Guanylyl Imidodiphosphate
"Guanylyl Imidodiphosphate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A non-hydrolyzable analog of GTP, in which the oxygen atom bridging the beta to the gamma phosphate is replaced by a nitrogen atom. It binds tightly to G-protein in the presence of Mg2+. The nucleotide is a potent stimulator of ADENYLYL CYCLASES.
| Descriptor ID |
D006165
|
| MeSH Number(s) |
D03.633.100.759.646.454.504.400 D13.695.667.454.504.400 D13.695.827.426.504.400
|
| Concept/Terms |
Guanylyl Imidodiphosphate- Guanylyl Imidodiphosphate
- Imidodiphosphate, Guanylyl
- Guanosine 5'-(Beta,Gamma-Imido)Triphosphate
- Guanyl-5'-Imidodiphosphate
- Guanyl 5' Imidodiphosphate
- GMP-PNP
- P(NH)PPG
- GMP-P(NH)P
- Gpp(NH)p
|
Below are MeSH descriptors whose meaning is more general than "Guanylyl Imidodiphosphate".
Below are MeSH descriptors whose meaning is more specific than "Guanylyl Imidodiphosphate".
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Below are the most recent publications written about "Guanylyl Imidodiphosphate" by people in Profiles.
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Graham SM, Arinze IJ. High and low affinity sites associated with the binding of [3H]guanyl-5'-yl imidodiphosphate to liver plasma membranes. Res Commun Chem Pathol Pharmacol. 1987 Jun; 56(3):301-20.
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Kawai Y, Graham SM, Yoshioka H, Arinze IJ. Beta-adrenergic receptors in guinea-pig liver plasma membranes and thermal lability of [3H]dihydroalprenolol binding sites. Biochem Pharmacol. 1986 Dec 15; 35(24):4387-93.
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Kawai Y, Powell A, Arinze IJ. Adrenergic receptors in human liver plasma membranes: predominance of beta 2- and alpha 1-receptor subtypes. J Clin Endocrinol Metab. 1986 May; 62(5):827-32.
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Banerjee DK, Baksi K, Friedman RM. Interferon-mediated inhibition of adenylate cyclase in mouse cells. J Interferon Res. 1982; 2(4):501-10.
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Treistman SN. Effect of adenosine 3',5'-monophosphate on neuronal pacemaker activity: a voltage clamp analysis. Science. 1981 Jan 02; 211(4477):59-61.
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Drake PF, Treistman SN. Alteration of neuronal activity in response to cyclic nucleotide agents in Aplysia. J Neurobiol. 1980 Sep; 11(5):471-82.
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Treistman SN, Drake PF. The effects of cyclic nucleotide agents on neurons in Aplysia. Brain Res. 1979 Jun 08; 168(3):643-7.