Interleukin-17

"Interleukin-17" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A proinflammatory cytokine produced primarily by T-LYMPHOCYTES or their precursors. Several subtypes of interleukin-17 have been identified, each of which is a product of a unique gene.

Descriptor ID	D020381
MeSH Number(s)	D12.644.276.374.465.517 D12.776.467.374.465.517 D23.529.374.465.517
Concept/Terms	Interleukin-17 Interleukin-17 Interleukin 17 CTLA-8 IL-17 Interleukin-17F Interleukin-17F Interleukin 17F IL-17F Cytokine ML-1 Cytokine ML 1 Interleukin-17C Interleukin-17C Interleukin 17C IL-17C Cytokine CX2 CX2, Cytokine Interleukin-17E Interleukin-17E Interleukin 17E Interleukin-25 Interleukin 25 IL-17E IL 17E Interleukin-17A Interleukin-17A Interleukin 17A Cytotoxic T lymphocyte-Associated Antigen 8 Cytotoxic T lymphocyte Associated Antigen 8 IL-17A CTLA8 Interleukin-17B Interleukin-17B Interleukin 17B IL-17B

Below are MeSH descriptors whose meaning is more general than "Interleukin-17".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intercellular Signaling Peptides and Proteins [D12.644.276]
Cytokines [D12.644.276.374]
Interleukins [D12.644.276.374.465]
Interleukin-17 [D12.644.276.374.465.517]
Proteins [D12.776]
Intercellular Signaling Peptides and Proteins [D12.776.467]
Cytokines [D12.776.467.374]
Interleukins [D12.776.467.374.465]
Interleukin-17 [D12.776.467.374.465.517]
Biological Factors [D23]
Intercellular Signaling Peptides and Proteins [D23.529]
Cytokines [D23.529.374]
Interleukins [D23.529.374.465]
Interleukin-17 [D23.529.374.465.517]

Below are MeSH descriptors whose meaning is related to "Interleukin-17".

Below are MeSH descriptors whose meaning is more specific than "Interleukin-17".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Interleukin-17" by people in this website by year, and whether "Interleukin-17" was a major or minor topic of these publications.

Bar chart showing 39 publications over 16 distinct years, with a maximum of 6 publications in 2015

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1999	2	0	2
2007	2	1	3
2008	1	0	1
2009	2	1	3
2010	2	2	4
2011	1	3	4
2012	2	3	5
2013	0	1	1
2014	0	1	1
2015	4	2	6
2016	1	2	3
2017	0	1	1
2018	1	0	1
2019	0	1	1
2022	0	1	1
2023	0	2	2

Below are the most recent publications written about "Interleukin-17" by people in Profiles.

Lu W, Huang J, Flores J, Li P, Wang W, Liu S, Zhang JH, Tang J. GW0742 reduces mast cells degranulation and attenuates neurological impairments via PPAR?/d/CD300a/SHP1 pathway after GMH in neonatal rats. Exp Neurol. 2024 02; 372:114615.

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Kotas ME, Patel NN, Cope EK, Gurrola JG, Goldberg AN, Pletcher SD, Seibold MA, Moore CM, Gordon ED. IL-13-associated epithelial remodeling correlates with clinical severity in nasal polyposis. J Allergy Clin Immunol. 2023 05; 151(5):1277-1285.

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Ma C, Hoffmann FW, Nunes LG, Urena F, Andrukhiv A, Gerschenson M, Pitts MW, Hoffmann PR. Selenoprotein I deficiency in T cells promotes differentiation into tolerant phenotypes while decreasing Th17 pathology. J Leukoc Biol. 2022 12; 112(6):1387-1397.

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Ban Y, Dong W, Zhang L, Zhou T, Altiti AS, Ali K, Mootoo DR, Blaho VA, Hla T, Ren Y, Ma X. Abrogation of Endogenous Glycolipid Antigen Presentation on Myelin-Laden Macrophages by D-Sphingosine Ameliorates the Pathogenesis of Experimental Autoimmune Encephalomyelitis. Front Immunol. 2019; 10:404.

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Mebratu YA, Tesfaigzi Y. IL-17 Plays a Role in Respiratory Syncytial Virus-induced Lung Inflammation and Emphysema in Elastase and LPS-injured Mice. Am J Respir Cell Mol Biol. 2018 06; 58(6):717-726.

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Forno E, Sordillo J, Brehm J, Chen W, Benos T, Yan Q, Avila L, Soto-Quir?s M, Cloutier MM, Col?n-Semidey A, Alvarez M, Acosta-P?rez E, Weiss ST, Litonjua AA, Canino G, Celed?n JC. Genome-wide interaction study of dust mite allergen on lung function in children with asthma. J Allergy Clin Immunol. 2017 Oct; 140(4):996-1003.e7.

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Cunningham AL, Guentzel MN, Yu JJ, Hung CY, Forsthuber TG, Navara CS, Yagita H, Williams IR, Klose KE, Eaves-Pyles TD, Arulanandam BP. M-Cells Contribute to the Entry of an Oral Vaccine but Are Not Essential for the Subsequent Induction of Protective Immunity against Francisella tularensis. PLoS One. 2016; 11(4):e0153402.

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Hung CY, Castro-Lopez N, Cole GT. Card9- and MyD88-Mediated Gamma Interferon and Nitric Oxide Production Is Essential for Resistance to Subcutaneous Coccidioides posadasii Infection. Infect Immun. 2016 Apr; 84(4):1166-75.

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Liu S, Zhang Q, Chen C, Ge D, Qu Y, Chen R, Fan YM, Li N, Tang WW, Zhang W, Zhang K, Wang AR, Rowan BG, Hill SM, Sartor O, Abdel-Mageed AB, Myers L, Lin Q, You Z. Hyperinsulinemia enhances interleukin-17-induced inflammation to promote prostate cancer development in obese mice through inhibiting glycogen synthase kinase 3-mediated phosphorylation and degradation of interleukin-17 receptor. Oncotarget. 2016 Mar 22; 7(12):13651-66.

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Matsuzaki H, Mikami Y, Makita K, Takeshima H, Horie M, Noguchi S, Jo T, Narumoto O, Kohyama T, Takizawa H, Nagase T, Yamauchi Y. Interleukin-17A and Toll-Like Receptor 3 Ligand Poly(I:C) Synergistically Induced Neutrophil Chemoattractant Production by Bronchial Epithelial Cells. PLoS One. 2015; 10(10):e0141746.

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