bcl-2 Homologous Antagonist-Killer Protein
"bcl-2 Homologous Antagonist-Killer Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A multi-domain mitochondrial membrane protein and member of the bcl-2 Protein family. Bak protein interacts with TUMOR SUPPRESSOR PROTEIN P53 and promotes APOPTOSIS.
| Descriptor ID |
D050998
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| MeSH Number(s) |
D12.644.360.075.718.750 D12.776.476.075.718.425
|
| Concept/Terms |
bcl-2 Homologous Antagonist-Killer Protein- bcl-2 Homologous Antagonist-Killer Protein
- bcl 2 Homologous Antagonist Killer Protein
- bcl2 Homologous Antagonist-Killer Protein
- bcl2 Homologous Antagonist Killer Protein
- Bak Protein
|
Below are MeSH descriptors whose meaning is more general than "bcl-2 Homologous Antagonist-Killer Protein".
Below are MeSH descriptors whose meaning is more specific than "bcl-2 Homologous Antagonist-Killer Protein".
This graph shows the total number of publications written about "bcl-2 Homologous Antagonist-Killer Protein" by people in this website by year, and whether "bcl-2 Homologous Antagonist-Killer Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "bcl-2 Homologous Antagonist-Killer Protein" by people in Profiles.
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Mebratu YA, Leyva-Baca I, Wathelet MG, Lacey N, Chand HS, Choi AMK, Tesfaigzi Y. Bik reduces hyperplastic cells by increasing Bak and activating DAPk1 to juxtapose ER and mitochondria. Nat Commun. 2017 10 06; 8(1):803.
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Pietsch EC, Perchiniak E, Canutescu AA, Wang G, Dunbrack RL, Murphy ME. Oligomerization of BAK by p53 utilizes conserved residues of the p53 DNA binding domain. J Biol Chem. 2008 Jul 25; 283(30):21294-304.
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Thota CS, Reed LC, Yallampalli C. Effects of parathyroid hormone like hormone (PTHLH) antagonist, PTHLH(7-34), on fetoplacental development and growth during midgestation in rats. Biol Reprod. 2005 Dec; 73(6):1191-8.
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Wang Z, Cuddy M, Samuel T, Welsh K, Schimmer A, Hanaii F, Houghten R, Pinilla C, Reed JC. Cellular, biochemical, and genetic analysis of mechanism of small molecule IAP inhibitors. J Biol Chem. 2004 Nov 12; 279(46):48168-76.
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Kitamura Y, Shimohama S, Kamoshima W, Ota T, Matsuoka Y, Nomura Y, Smith MA, Perry G, Whitehouse PJ, Taniguchi T. Alteration of proteins regulating apoptosis, Bcl-2, Bcl-x, Bax, Bak, Bad, ICH-1 and CPP32, in Alzheimer's disease. Brain Res. 1998 Jan 12; 780(2):260-9.