"Caspase 10" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A long pro-domain caspase that contains a death effector domain in its pro-domain region. Activation of this enzyme can occur via the interaction of its N-terminal death effector domain with DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEINS. Caspase 10 plays a role in APOPTOSIS by cleaving and activating EFFECTOR CASPASES. Several isoforms of this protein exist due to multiple alternative splicing of its MESSENGER RNA.
| Descriptor ID |
D053455
|
| MeSH Number(s) |
D08.811.277.656.262.500.126.550.910 D08.811.277.656.300.200.126.550.910 D12.644.360.075.405.550.910 D12.776.476.075.405.550.910
|
| Concept/Terms |
Caspase 10a- Caspase 10a
- Mch4 Protease
- Protease, Mch4
- Caspase 10-a
- Caspase 10 a
|
Below are MeSH descriptors whose meaning is more general than "Caspase 10".
Below are MeSH descriptors whose meaning is more specific than "Caspase 10".
This graph shows the total number of publications written about "Caspase 10" by people in this website by year, and whether "Caspase 10" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
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Below are the most recent publications written about "Caspase 10" by people in Profiles.
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Yang S, Zhou Q, Yang X. Caspase-3 status is a determinant of the differential responses to genistein between MDA-MB-231 and MCF-7 breast cancer cells. Biochim Biophys Acta. 2007 Jun; 1773(6):903-11.
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Yang S, Thor AD, Edgerton S, Yang X. Caspase-3 mediated feedback activation of apical caspases in doxorubicin and TNF-alpha induced apoptosis. Apoptosis. 2006 Nov; 11(11):1987-97.