"Tyrphostins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of synthetic protein tyrosine kinase inhibitors. They selectively inhibit receptor autophosphorylation and are used to study receptor function.
| Descriptor ID |
D020032
|
| MeSH Number(s) |
D02.455.426.559.389.150.795 D02.626.886 D03.633.100.857.885
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Tyrphostins".
Below are MeSH descriptors whose meaning is more specific than "Tyrphostins".
This graph shows the total number of publications written about "Tyrphostins" by people in this website by year, and whether "Tyrphostins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 2 | 0 | 2 |
| 2000 | 1 | 1 | 2 |
| 2001 | 1 | 2 | 3 |
| 2002 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Tyrphostins" by people in Profiles.
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Zhou AL, Swaminathan SK, Salian VS, Wang L, Curran GL, Min HK, Lowe VJ, Kandimalla KK. Insulin Signaling Differentially Regulates the Trafficking of Insulin and Amyloid Beta Peptides at the Blood-Brain Barrier. Mol Pharm. 2024 May 06; 21(5):2176-2186.
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Henderson VM, Hawsawi O, Burton LJ, Campbell T, Trice K, Dougan J, Howard SM, Odero-Marah VA. Cancer-bone microenvironmental interactions promotes STAT3 signaling. Mol Carcinog. 2019 08; 58(8):1349-1361.
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Pang J, Peng J, Matei N, Yang P, Kuai L, Wu Y, Chen L, Vitek MP, Li F, Sun X, Zhang JH, Jiang Y. Apolipoprotein E Exerts a Whole-Brain Protective Property by Promoting M1? Microglia Quiescence After Experimental Subarachnoid Hemorrhage in Mice. Transl Stroke Res. 2018 12; 9(6):654-668.
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Krafft PR, McBride D, Rolland WB, Lekic T, Flores JJ, Zhang JH. a7 Nicotinic Acetylcholine Receptor Stimulation Attenuates Neuroinflammation through JAK2-STAT3 Activation in Murine Models of Intracerebral Hemorrhage. Biomed Res Int. 2017; 2017:8134653.
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Chang HC, Yang YR, Wang PS, Kuo CH, Wang RY. Effects of insulin-like growth factor 1 on muscle atrophy and motor function in rats with brain ischemia. Chin J Physiol. 2010 Oct 31; 53(5):337-48.
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Shi Z, Tiwari AK, Shukla S, Robey RW, Kim IW, Parmar S, Bates SE, Si QS, Goldblatt CS, Abraham I, Fu LW, Ambudkar SV, Chen ZS. Inhibiting the function of ABCB1 and ABCG2 by the EGFR tyrosine kinase inhibitor AG1478. Biochem Pharmacol. 2009 Mar 01; 77(5):781-93.
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Ogunwobi OO, Beales IL. Leptin stimulates the proliferation of human oesophageal adenocarcinoma cells via HB-EGF and Tgfalpha mediated transactivation of the epidermal growth factor receptor. Br J Biomed Sci. 2008; 65(3):121-7.
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Beales IL, Ogunwobi O. Glycine-extended gastrin inhibits apoptosis in colon cancer cells via separate activation of Akt and JNK pathways. Mol Cell Endocrinol. 2006 Mar 09; 247(1-2):140-9.
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Millena AC, Reddy SC, Bowling GH, Khan SA. Autocrine regulation of steroidogenic function of Leydig cells by transforming growth factor-alpha. Mol Cell Endocrinol. 2004 Sep 30; 224(1-2):29-39.
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Turbov JM, Twaddle GM, Yang X, Liu NM, Murthy S. Effects of receptor tyrosine kinase inhibitor A47 on estrogen and growth factor-dependent breast cancer cell proliferation and apoptosis in vitro. J Surg Oncol. 2002 Jan; 79(1):17-29.