Gene Knockdown Techniques

"Gene Knockdown Techniques" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The artificial induction of GENE SILENCING by the use of RNA INTERFERENCE to reduce the expression of a specific gene. It includes the use of DOUBLE-STRANDED RNA, such as SMALL INTERFERING RNA and RNA containing HAIRPIN LOOP SEQUENCE, and ANTI-SENSE OLIGONUCLEOTIDES.

Descriptor ID	D055785
MeSH Number(s)	E05.393.335.500
Concept/Terms	Gene Knockdown Techniques Gene Knockdown Techniques Gene Knockdown Technique Knockdown Technique, Gene Knockdown Techniques, Gene Technique, Gene Knockdown Techniques, Gene Knockdown Gene Knockdown Gene Knockdowns Knockdown, Gene Knockdowns, Gene Gene Knock-Down Gene Knock-Downs Knock-Down, Gene Knock-Downs, Gene Gene Knock-Down Techniques Gene Knock-Down Technique Knock-Down Technique, Gene Knock-Down Techniques, Gene Technique, Gene Knock-Down Techniques, Gene Knock-Down Gene Knock Down Gene Knock Downs Knock Down, Gene Knock Downs, Gene Gene Knock Down Techniques

Below are MeSH descriptors whose meaning is more general than "Gene Knockdown Techniques".

Analytical, Diagnostic and Therapeutic Techniques and Equipment [E]
Investigative Techniques [E05]
Genetic Techniques [E05.393]
Gene Targeting [E05.393.335]
Gene Knockdown Techniques [E05.393.335.500]

Below are MeSH descriptors whose meaning is related to "Gene Knockdown Techniques".

Below are MeSH descriptors whose meaning is more specific than "Gene Knockdown Techniques".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Gene Knockdown Techniques" by people in this website by year, and whether "Gene Knockdown Techniques" was a major or minor topic of these publications.

Bar chart showing 119 publications over 16 distinct years, with a maximum of 21 publications in 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2008	1	0	1
2009	1	1	2
2010	0	7	7
2011	0	6	6
2012	0	8	8
2013	0	21	21
2014	0	16	16
2015	0	11	11
2016	0	11	11
2017	0	6	6
2018	0	8	8
2019	0	8	8
2020	0	7	7
2021	0	5	5
2022	0	1	1
2024	0	1	1

Below are the most recent publications written about "Gene Knockdown Techniques" by people in Profiles.

Chuang TD, Ton N, Manrique N, Rysling S, Khorram O. Targeting the long non-coding RNA MIAT for the treatment of fibroids in an animal model. Clin Sci (Lond). 2024 Jun 19; 138(12):699-709.

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Rabelo-Fern?ndez RJ, Santiago-S?nchez GS, Sharma RK, Roche-Lima A, Carrion KC, Rivera RAN, Qui?ones-D?az BI, Rajasekaran S, Siddiqui J, Miles W, Rivera YS, Valiyeva F, Vivas-Mejia PE. Reduced RBPMS Levels Promote Cell Proliferation and Decrease Cisplatin Sensitivity in Ovarian Cancer Cells. Int J Mol Sci. 2022 Jan 04; 23(1).

View in: PubMed
Banu K, Lin Q, Basgen JM, Planoutene M, Wei C, Reghuvaran AC, Tian X, Shi H, Garzon F, Garzia A, Chun N, Cumpelik A, Santeusanio AD, Zhang W, Das B, Salem F, Li L, Ishibe S, Cantley LG, Kaufman L, Lemley KV, Ni Z, He JC, Murphy B, Menon MC. AMPK mediates regulation of glomerular volume and podocyte survival. JCI Insight. 2021 10 08; 6(19).

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Reddy D, Bhattacharya S, Shah S, Rashid M, Gupta S. DNA methylation mediated downregulation of histone H3 variant H3.3 affects cell proliferation contributing to the development of HCC. Biochim Biophys Acta Mol Basis Dis. 2022 01 01; 1868(1):166284.

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Kaushal JB, Shukla V, Sankhwar P, Jha RK, Dwivedi A. Targeted inhibition of TAK1 abrogates TGF?1 non-canonical signaling axis, NF?B/Smad7 inhibiting human endometriotic cells proliferation and inducing cell death involving autophagy. Cytokine. 2021 12; 148:155700.

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Luo QJ, Zhang J, Li P, Wang Q, Zhang Y, Roy-Chaudhuri B, Xu J, Kay MA, Zhang QC. RNA structure probing reveals the structural basis of Dicer binding and cleavage. Nat Commun. 2021 06 07; 12(1):3397.

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Baskaran P, Nazminia K, Frantz J, O'Neal J, Thyagarajan B. Mice lacking endogenous TRPV1 express reduced levels of thermogenic proteins and are susceptible to diet-induced obesity and metabolic dysfunction. FEBS Lett. 2021 07; 595(13):1768-1781.

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Mitra S, Muralidharan SV, Di Marco M, Juvvuna PK, Kosalai ST, Reischl S, Jachimowicz D, Subhash S, Raimondi I, Kurian L, Huarte M, Kogner P, Fischer M, Johnsen JI, Mondal T, Kanduri C. Subcellular Distribution of p53 by the p53-Responsive lncRNA NBAT1 Determines Chemotherapeutic Response in Neuroblastoma. Cancer Res. 2021 03 15; 81(6):1457-1471.

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Maan M, Agrawal NJ, Padmanabhan J, Leitzinger CC, Rivera-Rivera Y, Saavedra HI, Chellappan SP. Tank Binding Kinase 1 modulates spindle assembly checkpoint components to regulate mitosis in breast and lung cancer cells. Biochim Biophys Acta Mol Cell Res. 2021 03; 1868(3):118929.

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Dash S, Balasubramaniam M, Mart?nez-Rivera FJ, Godino A, Peck EG, Patnaik S, Suar M, Calipari ES, Nestler EJ, Villalta F, Dash C, Pandhare J. Cocaine-regulated microRNA miR-124 controls poly (ADP-ribose) polymerase-1 expression in neuronal cells. Sci Rep. 2020 07 08; 10(1):11197.

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