STAT6 Transcription Factor

"STAT6 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A signal transducer and activator of transcription that mediates cellular responses to INTERLEUKIN-4. Stat6 has been shown to partner with NF-KAPPA B and CCAAT-ENHANCER-BINDING PROTEINS to regulate GENETIC TRANSCRIPTION of interleukin-4 responsive GENES.

Descriptor ID	D050800
MeSH Number(s)	D12.644.360.024.342.600 D12.776.157.057.186.600 D12.776.476.024.430.600 D12.776.930.840.600
Concept/Terms	STAT6 Transcription Factor STAT6 Transcription Factor Transcription Factor, STAT6 STAT6 Protein Signal Transducer and Activator of Transcription 6

Below are MeSH descriptors whose meaning is more general than "STAT6 Transcription Factor".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intracellular Signaling Peptides and Proteins [D12.644.360]
Adaptor Proteins, Signal Transducing [D12.644.360.024]
STAT Transcription Factors [D12.644.360.024.342]
STAT6 Transcription Factor [D12.644.360.024.342.600]
Proteins [D12.776]
Carrier Proteins [D12.776.157]
Adaptor Proteins, Signal Transducing [D12.776.157.057]
STAT Transcription Factors [D12.776.157.057.186]
STAT6 Transcription Factor [D12.776.157.057.186.600]
Intracellular Signaling Peptides and Proteins [D12.776.476]
Adaptor Proteins, Signal Transducing [D12.776.476.024]
STAT Transcription Factors [D12.776.476.024.430]
STAT6 Transcription Factor [D12.776.476.024.430.600]
Transcription Factors [D12.776.930]
STAT Transcription Factors [D12.776.930.840]
STAT6 Transcription Factor [D12.776.930.840.600]

Below are MeSH descriptors whose meaning is related to "STAT6 Transcription Factor".

Below are MeSH descriptors whose meaning is more specific than "STAT6 Transcription Factor".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "STAT6 Transcription Factor" by people in this website by year, and whether "STAT6 Transcription Factor" was a major or minor topic of these publications.

Bar chart showing 14 publications over 12 distinct years, with a maximum of 2 publications in 2000 and 2018

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	0	1	1
1997	0	1	1
1998	0	1	1
2000	0	2	2
2002	0	1	1
2004	0	1	1
2007	0	1	1
2008	0	1	1
2010	1	0	1
2013	1	0	1
2018	0	2	2
2020	0	1	1

Below are the most recent publications written about "STAT6 Transcription Factor" by people in Profiles.

Yu S, Balasubramanian I, Laubitz D, Tong K, Bandyopadhyay S, Lin X, Flores J, Singh R, Liu Y, Macazana C, Zhao Y, B?guet-Crespel F, Patil K, Midura-Kiela MT, Wang D, Yap GS, Ferraris RP, Wei Z, Bonder EM, H?ggblom MM, Zhang L, Douard V, Verzi MP, Cadwell K, Kiela PR, Gao N. Paneth Cell-Derived Lysozyme Defines the Composition of Mucolytic Microbiota and the Inflammatory Tone of the Intestine. Immunity. 2020 08 18; 53(2):398-416.e8.

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Takeshima H, Horie M, Mikami Y, Makita K, Miyashita N, Matsuzaki H, Noguchi S, Urushiyama H, Hiraishi Y, Mitani A, Borok Z, Nagase T, Yamauchi Y. CISH is a negative regulator of IL-13-induced CCL26 production in lung fibroblasts. Allergol Int. 2019 Jan; 68(1):101-109.

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Makita K, Mikami Y, Matsuzaki H, Miyashita N, Takeshima H, Noguchi S, Horie M, Urushiyama H, Iikura M, Hojo M, Nagase T, Yamauchi Y. Mechanism of Periostin Production in Human Bronchial Smooth Muscle Cells. Int Arch Allergy Immunol. 2018; 175(1-2):26-35.

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Youngren SR, Tekade RK, Gustilo B, Hoffmann PR, Chougule MB. STAT6 siRNA matrix-loaded gelatin nanocarriers: formulation, characterization, and ex vivo proof of concept using adenocarcinoma cells. Biomed Res Int. 2013; 2013:858946.

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Mishra BB, Gundra UM, Teale JM. STAT6?/? mice exhibit decreased cells with alternatively activated macrophage phenotypes and enhanced disease severity in murine neurocysticercosis. J Neuroimmunol. 2011 Mar; 232(1-2):26-34.

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Hui GS, Hashimoto CN. Adjuvant formulations possess differing efficacy in the potentiation of antibody and cell mediated responses to a human malaria vaccine under selective immune genes knockout environment. Int Immunopharmacol. 2008 Jul; 8(7):1012-22.

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Hoffmann PR, Jourdan-Le Saux C, Hoffmann FW, Chang PS, Bollt O, He Q, Tam EK, Berry MJ. A role for dietary selenium and selenoproteins in allergic airway inflammation. J Immunol. 2007 Sep 01; 179(5):3258-67.

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Turkson J. STAT proteins as novel targets for cancer drug discovery. Expert Opin Ther Targets. 2004 Oct; 8(5):409-22.

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Wang Y, Malabarba MG, Nagy ZS, Kirken RA. Interleukin 4 regulates phosphorylation of serine 756 in the transactivation domain of Stat6. Roles for multiple phosphorylation sites and Stat6 function. J Biol Chem. 2004 Jun 11; 279(24):25196-203.

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Chen XP, Losman JA, Cowan S, Donahue E, Fay S, Vuong BQ, Nawijn MC, Capece D, Cohan VL, Rothman P. Pim serine/threonine kinases regulate the stability of Socs-1 protein. Proc Natl Acad Sci U S A. 2002 Feb 19; 99(4):2175-80.

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