Nerve Degeneration

"Nerve Degeneration" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.

Descriptor ID	D009410
MeSH Number(s)	C23.550.737
Concept/Terms	Nerve Degeneration Nerve Degeneration Degeneration, Nerve Degenerations, Nerve Nerve Degenerations Neuron Degeneration Degeneration, Neuron Degenerations, Neuron Neuron Degenerations

Below are MeSH descriptors whose meaning is more general than "Nerve Degeneration".

Diseases [C]
Pathological Conditions, Signs and Symptoms [C23]
Pathologic Processes [C23.550]
Nerve Degeneration [C23.550.737]

Below are MeSH descriptors whose meaning is related to "Nerve Degeneration".

Below are MeSH descriptors whose meaning is more specific than "Nerve Degeneration".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Nerve Degeneration" by people in this website by year, and whether "Nerve Degeneration" was a major or minor topic of these publications.

Bar chart showing 85 publications over 23 distinct years, with a maximum of 9 publications in 2009

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	1	2	3
1995	0	2	2
1998	0	2	2
1999	0	2	2
2001	0	3	3
2002	1	1	2
2003	4	3	7
2004	4	4	8
2005	6	2	8
2006	6	1	7
2007	2	3	5
2008	2	1	3
2009	3	6	9
2010	0	3	3
2011	1	1	2
2012	1	0	1
2013	1	1	2
2015	1	0	1
2017	1	1	2
2018	3	3	6
2019	2	1	3
2020	1	0	1
2021	2	1	3

Below are the most recent publications written about "Nerve Degeneration" by people in Profiles.

Parodi-Rull?n RM, Javadov S, Fossati S. Dissecting the Crosstalk between Endothelial Mitochondrial Damage, Vascular Inflammation, and Neurodegeneration in Cerebral Amyloid Angiopathy and Alzheimer's Disease. Cells. 2021 10 27; 10(11).

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Tinkov AA, Martins AC, Avila DS, Gritsenko VA, Skalny AV, Santamaria A, Lee E, Bowman AB, Aschner M. Gut Microbiota as a Potential Player in Mn-Induced Neurotoxicity. Biomolecules. 2021 08 31; 11(9).

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Mendelowitz ZZ, Idrizi A, Mano I. Live Animal Imaging and Cell Sorting Methods for Investigating Neurodegeneration in a C. elegans Excitotoxic Necrosis Model. J Vis Exp. 2021 01 22; (167).

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Kobrina A, Schrode KM, Screven LA, Javaid H, Weinberg MM, Brown G, Board R, Villavisanis DF, Dent ML, Lauer AM. Linking anatomical and physiological markers of auditory system degeneration with behavioral hearing assessments in a mouse (Mus musculus) model of age-related hearing loss. Neurobiol Aging. 2020 12; 96:87-103.

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Kavetsky L, Green KK, Boyle BR, Yousufzai FAK, Padron ZM, Melli SE, Kuhnel VL, Jackson HM, Blanco RE, Howell GR, Soto I. Increased interactions and engulfment of dendrites by microglia precede Purkinje cell degeneration in a mouse model of Niemann Pick Type-C. Sci Rep. 2019 10 11; 9(1):14722.

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Hsieh YC, Guo C, Yalamanchili HK, Abreha M, Al-Ouran R, Li Y, Dammer EB, Lah JJ, Levey AI, Bennett DA, De Jager PL, Seyfried NT, Liu Z, Shulman JM. Tau-Mediated Disruption of the Spliceosome Triggers Cryptic RNA Splicing and Neurodegeneration in Alzheimer's Disease. Cell Rep. 2019 10 08; 29(2):301-316.e10.

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Chen YC, Ma NX, Pei ZF, Wu Z, Do-Monte FH, Keefe S, Yellin E, Chen MS, Yin JC, Lee G, Minier-Toribio A, Hu Y, Bai YT, Lee K, Quirk GJ, Chen G. A NeuroD1 AAV-Based Gene Therapy for Functional Brain Repair after Ischemic Injury through In?Vivo Astrocyte-to-Neuron Conversion. Mol Ther. 2020 01 08; 28(1):217-234.

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Feldmann KG, Chowdhury A, Becker JL, McAlpin N, Ahmed T, Haider S, Richard Xia JX, Diaz K, Mehta MG, Mano I. Non-canonical activation of CREB mediates neuroprotection in a Caenorhabditis elegans model of excitotoxic necrosis. J Neurochem. 2019 02; 148(4):531-549.

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Gallea JI, Ambroggio EE, Vilcaes AA, James NG, Jameson DM, Celej MS. Amyloid oligomerization of the Parkinson's disease related protein a-synuclein impacts on its curvature-membrane sensitivity. J Neurochem. 2018 11; 147(4):541-556.

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Paley EL, Perry G. Towards an Integrative Understanding of tRNA Aminoacylation-Diet-Host-Gut Microbiome Interactions in Neurodegeneration. Nutrients. 2018 Mar 26; 10(4).

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