Granulosa Cells

"Granulosa Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Supporting cells for the developing female gamete in the OVARY. They are derived from the coelomic epithelial cells of the gonadal ridge. Granulosa cells form a single layer around the OOCYTE in the primordial ovarian follicle and advance to form a multilayered cumulus oophorus surrounding the OVUM in the Graafian follicle. The major functions of granulosa cells include the production of steroids and LH receptors (RECEPTORS, LH).

Descriptor ID	D006107
MeSH Number(s)	A05.360.319.114.630.535.200 A06.407.312.497.535.300 A11.382.812 A11.436.329
Concept/Terms	Granulosa Cells Granulosa Cells Cell, Granulosa Cells, Granulosa Granulosa Cell

Below are MeSH descriptors whose meaning is more general than "Granulosa Cells".

Anatomy [A]
Urogenital System [A05]
Genitalia [A05.360]
Genitalia, Female [A05.360.319]
Adnexa Uteri [A05.360.319.114]
Ovary [A05.360.319.114.630]
Ovarian Follicle [A05.360.319.114.630.535]
Granulosa Cells [A05.360.319.114.630.535.200]
Endocrine System [A06]
Endocrine Glands [A06.407]
Gonads [A06.407.312]
Ovary [A06.407.312.497]
Ovarian Follicle [A06.407.312.497.535]
Granulosa Cells [A06.407.312.497.535.300]
Cells [A11]
Endocrine Cells [A11.382]
Granulosa Cells [A11.382.812]
Epithelial Cells [A11.436]
Granulosa Cells [A11.436.329]

Below are MeSH descriptors whose meaning is related to "Granulosa Cells".

Below are MeSH descriptors whose meaning is more specific than "Granulosa Cells".

Granulosa Cells
Cumulus Cells

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Granulosa Cells" by people in this website by year, and whether "Granulosa Cells" was a major or minor topic of these publications.

Bar chart showing 27 publications over 17 distinct years, with a maximum of 4 publications in 2016

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1999	1	0	1
2002	1	0	1
2003	1	0	1
2004	1	1	2
2005	1	0	1
2006	2	0	2
2008	1	0	1
2010	2	0	2
2011	2	0	2
2012	1	2	3
2013	1	0	1
2016	3	1	4
2017	1	1	2
2018	0	1	1
2021	1	0	1
2022	0	1	1
2024	0	1	1

Below are the most recent publications written about "Granulosa Cells" by people in Profiles.

Sun X, Qin N, Cao S, Wang S, Sun Y, Ou Y, Yan C, Ma C, Zhao J, Xu R, Mishra B. Novel insights into the regulation of NF2/SWH signaling in granulosa cells of prehierarchical follicle development in hen ovary. Poult Sci. 2026 Mar; 105(3):106375.

View in: PubMed
Singh A, Tripathi R, Gupta RK, Rashid R, Jha RK. Gonadotropin upregulates intraovarian calpains-1 and -2 during ovarian follicular recruitment in the SD rat model. Reprod Biol. 2024 Jun; 24(2):100862.

View in: PubMed
Banerjee S, Mishra S, Xu W, Thompson WE, Chowdhury I. Neuregulin-1 signaling regulates cytokines and chemokines expression and secretion in granulosa cell. J Ovarian Res. 2022 Jul 26; 15(1):86.

View in: PubMed
Sun X, Niu X, Qin N, Shan X, Zhao J, Ma C, Xu R, Mishra B. Novel insights into the regulation of LATS2 kinase in prehierarchical follicle development via the Hippo pathway in hen ovary. Poult Sci. 2021 Dec; 100(12):101454.

View in: PubMed
Hattori K, Orisaka M, Fukuda S, Tajima K, Yamazaki Y, Mizutani T, Yoshida Y. Luteinizing Hormone Facilitates Antral Follicular Maturation and Survival via Thecal Paracrine Signaling in Cattle. Endocrinology. 2018 06 01; 159(6):2337-2347.

View in: PubMed
Chowdhury I, Branch A, Mehrabi S, Ford BD, Thompson WE. Gonadotropin-Dependent Neuregulin-1 Signaling Regulates Female Rat Ovarian Granulosa Cell Survival. Endocrinology. 2017 10 01; 158(10):3647-3660.

View in: PubMed
Uslu B, Dioguardi CC, Haynes M, Miao DQ, Kurus M, Hoffman G, Johnson J. Quantifying growing versus non-growing ovarian follicles in the mouse. J Ovarian Res. 2017 Jan 13; 10(1):3.

View in: PubMed
Wilson K, Park J, Curry TE, Mishra B, Gossen J, Taniuchi I, Jo M. Core Binding Factor-? Knockdown Alters Ovarian Gene Expression and Function in the Mouse. Mol Endocrinol. 2016 Jul; 30(7):733-47.

View in: PubMed
Chowdhury I, Thomas K, Zeleznik A, Thompson WE. Prohibitin regulates the FSH signaling pathway in rat granulosa cell differentiation. J Mol Endocrinol. 2016 05; 56(4):325-36.

View in: PubMed
Conca Dioguardi C, Uslu B, Haynes M, Kurus M, Gul M, Miao DQ, De Santis L, Ferrari M, Bellone S, Santin A, Giulivi C, Hoffman G, Usdin K, Johnson J. Granulosa cell and oocyte mitochondrial abnormalities in a mouse model of fragile X primary ovarian insufficiency. Mol Hum Reprod. 2016 06; 22(6):384-96.

View in: PubMed

People

Explore

Similar Concepts

Top Journals