"Complement Factor I" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A plasma serine proteinase that cleaves the alpha-chains of C3b and C4b in the presence of the cofactors COMPLEMENT FACTOR H and C4-binding protein, respectively. It is a 66-kDa glycoprotein that converts C3b to inactivated C3b (iC3b) followed by the release of two fragments, C3c (150-kDa) and C3dg (41-kDa). It was formerly called KAF, C3bINF, or enzyme 3b inactivator.
| Descriptor ID |
D017244
|
| MeSH Number(s) |
D08.811.277.656.300.760.210 D08.811.277.656.959.350.210 D12.776.124.486.274.920.325.210
|
| Concept/Terms |
Complement Factor I- Complement Factor I
- C4b-C3b-INA
- C4b C3b INA
- C3b Inactivator
- Inactivator, C3b
- C4bC3bINA
- Complement C4b-C3b Inactivator
- C4b-C3b Inactivator, Complement
- Complement C4b C3b Inactivator
- Inactivator, Complement C4b-C3b
- C3b-C4b Inactivator
- C3b C4b Inactivator
- Inactivator, C3b-C4b
- Complement 3b-Complement 4b Inactivator
- Complement 3b Complement 4b Inactivator
|
Below are MeSH descriptors whose meaning is more general than "Complement Factor I".
Below are MeSH descriptors whose meaning is more specific than "Complement Factor I".
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