Brain-Derived Neurotrophic Factor

"Brain-Derived Neurotrophic Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A member of the nerve growth factor family of trophic factors. In the brain BDNF has a trophic action on retinal, cholinergic, and dopaminergic neurons, and in the peripheral nervous system it acts on both motor and sensory neurons. (From Kendrew, The Encyclopedia of Molecular Biology, 1994)

Descriptor ID	D019208
MeSH Number(s)	D12.644.276.860.100 D12.776.467.860.100 D12.776.631.600.100 D23.529.850.100
Concept/Terms	Brain-Derived Neurotrophic Factor Brain-Derived Neurotrophic Factor Brain Derived Neurotrophic Factor Factor, Brain-Derived Neurotrophic Neurotrophic Factor, Brain-Derived BDNF

Below are MeSH descriptors whose meaning is more general than "Brain-Derived Neurotrophic Factor".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intercellular Signaling Peptides and Proteins [D12.644.276]
Nerve Growth Factors [D12.644.276.860]
Brain-Derived Neurotrophic Factor [D12.644.276.860.100]
Proteins [D12.776]
Intercellular Signaling Peptides and Proteins [D12.776.467]
Nerve Growth Factors [D12.776.467.860]
Brain-Derived Neurotrophic Factor [D12.776.467.860.100]
Nerve Tissue Proteins [D12.776.631]
Nerve Growth Factors [D12.776.631.600]
Brain-Derived Neurotrophic Factor [D12.776.631.600.100]
Biological Factors [D23]
Intercellular Signaling Peptides and Proteins [D23.529]
Nerve Growth Factors [D23.529.850]
Brain-Derived Neurotrophic Factor [D23.529.850.100]

Below are MeSH descriptors whose meaning is related to "Brain-Derived Neurotrophic Factor".

Below are MeSH descriptors whose meaning is more specific than "Brain-Derived Neurotrophic Factor".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Brain-Derived Neurotrophic Factor" by people in this website by year, and whether "Brain-Derived Neurotrophic Factor" was a major or minor topic of these publications.

Bar chart showing 50 publications over 20 distinct years, with a maximum of 5 publications in 2012 and 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1999	0	1	1
2002	1	0	1
2003	1	0	1
2005	2	0	2
2007	1	2	3
2008	2	1	3
2009	1	0	1
2010	1	2	3
2011	1	2	3
2012	4	1	5
2013	2	3	5
2014	1	3	4
2015	0	3	3
2016	1	1	2
2017	0	3	3
2018	1	0	1
2019	0	2	2
2020	0	1	1
2022	2	2	4
2024	1	1	2

Below are the most recent publications written about "Brain-Derived Neurotrophic Factor" by people in Profiles.

Allsopp RC, Hern?ndez LM, Taylor MK. The Val66Met variant of brain-derived neurotrophic factor is linked to reduced telomere length in a military population: a pilot study. Sci Rep. 2024 11 06; 14(1):27013.

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Lloret-Torres ME, Barreto-Estrada JL. LF-DBS of the ventral striatum shortens persistence for morphine place preference and modulates BDNF expression in the hippocampus. Behav Brain Res. 2025 Feb 04; 477:115300.

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Carrico AW, Cherenack EM, Flentje A, Moskowitz JT, Asam K, Ghanooni D, Chavez JV, Neilands TB, Dilworth SE, Rubin LH, Gouse H, Fuchs D, Paul RH, Aouizerat BE. A positive affect intervention alters leukocyte DNA methylation in sexual minority men with HIV who use methamphetamine. Brain Behav Immun. 2024 Aug; 120:151-158.

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Allan NP, Yamamoto BY, Kunihiro BP, Nunokawa CKL, Rubas NC, Wells RK, Umeda L, Phankitnirundorn K, Torres A, Peres R, Takahashi E, Maunakea AK. Ketogenic Diet Induced Shifts in the Gut Microbiome Associate with Changes to Inflammatory Cytokines and Brain-Related miRNAs in Children with Autism Spectrum Disorder. Nutrients. 2024 May 07; 16(10).

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Cancel LM, Silas D, Bikson M, Tarbell JM. Direct current stimulation modulates gene expression in isolated astrocytes with implications for glia-mediated plasticity. Sci Rep. 2022 10 26; 12(1):17964.

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Frois T, Faria LO, Souza RP, da Silva Cunha AE, de Holanda Marinho Nogueira NG, Tavares Lim V, de Sousa Fortes L, de Miranda DM, Bertollo M, Albuquerque MR. Are COMT Val158Met (rs4680), DRD2 TaqIA (rs1800497), and BDNF Val66Met (rs6265) polymorphisms associated with executive functions performance at rest and during physical exercise? Physiol Behav. 2022 12 01; 257:113973.

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Cabral DF, Bigliassi M, Cattaneo G, Rundek T, Pascual-Leone A, Cahalin LP, Gomes-Osman J. Exploring the interplay between mechanisms of neuroplasticity and cardiovascular health in aging adults: A multiple linear regression analysis study. Auton Neurosci. 2022 11; 242:103023.

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Vukmanovic Nosrat I, Palacios JL, Kezian S, Luong G, Tran A, Vu K, Henson BS, Nosrat P, Lutfy K, Nosrat CA. Brain-derived neurotrophic factor overexpression in taste buds diminishes chemotherapy induced taste loss. Eur J Neurosci. 2022 10; 56(7):4967-4982.

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Giordano M, Trotta MC, Ciarambino T, D'Amico M, Galdiero M, Schettini F, Paternosto D, Salzillo M, Alfano R, Andreone V, Malatino LS, Biolo G, Paolisso G, Adinolfi LE. Circulating MiRNA-195-5p and -451a in Diabetic Patients with Transient and Acute Ischemic Stroke in the Emergency Department. Int J Mol Sci. 2020 Oct 15; 21(20).

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Harbuzariu A, Pitts S, Cespedes JC, Harp KO, Nti A, Shaw AP, Liu M, Stiles JK. Modelling heme-mediated brain injury associated with cerebral malaria in human brain cortical organoids. Sci Rep. 2019 12 16; 9(1):19162.

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