E2F2 Transcription Factor
"E2F2 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An E2F transcription factor that interacts directly with RETINOBLASTOMA PROTEIN and CYCLIN A. E2F2 activates GENETIC TRANSCRIPTION required for CELL CYCLE entry and DNA synthesis.
| Descriptor ID |
D050703
|
| MeSH Number(s) |
D12.776.930.211.625
|
| Concept/Terms |
E2F2 Transcription Factor- E2F2 Transcription Factor
- Transcription Factor, E2F2
- Transcription Factor E2F-2
- E2F-2, Transcription Factor
- Transcription Factor E2F 2
- E2F Transcription Factor 2 Protein
- E2F2 Protein
- E2F-2 Protein
|
Below are MeSH descriptors whose meaning is more general than "E2F2 Transcription Factor".
Below are MeSH descriptors whose meaning is more specific than "E2F2 Transcription Factor".
This graph shows the total number of publications written about "E2F2 Transcription Factor" by people in this website by year, and whether "E2F2 Transcription Factor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
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Below are the most recent publications written about "E2F2 Transcription Factor" by people in Profiles.
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Timmers C, Sharma N, Opavsky R, Maiti B, Wu L, Wu J, Orringer D, Trikha P, Saavedra HI, Leone G. E2f1, E2f2, and E2f3 control E2F target expression and cellular proliferation via a p53-dependent negative feedback loop. Mol Cell Biol. 2007 Jan; 27(1):65-78.
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Sharma N, Timmers C, Trikha P, Saavedra HI, Obery A, Leone G. Control of the p53-p21CIP1 Axis by E2f1, E2f2, and E2f3 is essential for G1/S progression and cellular transformation. J Biol Chem. 2006 Nov 24; 281(47):36124-31.
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Jiang Y, Saavedra HI, Holloway MP, Leone G, Altura RA. Aberrant regulation of survivin by the RB/E2F family of proteins. J Biol Chem. 2004 Sep 24; 279(39):40511-20.
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Saavedra HI, Wu L, de Bruin A, Timmers C, Rosol TJ, Weinstein M, Robinson ML, Leone G. Specificity of E2F1, E2F2, and E2F3 in mediating phenotypes induced by loss of Rb. Cell Growth Differ. 2002 May; 13(5):215-25.
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Wu L, Timmers C, Maiti B, Saavedra HI, Sang L, Chong GT, Nuckolls F, Giangrande P, Wright FA, Field SJ, Greenberg ME, Orkin S, Nevins JR, Robinson ML, Leone G. The E2F1-3 transcription factors are essential for cellular proliferation. Nature. 2001 Nov 22; 414(6862):457-62.
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Wang H, Shao N, Ding QM, Cui J, Reddy ES, Rao VN. BRCA1 proteins are transported to the nucleus in the absence of serum and splice variants BRCA1a, BRCA1b are tyrosine phosphoproteins that associate with E2F, cyclins and cyclin dependent kinases. Oncogene. 1997 Jul 10; 15(2):143-57.