"Cyclic GMP" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Guanosine cyclic 3',5'-(hydrogen phosphate). A guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the 3'- and 5'-positions. It is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones, including acetylcholine, insulin, and oxytocin and it has been found to activate specific protein kinases. (From Merck Index, 11th ed)
| Descriptor ID |
D006152
|
| MeSH Number(s) |
D03.633.100.759.646.454.160 D13.695.462.275 D13.695.667.454.160 D13.695.827.426.160
|
| Concept/Terms |
Cyclic GMP- Cyclic GMP
- GMP, Cyclic
- Guanosine Cyclic Monophosphate
- Cyclic Monophosphate, Guanosine
- Monophosphate, Guanosine Cyclic
- Guanosine Cyclic 3',5'-Monophosphate
- 3',5'-Monophosphate, Guanosine Cyclic
- Cyclic 3',5'-Monophosphate, Guanosine
- Guanosine Cyclic 3,5 Monophosphate
- Guanosine Cyclic-3',5'-Monophosphate
- Cyclic-3',5'-Monophosphate, Guanosine
- Guanosine Cyclic 3',5' Monophosphate
|
Below are MeSH descriptors whose meaning is more general than "Cyclic GMP".
Below are MeSH descriptors whose meaning is more specific than "Cyclic GMP".
This graph shows the total number of publications written about "Cyclic GMP" by people in this website by year, and whether "Cyclic GMP" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2000 | 0 | 3 | 3 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 4 | 4 |
| 2003 | 0 | 3 | 3 |
| 2004 | 1 | 2 | 3 |
| 2005 | 0 | 2 | 2 |
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 2 | 3 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 2 | 2 |
| 2011 | 0 | 1 | 1 |
| 2012 | 2 | 2 | 4 |
| 2013 | 0 | 2 | 2 |
| 2015 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 0 | 2 | 2 |
| 2019 | 1 | 1 | 2 |
| 2020 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
| 2025 | 1 | 1 | 2 |
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click here.
Below are the most recent publications written about "Cyclic GMP" by people in Profiles.
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Baskaran P, Aldhaeefi M, Asaadi A, Jones M, King E, Rungkitwattanakul D, Wingate L. Empagliflozin and hydralazine-isosorbide dinitrate combination therapy improves outcomes in Black patients with heart failure. Int J Clin Pharmacol Ther. 2025 Nov; 63(11):553-556.
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Ferrini MG, Abraham A, Mill?n R, Graciano L, Eleswarapu SV, Rajfer J. Nutraceutical COMP-4 confers protection against endothelial dysfunction through the eNOS/iNOS-NO-cGMP pathway. PLoS One. 2025; 20(2):e0316798.
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Bahadoran Z, Mirmiran P, Kashfi K, Ghasemi A. Vascular nitric oxide resistance in type 2 diabetes. Cell Death Dis. 2023 07 11; 14(7):410.
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Ghose R. Keep a lid on it: A troika in kinase allostery. J Biol Chem. 2020 06 19; 295(25):8492-8493.
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Kitts G, Giglio KM, Zamorano-S?nchez D, Park JH, Townsley L, Cooley RB, Wucher BR, Klose KE, Nadell CD, Yildiz FH, Sondermann H. A Conserved Regulatory Circuit Controls Large Adhesins in Vibrio cholerae. mBio. 2019 12 03; 10(6).
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Ferrini MG, Abraham A, Nguyen S, Luna R, Flores M, Artaza JN, Graciano L, Rajfer J. Exogenous l-ARGININE does not stimulate production OF NO or cGMP within the rat corporal smooth muscle cells in culture. Nitric Oxide. 2019 08 01; 89:64-70.
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Gonzalez-Cadavid NF, Rajfer J. The two phases of the clinical validation of preclinical translational mechanistic research on PDE5 inhibitors since Viagra's advent. A personal perspective. Int J Impot Res. 2019 Mar; 31(2):57-60.
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Ferrini MG, Garcia E, Abraham A, Artaza JN, Nguyen S, Rajfer J. Effect of ginger, Paullinia cupana, muira puama and l- citrulline, singly or in combination, on modulation of the inducible nitric oxide- NO-cGMP pathway in rat penile smooth muscle cells. Nitric Oxide. 2018 Jun 01; 76:81-86.
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Mewborn L, Benitez JA, Silva AJ. Flagellar motility, extracellular proteases and Vibrio cholerae detachment from abiotic and biotic surfaces. Microb Pathog. 2017 Dec; 113:17-24.
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Simmons DV, Petko AK, Paladini CA. Differential expression of long-term potentiation among identified inhibitory inputs to dopamine neurons. J Neurophysiol. 2017 10 01; 118(4):1998-2008.