bcl-X Protein

"bcl-X Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A member of the bcl-2 protein family that plays a role in the regulation of APOPTOSIS and is a regulatory subunit for PROTEIN PHOSPHATASE 1. Two major isoforms of the protein exist due to ALTERNATIVE SPLICING of the BCL2L1 mRNA and are referred to as Bcl-XS and Bcl-XL.

Descriptor ID	D051020
MeSH Number(s)	D12.644.360.075.718.937 D12.776.476.075.718.875
Concept/Terms	bcl-X Protein bcl-X Protein bcl X Protein bcl2-Like 1 Protein bcl2 Like 1 Protein bcl2L1 Protein bcl-XS Protein bcl-XS Protein bcl XS Protein bcl-Xshort Protein bcl Xshort Protein bcl-X(S) Protein bcl-Xalpha Protein bcl-Xalpha Protein bcl Xalpha Protein bcl-Xa Protein bcl Xa Protein bcl-Xbeta Protein bcl-Xbeta Protein bcl Xbeta Protein bcl-Xb Protein bcl Xb Protein bcl-x(beta) Protein bcl-XL Protein bcl-XL Protein bcl XL Protein bcl-Xlong Protein bcl Xlong Protein bcl-X(L) Protein

Below are MeSH descriptors whose meaning is more general than "bcl-X Protein".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intracellular Signaling Peptides and Proteins [D12.644.360]
Apoptosis Regulatory Proteins [D12.644.360.075]
Proto-Oncogene Proteins c-bcl-2 [D12.644.360.075.718]
bcl-X Protein [D12.644.360.075.718.937]
Proteins [D12.776]
Intracellular Signaling Peptides and Proteins [D12.776.476]
Apoptosis Regulatory Proteins [D12.776.476.075]
Proto-Oncogene Proteins c-bcl-2 [D12.776.476.075.718]
bcl-X Protein [D12.776.476.075.718.875]

Below are MeSH descriptors whose meaning is related to "bcl-X Protein".

Below are MeSH descriptors whose meaning is more specific than "bcl-X Protein".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "bcl-X Protein" by people in this website by year, and whether "bcl-X Protein" was a major or minor topic of these publications.

Bar chart showing 20 publications over 12 distinct years, with a maximum of 2 publications in 2002 and 2004 and 2005 and 2007 and 2008 and 2011 and 2013 and 2017

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	0	1	1
2002	0	2	2
2004	0	2	2
2005	0	2	2
2007	1	1	2
2008	0	2	2
2009	0	1	1
2010	0	1	1
2011	0	2	2
2013	1	1	2
2016	0	1	1
2017	0	2	2

Below are the most recent publications written about "bcl-X Protein" by people in Profiles.

Chowdhury R, Gales D, Valenzuela P, Miller S, Yehualaeshet T, Manne U, Francia G, Samuel T. Bromoethylindole (BEI-9) redirects NF-?B signaling induced by camptothecin and TNFa to promote cell death in colon cancer cells. Apoptosis. 2017 Dec; 22(12):1553-1563.

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Chowdhury I, Branch A, Mehrabi S, Ford BD, Thompson WE. Gonadotropin-Dependent Neuregulin-1 Signaling Regulates Female Rat Ovarian Granulosa Cell Survival. Endocrinology. 2017 10 01; 158(10):3647-3660.

View in: PubMed
Wang H, Li M, Hung CY, Sinha M, Lee LM, Wiesner DL, LeBert V, Lerksuthirat T, Galles K, Suresh M, DeFranco AL, Lowell CA, Klein BS, W?thrich M. MyD88 Shapes Vaccine Immunity by Extrinsically Regulating Survival of CD4+ T Cells during the Contraction Phase. PLoS Pathog. 2016 08; 12(8):e1005787.

View in: PubMed
Chowdhury I, Thompson WE, Welch C, Thomas K, Matthews R. Prohibitin (PHB) inhibits apoptosis in rat granulosa cells (GCs) through the extracellular signal-regulated kinase 1/2 (ERK1/2) and the Bcl family of proteins. Apoptosis. 2013 Dec; 18(12):1513-25.

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Hao T, Rockwell P. Signaling through the vascular endothelial growth factor receptor VEGFR-2 protects hippocampal neurons from mitochondrial dysfunction and oxidative stress. Free Radic Biol Med. 2013 Oct; 63:421-31.

View in: PubMed
Gordy LE, Bezbradica JS, Flyak AI, Spencer CT, Dunkle A, Sun J, Stanic AK, Boothby MR, He YW, Zhao Z, Van Kaer L, Joyce S. IL-15 regulates homeostasis and terminal maturation of NKT cells. J Immunol. 2011 Dec 15; 187(12):6335-45.

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Mart?nez-Montemayor MM, Acevedo RR, Otero-Franqui E, Cubano LA, Dharmawardhane SF. Ganoderma lucidum (Reishi) inhibits cancer cell growth and expression of key molecules in inflammatory breast cancer. Nutr Cancer. 2011; 63(7):1085-94.

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Koyama M, Izutani Y, Goda AE, Matsui TA, Horinaka M, Tomosugi M, Fujiwara J, Nakamura Y, Wakada M, Yogosawa S, Sowa Y, Sakai T. Histone deacetylase inhibitors and 15-deoxy-Delta12,14-prostaglandin J2 synergistically induce apoptosis. Clin Cancer Res. 2010 Apr 15; 16(8):2320-32.

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Kajiya M, Shiba H, Fujita T, Takeda K, Uchida Y, Kawaguchi H, Kitagawa M, Takata T, Kurihara H. Brain-derived neurotrophic factor protects cementoblasts from serum starvation-induced cell death. J Cell Physiol. 2009 Dec; 221(3):696-706.

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Papa L, Rockwell P. Persistent mitochondrial dysfunction and oxidative stress hinder neuronal cell recovery from reversible proteasome inhibition. Apoptosis. 2008 Apr; 13(4):588-99.

View in: PubMed

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