Interleukin-6

"Interleukin-6" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A cytokine that stimulates the growth and differentiation of B-LYMPHOCYTES and is also a growth factor for HYBRIDOMAS and plasmacytomas. It is produced by many different cells including T-LYMPHOCYTES; MONOCYTES; and FIBROBLASTS.

Descriptor ID	D015850
MeSH Number(s)	D12.644.276.374.465.224 D12.776.467.374.465.202 D23.529.374.465.224
Concept/Terms	Interleukin-6 Interleukin-6 Interleukin 6 IL6 B-Cell Stimulatory Factor 2 B-Cell Stimulatory Factor-2 Differentiation Factor-2, B-Cell Differentiation Factor 2, B Cell B-Cell Differentiation Factor-2 B Cell Differentiation Factor 2 BSF-2 Hybridoma Growth Factor Growth Factor, Hybridoma IFN-beta 2 Plasmacytoma Growth Factor Growth Factor, Plasmacytoma Hepatocyte-Stimulating Factor Hepatocyte Stimulating Factor MGI-2 Myeloid Differentiation-Inducing Protein Differentiation-Inducing Protein, Myeloid Myeloid Differentiation Inducing Protein B-Cell Differentiation Factor B Cell Differentiation Factor Differentiation Factor, B-Cell Differentiation Factor, B Cell IL-6 Interferon beta-2 Interferon beta 2 beta-2, Interferon B Cell Stimulatory Factor-2 B Cell Stimulatory Factor 2

Below are MeSH descriptors whose meaning is more general than "Interleukin-6".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intercellular Signaling Peptides and Proteins [D12.644.276]
Cytokines [D12.644.276.374]
Interleukins [D12.644.276.374.465]
Interleukin-6 [D12.644.276.374.465.224]
Proteins [D12.776]
Intercellular Signaling Peptides and Proteins [D12.776.467]
Cytokines [D12.776.467.374]
Interleukins [D12.776.467.374.465]
Interleukin-6 [D12.776.467.374.465.202]
Biological Factors [D23]
Intercellular Signaling Peptides and Proteins [D23.529]
Cytokines [D23.529.374]
Interleukins [D23.529.374.465]
Interleukin-6 [D23.529.374.465.224]

Below are MeSH descriptors whose meaning is related to "Interleukin-6".

Below are MeSH descriptors whose meaning is more specific than "Interleukin-6".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Interleukin-6" by people in this website by year, and whether "Interleukin-6" was a major or minor topic of these publications.

Bar chart showing 126 publications over 30 distinct years, with a maximum of 9 publications in 2012 and 2014

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	2	2	4
1996	1	0	1
1997	2	0	2
1998	1	2	3
1999	0	2	2
2000	1	0	1
2001	2	1	3
2002	1	2	3
2003	0	2	2
2004	1	1	2
2005	0	2	2
2006	1	5	6
2007	2	5	7
2008	3	2	5
2009	3	3	6
2010	2	5	7
2011	3	5	8
2012	6	3	9
2013	4	4	8
2014	2	7	9
2015	0	6	6
2016	0	5	5
2017	2	3	5
2018	1	1	2
2019	0	4	4
2020	0	1	1
2021	2	1	3
2022	0	5	5
2023	2	1	3
2024	0	2	2

Below are the most recent publications written about "Interleukin-6" by people in Profiles.

Kim M, McCann JJ, Fortner J, Randall E, Chen C, Chen Y, Yaari Z, Wang Y, Koder RL, Heller DA. Quantum Defect Sensitization via Phase-Changing Supercharged Antibody Fragments. J Am Chem Soc. 2024 May 08; 146(18):12454-12462.

View in: PubMed
Ouhara K, Takemura T, Taniguchi Y, Fujimori R, Tamura T, Akane Y, Matsuda S, Hamamoto Y, Shintani T, Kajiya M, Munenaga S, Iwata T, Fujita T, Mizuno N. Leucine-rich alpha-2-glycoprotein 1 affects bone destruction via IL-6 in mouse periodontitis model. Oral Dis. 2024 Nov; 30(8):5294-5304.

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Zhu HT, Luo J, Peng Y, Cheng XF, Wu SZ, Zhao YD, Chang L, Sun ZJ, Dong DL. Nitazoxanide protects against experimental ulcerative colitis through improving intestinal barrier and inhibiting inflammation. Chem Biol Interact. 2024 May 25; 395:111013.

View in: PubMed
Zhu N, Mealka M, Mitchel S, Milani C, Acu?a LM, Rogers E, Lahana AN, Huxford T. X-ray Crystallographic Study of Preferred Spacing by the NF-?B p50 Homodimer on ?B DNA. Biomolecules. 2023 08 26; 13(9).

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Inoue Y, Inui N, Karayama M, Asada K, Fujii M, Matsuura S, Uto T, Hashimoto D, Matsui T, Ikeda M, Yasui H, Hozumi H, Suzuki Y, Furuhashi K, Enomoto N, Fujisawa T, Suda T. Cytokine profiling identifies circulating IL-6 and IL-15 as prognostic stratifiers in patients with non-small cell lung cancer receiving anti-PD-1/PD-L1 blockade therapy. Cancer Immunol Immunother. 2023 Aug; 72(8):2717-2728.

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Dabiri S, Ram?rez Ruiz MI, Jean-Louis G, Ntekim OE, Obisesan TO, Campbell AL, Mwendwa DT. The Mediating Role of Inflammation in the Relationship Between a-Synuclein and Cognitive Functioning. J Gerontol A Biol Sci Med Sci. 2023 02 24; 78(2):206-212.

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Hernandez J, Tamargo JA, Sales Martinez S, Martin HR, Campa A, S?kaly RP, Bordi R, Sherman KE, Rouster SD, Meeds HL, Khalsa JH, Mandler RN, Lai S, Baum MK. Cocaine use associated gut permeability and microbial translocation in people living with HIV in the Miami Adult Study on HIV (MASH) cohort. PLoS One. 2022; 17(10):e0275675.

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Geagea L, Ghanim? PM, El Hayek S, Kobeissy F, Tamim H, Elbejjani M, Talih F. Assessing cognitive behavioral therapy for insomnia in individuals with cannabis use disorder utilizing actigraphy and serum biomarkers: A pilot study. Sleep Med. 2022 12; 100:434-441.

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Ghanooni D, Carrico AW, Williams R, Glynn TR, Moskowitz JT, Pahwa S, Pallikkuth S, Roach ME, Dilworth S, Aouizerat BE, Flentje A. Sexual Minority Stress and Cellular Aging in Methamphetamine-Using Sexual Minority Men With Treated HIV. Psychosom Med. 2022 10 01; 84(8):949-956.

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Roy S, Bhowmik DR, Begum R, Amin MT, Islam MA, Ahmed F, Hossain MS. Aspirin attenuates the expression of adhesion molecules, risk of obesity, and adipose tissue inflammation in high-fat diet-induced obese mice. Prostaglandins Other Lipid Mediat. 2022 10; 162:106664.

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