Gene Knock-In Techniques

"Gene Knock-In Techniques" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Techniques used to add in exogenous gene sequence such as mutated genes; REPORTER GENES, to study mechanisms of gene expression; or regulatory control sequences, to study effects of temporal changes to GENE EXPRESSION.

Descriptor ID	D055879
MeSH Number(s)	E05.393.335.249
Concept/Terms	Gene Knock-In Techniques Gene Knock-In Techniques Gene Knock-In Technique Knock-In Technique, Gene Knock-In Techniques, Gene Technique, Gene Knock-In Techniques, Gene Knock-In Gene Knock-In Gene Knock-Ins Knock-In, Gene Knock-Ins, Gene Gene Knock In Gene Knock Ins In, Gene Knock Ins, Gene Knock Knock In, Gene Knock Ins, Gene Gene Knock In Techniques

Below are MeSH descriptors whose meaning is more general than "Gene Knock-In Techniques".

Analytical, Diagnostic and Therapeutic Techniques and Equipment [E]
Investigative Techniques [E05]
Genetic Techniques [E05.393]
Gene Targeting [E05.393.335]
Gene Knock-In Techniques [E05.393.335.249]

Below are MeSH descriptors whose meaning is related to "Gene Knock-In Techniques".

Below are MeSH descriptors whose meaning is more specific than "Gene Knock-In Techniques".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Gene Knock-In Techniques" by people in this website by year, and whether "Gene Knock-In Techniques" was a major or minor topic of these publications.

Bar chart showing 13 publications over 8 distinct years, with a maximum of 3 publications in 2010

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2008	0	1	1
2009	0	2	2
2010	0	3	3
2011	0	1	1
2013	0	1	1
2015	0	1	1
2017	0	2	2
2019	1	1	2

Below are the most recent publications written about "Gene Knock-In Techniques" by people in Profiles.

Korecki AJ, Hickmott JW, Lam SL, Dreolini L, Mathelier A, Baker O, Kuehne C, Bonaguro RJ, Smith J, Tan CV, Zhou M, Goldowitz D, Deussing JM, Stewart AF, Wasserman WW, Holt RA, Simpson EM. Twenty-Seven Tamoxifen-Inducible iCre-Driver Mouse Strains for Eye and Brain, Including Seventeen Carrying a New Inducible-First Constitutive-Ready Allele. Genetics. 2019 04; 211(4):1155-1177.

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Liu M, Wang L, Gao J, Dong Q, Perry G, Ma X, Wang X. Inhibition of Calpain Protects Against Tauopathy in Transgenic P301S Tau Mice. J Alzheimers Dis. 2019; 69(4):1077-1087.

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Weems E, Singha UK, Smith JT, Chaudhuri M. The divergent N-terminal domain of Tim17 is critical for its assembly in the TIM complex in Trypanosoma brucei. Mol Biochem Parasitol. 2017 12; 218:4-15.

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Baba K, DeBruyne JP, Tosini G. Dopamine 2 Receptor Activation Entrains Circadian Clocks in Mouse Retinal Pigment Epithelium. Sci Rep. 2017 07 11; 7(1):5103.

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Laucho-Contreras ME, Polverino F, Gupta K, Taylor KL, Kelly E, Pinto-Plata V, Divo M, Ashfaq N, Petersen H, Stripp B, Pilon AL, Tesfaigzi Y, Celli BR, Owen CA. Protective role for club cell secretory protein-16 (CC16) in the development of COPD. Eur Respir J. 2015 Jun; 45(6):1544-56.

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Schmouth JF, Castellarin M, Laprise S, Banks KG, Bonaguro RJ, McInerny SC, Borretta L, Amirabbasi M, Korecki AJ, Portales-Casamar E, Wilson G, Dreolini L, Jones SJ, Wasserman WW, Goldowitz D, Holt RA, Simpson EM. Non-coding-regulatory regions of human brain genes delineated by bacterial artificial chromosome knock-in mice. BMC Biol. 2013 Oct 14; 11:106.

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Nagura H, Ishikawa Y, Kobayashi K, Takao K, Tanaka T, Nishikawa K, Tamura H, Shiosaka S, Suzuki H, Miyakawa T, Fujiyoshi Y, Doi T. Impaired synaptic clustering of postsynaptic density proteins and altered signal transmission in hippocampal neurons, and disrupted learning behavior in PDZ1 and PDZ2 ligand binding-deficient PSD-95 knockin mice. Mol Brain. 2012 Dec 26; 5:43.

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Wang J, Gusti V, Saraswati A, Lo DD. Convergent and divergent development among M cell lineages in mouse mucosal epithelium. J Immunol. 2011 Nov 15; 187(10):5277-85.

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Castanon-Cervantes O, Wu M, Ehlen JC, Paul K, Gamble KL, Johnson RL, Besing RC, Menaker M, Gewirtz AT, Davidson AJ. Dysregulation of inflammatory responses by chronic circadian disruption. J Immunol. 2010 Nov 15; 185(10):5796-805.

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Li F, Yan Y, Pieretti J, Feldman DA, Eckhardt LA. Comparison of identical and functional Igh alleles reveals a nonessential role for E? in somatic hypermutation and class-switch recombination. J Immunol. 2010 Nov 15; 185(10):6049-57.

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