"Trypsin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A serine endopeptidase that is formed from TRYPSINOGEN in the pancreas. It is converted into its active form by ENTEROPEPTIDASE in the small intestine. It catalyzes hydrolysis of the carboxyl group of either arginine or lysine. EC 3.4.21.4.
| Descriptor ID |
D014357
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| MeSH Number(s) |
D08.811.277.656.300.760.895 D08.811.277.656.959.350.895
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Trypsin".
Below are MeSH descriptors whose meaning is more specific than "Trypsin".
This graph shows the total number of publications written about "Trypsin" by people in this website by year, and whether "Trypsin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 1 | 2 |
| 1997 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2003 | 1 | 1 | 2 |
| 2005 | 0 | 2 | 2 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 1 | 3 | 4 |
| 2009 | 0 | 2 | 2 |
| 2011 | 0 | 2 | 2 |
| 2013 | 0 | 1 | 1 |
| 2021 | 1 | 1 | 2 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Trypsin" by people in Profiles.
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Kumari N, Vaishnav MS, Srikanta S, Krishnaswamy PR, Bhat N. Exploring glycated sites in human serum albumin: impact of sample processing techniques on detection and analysis. Anal Methods. 2024 Aug 01; 16(30):5239-5247.
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Aboulouard S, Wisztorski M, Duhamel M, Saudemont P, Cardon T, Narducci F, Lemaire AS, Kobeissy F, Leblanc E, Fournier I, Salzet M. In-depth proteomics analysis of sentinel lymph nodes from individuals with endometrial cancer. Cell Rep Med. 2021 06 15; 2(6):100318.
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Denesyuk AI, Permyakov SE, Johnson MS, Permyakov EA, Uversky VN, Denessiouk K. Structural leitmotif and functional variations of the structural catalytic core in (chymo)trypsin-like serine/cysteine fold proteinases. Int J Biol Macromol. 2021 May 15; 179:601-609.
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Patterson RA, Juarez MT, Hermann A, Sasik R, Hardiman G, McGinnis W. Serine proteolytic pathway activation reveals an expanded ensemble of wound response genes in Drosophila. PLoS One. 2013; 8(4):e61773.
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Dumont Q, Donaldson DL, Griffith WP. Screening method for isopeptides from small ubiquitin-related modifier-conjugated proteins by ion mobility mass spectrometry. Anal Chem. 2011 Dec 15; 83(24):9638-42.
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Lundgaard GL, Daniels NE, Pyndiah S, Cassimere EK, Ahmed KM, Rodrigue A, Kihara D, Post CB, Sakamuro D. Identification of a novel effector domain of BIN1 for cancer suppression. J Cell Biochem. 2011 Oct; 112(10):2992-3001.
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Bustamante JJ, Gonzalez L, Carroll CA, Weintraub ST, Aguilar RM, Mu?oz J, Martinez AO, Haro LS. O-Glycosylated 24 kDa human growth hormone has a mucin-like biantennary disialylated tetrasaccharide attached at Thr-60. Proteomics. 2009 Jul; 9(13):3474-88.
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Nakayasu ES, Yashunsky DV, Nohara LL, Torrecilhas AC, Nikolaev AV, Almeida IC. GPIomics: global analysis of glycosylphosphatidylinositol-anchored molecules of Trypanosoma cruzi. Mol Syst Biol. 2009; 5:261.
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Bhattacharjee H, Choudhury R, Rosen BP. Role of conserved aspartates in the ArsA ATPase. Biochemistry. 2008 Jul 08; 47(27):7218-27.
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Jiang X, Han G, Feng S, Jiang X, Ye M, Yao X, Zou H. Automatic validation of phosphopeptide identifications by the MS2/MS3 target-decoy search strategy. J Proteome Res. 2008 Apr; 7(4):1640-9.