p38 Mitogen-Activated Protein Kinases

"p38 Mitogen-Activated Protein Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A mitogen-activated protein kinase subfamily that regulates a variety of cellular processes including CELL GROWTH PROCESSES; CELL DIFFERENTIATION; APOPTOSIS; and cellular responses to INFLAMMATION. The P38 MAP kinases are regulated by CYTOKINE RECEPTORS and can be activated in response to bacterial pathogens.

Descriptor ID	D048051
MeSH Number(s)	D08.811.913.696.620.682.700.567.843 D12.644.360.450.835 D12.776.476.450.835
Concept/Terms	p38 Mitogen-Activated Protein Kinases p38 Mitogen-Activated Protein Kinases p38 Mitogen Activated Protein Kinases p38 MAP Kinase MAP Kinase, p38 p38 MAPK MAPK, p38 p38 SAPK Mitogen-Activated Protein Kinase p38 Mitogen Activated Protein Kinase p38 p38 Protein Kinase Protein Kinase, p38

Below are MeSH descriptors whose meaning is more general than "p38 Mitogen-Activated Protein Kinases".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Transferases [D08.811.913]
Phosphotransferases [D08.811.913.696]
Phosphotransferases (Alcohol Group Acceptor) [D08.811.913.696.620]
Protein Kinases [D08.811.913.696.620.682]
Protein-Serine-Threonine Kinases [D08.811.913.696.620.682.700]
Mitogen-Activated Protein Kinases [D08.811.913.696.620.682.700.567]
p38 Mitogen-Activated Protein Kinases [D08.811.913.696.620.682.700.567.843]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intracellular Signaling Peptides and Proteins [D12.644.360]
Mitogen-Activated Protein Kinases [D12.644.360.450]
p38 Mitogen-Activated Protein Kinases [D12.644.360.450.835]
Proteins [D12.776]
Intracellular Signaling Peptides and Proteins [D12.776.476]
Mitogen-Activated Protein Kinases [D12.776.476.450]
p38 Mitogen-Activated Protein Kinases [D12.776.476.450.835]

Below are MeSH descriptors whose meaning is related to "p38 Mitogen-Activated Protein Kinases".

Below are MeSH descriptors whose meaning is more specific than "p38 Mitogen-Activated Protein Kinases".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "p38 Mitogen-Activated Protein Kinases" by people in this website by year, and whether "p38 Mitogen-Activated Protein Kinases" was a major or minor topic of these publications.

Bar chart showing 79 publications over 24 distinct years, with a maximum of 7 publications in 2016

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	0	1	1
2000	0	2	2
2001	0	3	3
2002	0	4	4
2003	0	4	4
2004	1	4	5
2005	3	2	5
2006	0	4	4
2007	2	2	4
2008	0	2	2
2009	2	3	5
2010	0	5	5
2011	1	5	6
2012	1	2	3
2013	3	1	4
2014	0	3	3
2015	1	3	4
2016	2	5	7
2017	0	1	1
2018	0	1	1
2019	0	1	1
2020	0	2	2
2021	1	1	2
2022	0	1	1

Below are the most recent publications written about "p38 Mitogen-Activated Protein Kinases" by people in Profiles.

Liu Y, Liu R, Huang L, Zuo G, Dai J, Gao L, Shi H, Fang Y, Lu Q, Okada T, Wang Z, Hu X, Lenahan C, Tang J, Xiao J, Zhang JH. Inhibition of Prostaglandin E2 Receptor EP3 Attenuates Oxidative Stress and Neuronal Apoptosis Partially by Modulating p38MAPK/FOXO3/Mul1/Mfn2 Pathway after Subarachnoid Hemorrhage in Rats. Oxid Med Cell Longev. 2022; 2022:7727616.

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Thakur V, Alcoreza N, Delgado M, Joddar B, Chattopadhyay M. Cardioprotective Effect of Glycyrrhizin on Myocardial Remodeling in Diabetic Rats. Biomolecules. 2021 04 13; 11(4).

View in: PubMed
Walker RR, Gallegos KM, Bratton MR, Lemieux KP, Zhang K, Wang G, Davidson AM, Tilghman SL. Acquisition of Letrozole Resistance Through Activation of the p38/MAPK Signaling Cascade. Anticancer Res. 2021 Feb; 41(2):583-599.

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Jimenez T, Friedman T, Vadgama J, Singh V, Tucker A, Collazo J, Sinha S, Hikim AS, Singh R, Pervin S. Nicotine Synergizes with High-Fat Diet to Induce an Anti-Inflammatory Microenvironment to Promote Breast Tumor Growth. Mediators Inflamm. 2020; 2020:5239419.

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Chen X, Hao A, Li X, Ye K, Zhao C, Yang H, Ma H, Hu L, Zhao Z, Hu L, Ye F, Sun Q, Zhang H, Wang H, Yao X, Fang Z. Activation of JNK and p38 MAPK Mediated by ZDHHC17 Drives Glioblastoma Multiforme Development and Malignant Progression. Theranostics. 2020; 10(3):998-1015.

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Sampath C, Sprouse JC, Freeman ML, Gangula PR. Activation of Nrf2 attenuates delayed gastric emptying in obesity induced diabetic (T2DM) female mice. Free Radic Biol Med. 2019 05 01; 135:132-143.

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Chen S, Zhao L, Sherchan P, Ding Y, Yu J, Nowrangi D, Tang J, Xia Y, Zhang JH. Activation of melanocortin receptor 4 with RO27-3225 attenuates neuroinflammation through AMPK/JNK/p38 MAPK pathway after intracerebral hemorrhage in mice. J Neuroinflammation. 2018 Apr 11; 15(1):106.

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Chung SS, Adekoya D, Enenmoh I, Clarke O, Wang P, Sarkyssian M, Wu Y, Vadgama JV. Salinomycin Abolished STAT3 and STAT1 Interactions and Reduced Telomerase Activity in Colorectal Cancer Cells. Anticancer Res. 2017 02; 37(2):445-453.

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Russell-Puleri S, Dela Paz NG, Adams D, Chattopadhyay M, Cancel L, Ebong E, Orr AW, Frangos JA, Tarbell JM. Fluid shear stress induces upregulation of COX-2 and PGI2 release in endothelial cells via a pathway involving PECAM-1, PI3K, FAK, and p38. Am J Physiol Heart Circ Physiol. 2017 Mar 01; 312(3):H485-H500.

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Tang K, Pasqua T, Biswas A, Mahata S, Tang J, Tang A, Bandyopadhyay GK, Sinha-Hikim AP, Chi NW, Webster NJ, Corti A, Mahata SK. Muscle injury, impaired muscle function and insulin resistance in Chromogranin A-knockout mice. J Endocrinol. 2017 02; 232(2):137-153.

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