Optic Nerve

"Optic Nerve" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The 2nd cranial nerve which conveys visual information from the RETINA to the brain. The nerve carries the axons of the RETINAL GANGLION CELLS which sort at the OPTIC CHIASM and continue via the OPTIC TRACTS to the brain. The largest projection is to the lateral geniculate nuclei; other targets include the SUPERIOR COLLICULI and the SUPRACHIASMATIC NUCLEI. Though known as the second cranial nerve, it is considered part of the CENTRAL NERVOUS SYSTEM.

Descriptor ID	D009900
MeSH Number(s)	A08.800.800.120.680
Concept/Terms	Optic Nerve Optic Nerve Nerve, Optic Nerves, Optic Optic Nerves Nervus Opticus Opticus, Nervus Second Cranial Nerve Cranial Nerve, Second Cranial Nerves, Second Nerve, Second Cranial Nerves, Second Cranial Second Cranial Nerves Cranial Nerve II Cranial Nerve IIs Nerve II, Cranial Nerve IIs, Cranial

Below are MeSH descriptors whose meaning is more general than "Optic Nerve".

Anatomy [A]
Nervous System [A08]
Peripheral Nervous System [A08.800]
Peripheral Nerves [A08.800.800]
Cranial Nerves [A08.800.800.120]
Optic Nerve [A08.800.800.120.680]

Below are MeSH descriptors whose meaning is related to "Optic Nerve".

Below are MeSH descriptors whose meaning is more specific than "Optic Nerve".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Optic Nerve" by people in this website by year, and whether "Optic Nerve" was a major or minor topic of these publications.

Bar chart showing 19 publications over 15 distinct years, with a maximum of 2 publications in 2002 and 2012 and 2016 and 2017

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	1	0	1
2001	1	0	1
2002	1	1	2
2003	0	1	1
2005	1	0	1
2008	1	0	1
2009	1	0	1
2011	0	1	1
2012	2	0	2
2016	1	1	2
2017	2	0	2
2019	1	0	1
2020	1	0	1
2021	0	1	1
2025	0	1	1

Below are the most recent publications written about "Optic Nerve" by people in Profiles.

Demer JL, Clark RA, Suh SY, Giaconi JA, Nouri-Mahdavi K, Law SK, Bonelli L, Arnold AC, Quiros P, Coleman AL, Caprioli J. Eye Movements and the Intraorbital Subarachnoid Space: Potential Contribution of Altered Cerebrospinal Fluid Pumping in Optic Neuropathies. Invest Ophthalmol Vis Sci. 2025 Jan 02; 66(1):53.

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Ratanawongphaibul K, Tsikata E, Zemplenyi M, Lee H, Margeta MA, Ondeck CL, Kim J, Pan BX, Petrakos P, Coleman AL, Yu F, de Boer JF, Chen TC. Earlier Detection of Glaucoma Progression Using High-Density 3-Dimensional Spectral-Domain OCT Optic Nerve Volume Scans. Ophthalmol Glaucoma. 2021 Nov-Dec; 4(6):604-616.

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Clark RA, Suh SY, Caprioli J, Giaconi JA, Nouri-Mahdavi K, Law SK, Bonelli L, Coleman AL, Demer JL. Adduction-Induced Strain on the Optic Nerve in Primary Open Angle Glaucoma at Normal Intraocular Pressure. Curr Eye Res. 2021 04; 46(4):568-578.

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Demer JL, Clark RA, Suh SY, Giaconi JA, Nouri-Mahdavi K, Law SK, Bonelli L, Coleman AL, Caprioli J. Optic Nerve Traction During Adduction in Open Angle Glaucoma with Normal versus Elevated Intraocular Pressure. Curr Eye Res. 2020 02; 45(2):199-210.

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Demer JL, Clark RA, Suh SY, Giaconi JA, Nouri-Mahdavi K, Law SK, Bonelli L, Coleman AL, Caprioli J. Magnetic Resonance Imaging of Optic Nerve Traction During Adduction in Primary Open-Angle Glaucoma With Normal Intraocular Pressure. Invest Ophthalmol Vis Sci. 2017 08 01; 58(10):4114-4125.

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Pershad J, Taylor A, Hall MK, Klimo P. Imaging Strategies for Suspected Acute Cranial Shunt Failure: A Cost-Effectiveness Analysis. Pediatrics. 2017 Aug; 140(2).

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Duprey-D?az MV, Blagburn JM, Blanco RE. Exogenous Modulation of Retinoic Acid Signaling Affects Adult RGC Survival in the Frog Visual System after Optic Nerve Injury. PLoS One. 2016; 11(9):e0162626.

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Zhavoronkov A, Izumchenko E, Kanherkar RR, Teka M, Cantor C, Manaye K, Sidransky D, West MD, Makarev E, Csoka AB. Pro-fibrotic pathway activation in trabecular meshwork and lamina cribrosa is the main driving force of glaucoma. Cell Cycle. 2016 06 17; 15(12):1643-52.

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Duprey-D?az MV, Blagburn JM, Blanco RE. Changes in fibroblast growth factor-2 and FGF receptors in the frog visual system during optic nerve regeneration. J Chem Neuroanat. 2012 Dec; 46(1-2):35-44.

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Nouri-Mahdavi K, Mock D, Hosseini H, Bitrian E, Yu F, Afifi A, Coleman AL, Caprioli J. Pointwise rates of visual field progression cluster according to retinal nerve fiber layer bundles. Invest Ophthalmol Vis Sci. 2012 Apr 30; 53(4):2390-4.

View in: PubMed

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