Excitatory Amino Acid Transporter 1
"Excitatory Amino Acid Transporter 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A glial type glutamate plasma membrane transporter protein found predominately in ASTROCYTES. It is also expressed in HEART and SKELETAL MUSCLE and in the PLACENTA.
| Descriptor ID |
D027341
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| MeSH Number(s) |
D12.776.157.530.200.249.500.500.500 D12.776.157.530.450.625.147.500 D12.776.157.530.562.374.781.500 D12.776.157.530.937.250.500.500 D12.776.543.585.200.249.500.500.500 D12.776.543.585.450.625.147.500 D12.776.543.585.562.374.781.500 D12.776.543.585.937.250.500.500
|
| Concept/Terms |
Excitatory Amino Acid Transporter 1- Excitatory Amino Acid Transporter 1
- SLC1A3 Transporter
- Transporter, SLC1A3
- EAAT-1 Excitatory Amino Acid Transporter
- EAAT 1 Excitatory Amino Acid Transporter
- Glutamate Aspartate Transporter 1
- GLAST-1 Glutamate Aspartate Transporter
- GLAST 1 Glutamate Aspartate Transporter
|
Below are MeSH descriptors whose meaning is more general than "Excitatory Amino Acid Transporter 1".
Below are MeSH descriptors whose meaning is more specific than "Excitatory Amino Acid Transporter 1".
This graph shows the total number of publications written about "Excitatory Amino Acid Transporter 1" by people in this website by year, and whether "Excitatory Amino Acid Transporter 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2017 | 2 | 0 | 2 |
| 2018 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Excitatory Amino Acid Transporter 1" by people in Profiles.
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Pajarillo E, Johnson J, Rizor A, Nyarko-Danquah I, Adinew G, Bornhorst J, Stiboller M, Schwerdtle T, Son DS, Aschner M, Lee E. Astrocyte-specific deletion of the transcription factor Yin Yang 1 in murine substantia nigra mitigates manganese-induced dopaminergic neurotoxicity. J Biol Chem. 2020 11 13; 295(46):15662-15676.
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Johnson J, Pajarillo E, Karki P, Kim J, Son DS, Aschner M, Lee E. Valproic acid attenuates manganese-induced reduction in expression of GLT-1 and GLAST with concomitant changes in murine dopaminergic neurotoxicity. Neurotoxicology. 2018 07; 67:112-120.
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Karki P, Hong P, Johnson J, Pajarillo E, Son DS, Aschner M, Lee EY. Arundic Acid Increases Expression and Function of Astrocytic Glutamate Transporter EAAT1 Via the ERK, Akt, and NF-?B Pathways. Mol Neurobiol. 2018 Jun; 55(6):5031-5046.
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Johnson J, Pajarillo EAB, Taka E, Reams R, Son DS, Aschner M, Lee E. Valproate and sodium butyrate attenuate manganese-decreased locomotor activity and astrocytic glutamate transporters expression in mice. Neurotoxicology. 2018 01; 64:230-239.
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Karki P, Kim C, Smith K, Son DS, Aschner M, Lee E. Transcriptional Regulation of the Astrocytic Excitatory Amino Acid Transporter 1 (EAAT1) via NF-?B and Yin Yang 1 (YY1). J Biol Chem. 2015 Sep 25; 290(39):23725-37.
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Karki P, Webb A, Zerguine A, Choi J, Son DS, Lee E. Mechanism of raloxifene-induced upregulation of glutamate transporters in rat primary astrocytes. Glia. 2014 Aug; 62(8):1270-83.