Fibroblast growth factor 2 applied to the optic nerve after axotomy up-regulates BDNF and TrkB in ganglion cells by activating the ERK and PKA signaling pathways.

Soto I, Rosenthal JJ, Blagburn JM, Blanco RE. Fibroblast growth factor 2 applied to the optic nerve after axotomy up-regulates BDNF and TrkB in ganglion cells by activating the ERK and PKA signaling pathways. J Neurochem. 2006 Jan; 96(1):82-96.

View in: PubMed

subject areas

Animals
Axotomy
Blotting, Western
Brain-Derived Neurotrophic Factor
Cyclic AMP Response Element-Binding Protein
Cyclic AMP-Dependent Protein Kinases
DNA, Complementary
Enzyme Activation
Exons
Extracellular Signal-Regulated MAP Kinases
Fibroblast Growth Factor 2
Immunohistochemistry
In Situ Hybridization
Mitogen-Activated Protein Kinases
Optic Nerve
Rana pipiens
Receptor, trkB
Retinal Ganglion Cells
Reverse Transcriptase Polymerase Chain Reaction
Signal Transduction
Up-Regulation

authors with profiles

Jonathan M. Blagburn
Rosa E. Blanco
Joshua Rosenthal

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