bcl-2-Associated X Protein

"bcl-2-Associated X Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A member of the Bcl-2 protein family and homologous partner of C-BCL-2 PROTO-ONCOGENE PROTEIN. It regulates the release of CYTOCHROME C and APOPTOSIS INDUCING FACTOR from the MITOCHONDRIA. Several isoforms of BCL2-associated X protein occur due to ALTERNATIVE SPLICING of the mRNA for this protein.

Descriptor ID	D051028
MeSH Number(s)	D12.644.360.075.718.400 D12.776.476.075.718.400
Concept/Terms	bcl-2-Associated X Protein bcl-2-Associated X Protein Protein, bcl-2-Associated X X Protein, bcl-2-Associated bcl 2 Associated X Protein Bax Apoptosis Regulator Protein Bax Protein bcl2-Associated X Protein bcl2 Associated X Protein bcl2-Associated X Protein Isoform beta bcl2-Associated X Protein Isoform beta bcl2 Associated X Protein Isoform beta Bax-beta Protein Bax beta Protein bcl2-Associated X Protein Isoform sigma bcl2-Associated X Protein Isoform sigma bcl2 Associated X Protein Isoform sigma Bax-sigma Protein Bax sigma Protein bcl2-Associated X Protein Isoform omega bcl2-Associated X Protein Isoform omega bcl2 Associated X Protein Isoform omega Bax-omega Protein Bax omega Protein bcl2-Associated X Protein Isoform alpha bcl2-Associated X Protein Isoform alpha bcl2 Associated X Protein Isoform alpha Bax-alpha Protein Bax alpha Protein bcl2-Associated X Protein Isoform delta bcl2-Associated X Protein Isoform delta bcl2 Associated X Protein Isoform delta Bax-delta Protein Bax delta Protein

Below are MeSH descriptors whose meaning is more general than "bcl-2-Associated X Protein".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intracellular Signaling Peptides and Proteins [D12.644.360]
Apoptosis Regulatory Proteins [D12.644.360.075]
Proto-Oncogene Proteins c-bcl-2 [D12.644.360.075.718]
bcl-2-Associated X Protein [D12.644.360.075.718.400]
Proteins [D12.776]
Intracellular Signaling Peptides and Proteins [D12.776.476]
Apoptosis Regulatory Proteins [D12.776.476.075]
Proto-Oncogene Proteins c-bcl-2 [D12.776.476.075.718]
bcl-2-Associated X Protein [D12.776.476.075.718.400]

Below are MeSH descriptors whose meaning is related to "bcl-2-Associated X Protein".

Below are MeSH descriptors whose meaning is more specific than "bcl-2-Associated X Protein".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "bcl-2-Associated X Protein" by people in this website by year, and whether "bcl-2-Associated X Protein" was a major or minor topic of these publications.

Bar chart showing 56 publications over 19 distinct years, with a maximum of 6 publications in 2007

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	0	1	1
2001	0	1	1
2002	0	5	5
2003	0	2	2
2004	0	3	3
2005	0	2	2
2006	1	1	2
2007	2	4	6
2008	2	2	4
2009	0	4	4
2010	0	2	2
2011	0	4	4
2012	0	2	2
2014	0	4	4
2015	0	3	3
2016	0	4	4
2017	0	2	2
2019	0	3	3
2021	0	2	2

Below are the most recent publications written about "bcl-2-Associated X Protein" by people in Profiles.

Cao JY, Wang B, Tang TT, Wen Y, Li ZL, Feng ST, Wu M, Liu D, Yin D, Ma KL, Tang RN, Wu QL, Lan HY, Lv LL, Liu BC. Exosomal miR-125b-5p deriving from mesenchymal stem cells promotes tubular repair by suppression of p53 in ischemic acute kidney injury. Theranostics. 2021; 11(11):5248-5266.

View in: PubMed
Ghoneum MH, El Sayed NS. Protective Effect of Biobran/MGN-3 against Sporadic Alzheimer's Disease Mouse Model: Possible Role of Oxidative Stress and Apoptotic Pathways. Oxid Med Cell Longev. 2021; 2021:8845064.

View in: PubMed
Badr El-Din NK, Areida SK, Ahmed KO, Ghoneum M. Arabinoxylan rice bran (MGN-3/Biobran) enhances radiotherapy in animals bearing Ehrlich ascites carcinoma?. J Radiat Res. 2019 Nov 22; 60(6):747-758.

View in: PubMed
Menezes ESB, Badial PR, El Debaky H, Husna AU, Ugur MR, Kaya A, Topper E, Bulla C, Grant KE, Bolden-Tiller O, Moura AA, Memili E. Sperm miR-15a and miR-29b are associated with bull fertility. Andrologia. 2020 Feb; 52(1):e13412.

View in: PubMed
Gutierrez DA, DeJesus RE, Contreras L, Rodriguez-Palomares IA, Villanueva PJ, Balderrama KS, Monterroza L, Larragoity M, Varela-Ramirez A, Aguilera RJ. A new pyridazinone exhibits potent cytotoxicity on human cancer cells via apoptosis and poly-ubiquitinated protein accumulation. Cell Biol Toxicol. 2019 12; 35(6):503-519.

View in: PubMed
Pajarillo E, Johnson J, Kim J, Karki P, Son DS, Aschner M, Lee E. 17?-estradiol and tamoxifen protect mice from manganese-induced dopaminergic neurotoxicity. Neurotoxicology. 2018 03; 65:280-288.

View in: PubMed
Zhao M, Howard EW, Guo Z, Parris AB, Yang X. p53 pathway determines the cellular response to alcohol-induced DNA damage in MCF-7 breast cancer cells. PLoS One. 2017; 12(4):e0175121.

View in: PubMed
Burton LJ, Rivera M, Hawsawi O, Zou J, Hudson T, Wang G, Zhang Q, Cubano L, Boukli N, Odero-Marah V. Muscadine Grape Skin Extract Induces an Unfolded Protein Response-Mediated Autophagy in Prostate Cancer Cells: A TMT-Based Quantitative Proteomic Analysis. PLoS One. 2016; 11(10):e0164115.

View in: PubMed
Martinez L, Thames E, Kim J, Chaudhuri G, Singh R, Pervin S. Increased sensitivity of African American triple negative breast cancer cells to nitric oxide-induced mitochondria-mediated apoptosis. BMC Cancer. 2016 07 29; 16:559.

View in: PubMed
Badr El-Din NK, Abdel Fattah SM, Pan D, Tolentino L, Ghoneum M. Chemopreventive Activity of MGN-3/Biobran Against Chemical Induction of Glandular Stomach Carcinogenesis in Rats and Its Apoptotic Effect in Gastric Cancer Cells. Integr Cancer Ther. 2016 12; 15(4):NP26-NP34.

View in: PubMed

People

Explore

Similar Concepts

Top Journals