Endothelial Cells

"Endothelial Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Highly specialized EPITHELIAL CELLS that line the HEART; BLOOD VESSELS; and lymph vessels, forming the ENDOTHELIUM. They are polygonal in shape and joined together by TIGHT JUNCTIONS. The tight junctions allow for variable permeability to specific macromolecules that are transported across the endothelial layer.

Descriptor ID	D042783
MeSH Number(s)	A11.436.275
Concept/Terms	Endothelial Cells Endothelial Cells Cell, Endothelial Cells, Endothelial Endothelial Cell Vascular Endothelial Cells Vascular Endothelial Cells Cell, Vascular Endothelial Cells, Vascular Endothelial Endothelial Cell, Vascular Endothelial Cells, Vascular Vascular Endothelial Cell Capillary Endothelial Cells Capillary Endothelial Cells Capillary Endothelial Cell Cell, Capillary Endothelial Cells, Capillary Endothelial Endothelial Cell, Capillary Endothelial Cells, Capillary Lymphatic Endothelial Cells Lymphatic Endothelial Cells Cell, Lymphatic Endothelial Cells, Lymphatic Endothelial Endothelial Cell, Lymphatic Endothelial Cells, Lymphatic Lymphatic Endothelial Cell

Below are MeSH descriptors whose meaning is more general than "Endothelial Cells".

Anatomy [A]
Cells [A11]
Epithelial Cells [A11.436]
Endothelial Cells [A11.436.275]

Below are MeSH descriptors whose meaning is more specific than "Endothelial Cells".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Endothelial Cells" by people in this website by year, and whether "Endothelial Cells" was a major or minor topic of these publications.

Bar chart showing 251 publications over 23 distinct years, with a maximum of 20 publications in 2011

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2003	6	1	7
2004	6	4	10
2005	3	4	7
2006	10	6	16
2007	10	5	15
2008	8	7	15
2009	8	7	15
2010	6	2	8
2011	12	8	20
2012	7	5	12
2013	9	9	18
2014	5	6	11
2015	7	5	12
2016	10	2	12
2017	6	4	10
2018	6	1	7
2019	5	1	6
2020	3	4	7
2021	3	7	10
2022	6	10	16
2023	3	6	9
2024	2	2	4
2025	4	0	4

Below are the most recent publications written about "Endothelial Cells" by people in Profiles.

Asante J, Barger SW. Impact of P-glycoprotein substrates on transendothelial transport of amyloid-? peptide in an in vitro model. Neuroscience. 2026 May 14; 602:104-111.

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Irei JS, Hirayama K, Boisvert WA. Emerging regulators of endothelial lipid metabolism in atherosclerosis. Curr Opin Lipidol. 2026 Jun 01; 37(3):113-119.

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Salian VS, Curan GL, Lowe VJ, Tang X, Kalari KR, Kandimalla KK. Elucidating molecular mechanisms governing tumor necrosis factor-alpha-mediated regulation of amyloid beta 42 uptake in blood-brain barrier endothelial cells. Mol Pharmacol. 2026 Jan; 108(1):100088.

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Bai Y, Ren H, Leng S, Yuan M, Jiang Y, Zhang S, Wang Y, Ju M, Wang Z, Xi W, Xu L, Zheng B, Li D, Huo X, Zhu T, Zhang B, Shen L, Zhang Y, Jiang W, Zhang JH, Han B, Yao H. CD8+GZMK+CD27+CCR7+ T cells mobilized by splenic sympathetic nerves aggravate brain ischemia?reperfusion injury via CCL19-positive endothelial cells. Cell Mol Immunol. 2025 Sep; 22(9):1061-1076.

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Wahab R, Keshavarz A, Azam Z, Islam T, Hasan MM, Zhang X, Alobaida A, Rana M, Choi JU, Alam F, Kim IS, Byun Y, McCarty JH, Nickel NP, Roy S, Al-Hilal TA. Microfluidic captured patient-derived circulating endothelial cells identify novel targets of pulmonary arterial hypertension. Biomaterials. 2025 Dec; 323:123429.

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Wang L, Curran GL, Zhong R, Xue Z, Veerareddy V, Thieschafer J, Min PH, Li L, Lowe VJ, Kandimalla KK. Amyloid beta peptides inhibit glucose transport at the blood-brain barrier by disrupting the insulin-AKT pathway. J Cereb Blood Flow Metab. 2025 Oct; 45(10):1961-1979.

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Cai Z, Zhang Y, He L, Cui M, Zhang W, E L, Yang H, Ling Q, Hoffmann PR, He J, Gou S, Liu F, Huang Z. Methylseleninic Acid Elevating the Nrf2-GPX4 Axis Relieves Endothelial Dysfunction and Ferroptosis Induced by Arsenic Exposure. J Agric Food Chem. 2025 Mar 26; 73(12):7445-7455.

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Ferrini MG, Abraham A, Mill?n R, Graciano L, Eleswarapu SV, Rajfer J. Nutraceutical COMP-4 confers protection against endothelial dysfunction through the eNOS/iNOS-NO-cGMP pathway. PLoS One. 2025; 20(2):e0316798.

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Salian VS, Tang X, Thompson KJ, Curan GL, Lowe VJ, Li L, Kalari KR, Kandimalla KK. Molecular Mechanisms Underlying Amyloid Beta Peptide Mediated Upregulation of Vascular Cell Adhesion Molecule-1 in Alzheimer Disease. J Pharmacol Exp Ther. 2024 Nov 19; 391(3):430-440.

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Wang Z, Zhong R, Curran GL, Min P, Lowe VJ, Li L, Kandimalla KK. High-Density Lipoprotein Mimetic Peptide 4F Reduces Toxic Amyloid-Beta Exposure to the Blood-Brain Barrier Endothelium in Alzheimer's Disease Transgenic Mice. Mol Pharm. 2024 Nov 04; 21(11):5661-5671.

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