STAT2 Transcription Factor
"STAT2 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A signal transducer and activator of transcription that mediates cellular responses to TYPE I INTERFERONS. Stat2 protein is associated constitutively with INTERFERON REGULATORY FACTOR-9. After PHOSPHORYLATION Stat2 forms the IFN-STIMULATED GENE FACTOR 3 COMPLEX to regulate expression of target GENES.
| Descriptor ID |
D050795
|
| MeSH Number(s) |
D12.644.360.024.303.500.750 D12.644.360.024.342.200 D12.776.157.057.061.500.750 D12.776.157.057.186.200 D12.776.260.513.249.750 D12.776.476.024.386.500.750 D12.776.476.024.430.200 D12.776.930.354.249.750 D12.776.930.840.200
|
| Concept/Terms |
STAT2 Transcription Factor- STAT2 Transcription Factor
- Transcription Factor, STAT2
- Transcription Factor STAT2
- Factor STAT2, Transcription
- STAT2 Protein
- Signal Transducer and Activator of Transcription 2
|
Below are MeSH descriptors whose meaning is more general than "STAT2 Transcription Factor".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Peptides [D12.644]
- Intracellular Signaling Peptides and Proteins [D12.644.360]
- Adaptor Proteins, Signal Transducing [D12.644.360.024]
- Interferon-Stimulated Gene Factor 3 [D12.644.360.024.303]
- Interferon-Stimulated Gene Factor 3, alpha Subunit [D12.644.360.024.303.500]
- STAT2 Transcription Factor [D12.644.360.024.303.500.750]
- STAT Transcription Factors [D12.644.360.024.342]
- STAT2 Transcription Factor [D12.644.360.024.342.200]
- Proteins [D12.776]
- Carrier Proteins [D12.776.157]
- Adaptor Proteins, Signal Transducing [D12.776.157.057]
- Interferon-Stimulated Gene Factor 3 [D12.776.157.057.061]
- Interferon-Stimulated Gene Factor 3, alpha Subunit [D12.776.157.057.061.500]
- STAT2 Transcription Factor [D12.776.157.057.061.500.750]
- STAT Transcription Factors [D12.776.157.057.186]
- STAT2 Transcription Factor [D12.776.157.057.186.200]
- DNA-Binding Proteins [D12.776.260]
- Interferon-Stimulated Gene Factor 3 [D12.776.260.513]
- Interferon-Stimulated Gene Factor 3, alpha Subunit [D12.776.260.513.249]
- STAT2 Transcription Factor [D12.776.260.513.249.750]
- Intracellular Signaling Peptides and Proteins [D12.776.476]
- Adaptor Proteins, Signal Transducing [D12.776.476.024]
- Interferon-Stimulated Gene Factor 3 [D12.776.476.024.386]
- Interferon-Stimulated Gene Factor 3, alpha Subunit [D12.776.476.024.386.500]
- STAT2 Transcription Factor [D12.776.476.024.386.500.750]
- STAT Transcription Factors [D12.776.476.024.430]
- STAT2 Transcription Factor [D12.776.476.024.430.200]
- Transcription Factors [D12.776.930]
- Interferon-Stimulated Gene Factor 3 [D12.776.930.354]
- Interferon-Stimulated Gene Factor 3, alpha Subunit [D12.776.930.354.249]
- STAT2 Transcription Factor [D12.776.930.354.249.750]
- STAT Transcription Factors [D12.776.930.840]
- STAT2 Transcription Factor [D12.776.930.840.200]
Below are MeSH descriptors whose meaning is more specific than "STAT2 Transcription Factor".
This graph shows the total number of publications written about "STAT2 Transcription Factor" by people in this website by year, and whether "STAT2 Transcription Factor" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "STAT2 Transcription Factor" by people in Profiles.
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Su HC, Ma CT, Lin CF, Wu HT, Chuang YH, Chen LJ, Tsao CW. The acid sphingomyelinase inhibitors block interferon-a-induced serotonin uptake via a COX-2/Akt/ERK/STAT-dependent pathway in T cells. Int Immunopharmacol. 2011 Nov; 11(11):1823-31.
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Gunning PT, Katt WP, Glenn M, Siddiquee K, Siddique K, Kim JS, Jove R, Sebti SM, Turkson J, Hamilton AD. Isoform selective inhibition of STAT1 or STAT3 homo-dimerization via peptidomimetic probes: structural recognition of STAT SH2 domains. Bioorg Med Chem Lett. 2007 Apr 01; 17(7):1875-8.
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Turkson J. STAT proteins as novel targets for cancer drug discovery. Expert Opin Ther Targets. 2004 Oct; 8(5):409-22.
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Subramaniam SV, Cooper RS, Adunyah SE. Evidence for the involvement of JAK/STAT pathway in the signaling mechanism of interleukin-17. Biochem Biophys Res Commun. 1999 Aug 19; 262(1):14-9.