad7 Protein
T-Lymphocytes, Regulatory
Transforming Growth Factor beta
Ubiquitination

authors with profiles

Angela M. Thornton

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