JAK3, STAT, and MAPK signaling pathways as novel molecular targets for the tyrphostin AG-490 regulation of IL-2-mediated T cell response.

Wang LH, Kirken RA, Erwin RA, Yu CR, Farrar WL. JAK3, STAT, and MAPK signaling pathways as novel molecular targets for the tyrphostin AG-490 regulation of IL-2-mediated T cell response. J Immunol. 1999 Apr 01; 162(7):3897-904.

View in: PubMed

subject areas

Adaptor Proteins, Signal Transducing
Adaptor Proteins, Vesicular Transport
Binding Sites
Calcium-Calmodulin-Dependent Protein Kinases
Cell Line
DNA
DNA-Binding Proteins
Enzyme Activation
Enzyme Inhibitors
Interleukin-2
Janus Kinase 3
Lymphocyte Activation
Milk Proteins
Phosphorylation
Phosphotyrosine
Proteins
Protein-Tyrosine Kinases
Receptors, Interleukin-2
RNA, Messenger
Shc Signaling Adaptor Proteins
Signal Transduction
STAT1 Transcription Factor
STAT3 Transcription Factor
STAT5 Transcription Factor
T-Lymphocytes
Trans-Activators
Tyrphostins

authors with profiles

Robert Kirken

RCMI CC is supported by the National Institute on Minority Health and Health Disparities, National Institutes of Health (NIH), through Grant Number U24MD015970. The contents of this site are solely the responsibility of the authors and do not necessarily represent the official views of the NIH

For technical support please contact support