Interleukin-10

"Interleukin-10" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A cytokine produced by a variety of cell types, including T-LYMPHOCYTES; MONOCYTES; DENDRITIC CELLS; and EPITHELIAL CELLS that exerts a variety of effects on immunoregulation and INFLAMMATION. Interleukin-10 combines with itself to form a homodimeric molecule that is the biologically active form of the protein.

Descriptor ID	D016753
MeSH Number(s)	D12.644.276.374.465.510 D12.776.467.374.465.510 D23.529.374.465.510
Concept/Terms	Interleukin-10 Interleukin-10 Interleukin 10 IL10 IL-10 CSIF-10 Cytokine Synthesis Inhibitory Factor

Below are MeSH descriptors whose meaning is more general than "Interleukin-10".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intercellular Signaling Peptides and Proteins [D12.644.276]
Cytokines [D12.644.276.374]
Interleukins [D12.644.276.374.465]
Interleukin-10 [D12.644.276.374.465.510]
Proteins [D12.776]
Intercellular Signaling Peptides and Proteins [D12.776.467]
Cytokines [D12.776.467.374]
Interleukins [D12.776.467.374.465]
Interleukin-10 [D12.776.467.374.465.510]
Biological Factors [D23]
Intercellular Signaling Peptides and Proteins [D23.529]
Cytokines [D23.529.374]
Interleukins [D23.529.374.465]
Interleukin-10 [D23.529.374.465.510]

Below are MeSH descriptors whose meaning is related to "Interleukin-10".

Below are MeSH descriptors whose meaning is more specific than "Interleukin-10".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Interleukin-10" by people in this website by year, and whether "Interleukin-10" was a major or minor topic of these publications.

Bar chart showing 56 publications over 24 distinct years, with a maximum of 5 publications in 2010

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	0	1	1
1996	1	0	1
1998	0	3	3
1999	1	1	2
2000	0	1	1
2001	0	1	1
2002	1	2	3
2005	2	1	3
2006	1	1	2
2007	1	2	3
2008	1	3	4
2009	2	2	4
2010	2	3	5
2011	1	1	2
2012	1	0	1
2013	3	0	3
2014	0	2	2
2015	2	1	3
2016	1	2	3
2017	0	1	1
2018	0	2	2
2020	1	1	2
2021	2	1	3
2023	0	1	1

Below are the most recent publications written about "Interleukin-10" by people in Profiles.

Sun C, Rahman MSU, Enkhjargal B, Peng J, Zhou K, Xie Z, Wu L, Zhang T, Zhu Q, Tang J, Zeng Y, Zhang JH, Xu S. Osteopontin modulates microglial activation states and attenuates inflammatory responses after subarachnoid hemorrhage in rats. Exp Neurol. 2024 01; 371:114585.

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Atwater AQ, Immergluck LC, Davidson AJ, Castanon-Cervantes O. Shift Work Predicts Increases in Lipopolysaccharide-Binding Protein, Interleukin-10, and Leukocyte Counts in a Cross-Sectional Study of Healthy Volunteers Carrying Low-Grade Systemic Inflammation. Int J Environ Res Public Health. 2021 12 14; 18(24).

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Diorio C, Shraim R, Vella LA, Giles JR, Baxter AE, Oldridge DA, Canna SW, Henrickson SE, McNerney KO, Balamuth F, Burudpakdee C, Lee J, Leng T, Farrel A, Lambert MP, Sullivan KE, Wherry EJ, Teachey DT, Bassiri H, Behrens EM. Proteomic profiling of MIS-C patients indicates heterogeneity relating to interferon gamma dysregulation and vascular endothelial dysfunction. Nat Commun. 2021 12 10; 12(1):7222.

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Chauss D, Freiwald T, McGregor R, Yan B, Wang L, Nova-Lamperti E, Kumar D, Zhang Z, Teague H, West EE, Vannella KM, Ramos-Benitez MJ, Bibby J, Kelly A, Malik A, Freeman AF, Schwartz DM, Portilla D, Chertow DS, John S, Lavender P, Kemper C, Lombardi G, Mehta NN, Cooper N, Lionakis MS, Laurence A, Kazemian M, Afzali B. Autocrine vitamin D signaling switches off pro-inflammatory programs of TH1 cells. Nat Immunol. 2022 01; 23(1):62-74.

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Kurtz JR, Nieves W, Bauer DL, Israel KE, Adcox HE, Gunn JS, Morici LA, McLachlan JB. Salmonella Persistence and Host Immunity Are Dictated by the Anatomical Microenvironment. Infect Immun. 2020 07 21; 88(8).

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Abbas M, Mason T, Ibad A, Khraiwesh M, Apprey V, Kanaan Y, Wilson B, Dunston G, Ricks-Santi L, Brim H. Genetic Polymorphisms in IL-10 Promoter Are Associated With Smoking and Prostate Cancer Risk in African Americans. Anticancer Res. 2020 Jan; 40(1):27-34.

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Lainez NM, Jonak CR, Nair MG, Ethell IM, Wilson EH, Carson MJ, Coss D. Diet-Induced Obesity Elicits Macrophage Infiltration and Reduction in Spine Density in the Hypothalami of Male but Not Female Mice. Front Immunol. 2018; 9:1992.

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Wilson KD, Ochoa LF, Solomon OD, Pal R, Cardona SM, Carpio VH, Keiser PH, Cardona AE, Vargas G, Stephens R. Elimination of intravascular thrombi prevents early mortality and reduces gliosis in hyper-inflammatory experimental cerebral malaria. J Neuroinflammation. 2018 Jun 04; 15(1):173.

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Ryans K, Omosun Y, McKeithen DN, Simoneaux T, Mills CC, Bowen N, Eko FO, Black CM, Igietseme JU, He Q. The immunoregulatory role of alpha enolase in dendritic cell function during Chlamydia infection. BMC Immunol. 2017 05 19; 18(1):27.

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Sharma A, Sharma P, Vishwakarma AL, Srivastava M. Functional Impairment of Murine Dendritic Cell Subsets following Infection with Infective Larval Stage 3 of Brugia malayi. Infect Immun. 2017 Jan; 85(1).

View in: PubMed

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