E2F1 Transcription Factor
"E2F1 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An E2F transcription factor that interacts directly with RETINOBLASTOMA PROTEIN and CYCLIN A and activates GENETIC TRANSCRIPTION required for CELL CYCLE entry and DNA synthesis. E2F1 is involved in DNA REPAIR and APOPTOSIS.
| Descriptor ID |
D050687
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| MeSH Number(s) |
D12.644.360.024.328.049 D12.776.157.057.158.049 D12.776.476.024.420.049 D12.776.660.769.049 D12.776.930.211.500
|
| Concept/Terms |
E2F1 Transcription Factor- E2F1 Transcription Factor
- Transcription Factor, E2F1
- Transcription Factor E2F-1
- Transcription Factor E2F 1
- E2F Transcription Factor 1 Protein
- Retinoblastoma-Associated Protein 1
- Retinoblastoma Associated Protein 1
- Retinoblastoma Binding Protein 3
- E2F-1 Transcription Factor
- Transcription Factor, E2F-1
- Transcription Factor E2F1
|
Below are MeSH descriptors whose meaning is more general than "E2F1 Transcription Factor".
Below are MeSH descriptors whose meaning is more specific than "E2F1 Transcription Factor".
This graph shows the total number of publications written about "E2F1 Transcription Factor" by people in this website by year, and whether "E2F1 Transcription Factor" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 0 | 2 | 2 |
| 2015 | 0 | 1 | 1 |
| 2016 | 0 | 2 | 2 |
| 2017 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "E2F1 Transcription Factor" by people in Profiles.
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Kumar S, Tchounwou PB. Arsenic trioxide reduces the expression of E2F1, cyclin E, and phosphorylation of PI3K signaling molecules in acute leukemia cells. Environ Toxicol. 2021 Sep; 36(9):1785-1792.
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Zhao Y, Kang X, Gao F, Guzman A, Lau RP, Biniwale R, Wadehra M, Reemtsen B, Garg M, Halnon N, Quintero-Rivera F, Van Arsdell G, Coppola G, Nelson SF, Touma M. Gene-environment regulatory circuits of right ventricular pathology in tetralogy of fallot. J Mol Med (Berl). 2019 12; 97(12):1711-1722.
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Kundu N, Brekman A, Kim JY, Xiao G, Gao C, Bargonetti J. Estrogen-activated MDM2 disrupts mammary tissue architecture through a p53-independent pathway. Oncotarget. 2017 Jul 18; 8(29):47916-47930.
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Zhao Q, Zhao M, Parris AB, Xing Y, Yang X. Genistein targets the cancerous inhibitor of PP2A to induce growth inhibition and apoptosis in breast cancer cells. Int J Oncol. 2016 Sep; 49(3):1203-10.
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Liu D, Pattabiraman V, Bacanamwo M, Anderson LM. Iroquois homeobox transcription factor (Irx5) promotes G1/S-phase transition in vascular smooth muscle cells by CDK2-dependent activation. Am J Physiol Cell Physiol. 2016 08 01; 311(2):C179-89.
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Sosa-Garc?a B, V?zquez-Rivera V, Gonz?lez-Flores JN, Engel BE, Cress WD, Santiago-Cardona PG. The Retinoblastoma Tumor Suppressor Transcriptionally Represses Pak1 in Osteoblasts. PLoS One. 2015; 10(11):e0142406.
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Engel BE, Welsh E, Emmons MF, Santiago-Cardona PG, Cress WD. Expression of integrin alpha 10 is transcriptionally activated by pRb in mouse osteoblasts and is downregulated in multiple solid tumors. Cell Death Dis. 2013 Nov 28; 4:e938.
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Carey JP, Knowell AE, Chinaranagari S, Chaudhary J. Id4 promotes senescence and sensitivity to doxorubicin-induced apoptosis in DU145 prostate cancer cells. Anticancer Res. 2013 Oct; 33(10):4271-8.
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Tophkhane C, Yang SH, Jiang Y, Ma Z, Subramaniam D, Anant S, Yogosawa S, Sakai T, Liu WG, Edgerton S, Thor A, Yang X. p53 inactivation upregulates p73 expression through E2F-1 mediated transcription. PLoS One. 2012; 7(8):e43564.
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Shi Y, Yang S, Troup S, Lu X, Callaghan S, Park DS, Xing Y, Yang X. Resveratrol induces apoptosis in breast cancer cells by E2F1-mediated up-regulation of ASPP1. Oncol Rep. 2011 Jun; 25(6):1713-9.