Cyclic AMP

"Cyclic AMP" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

An adenine nucleotide containing one phosphate group which is esterified to both the 3'- and 5'-positions of the sugar moiety. It is a second messenger and a key intracellular regulator, functioning as a mediator of activity for a number of hormones, including epinephrine, glucagon, and ACTH.

Descriptor ID	D000242
MeSH Number(s)	D03.633.100.759.646.138.395 D13.695.462.200 D13.695.667.138.395 D13.695.827.068.395
Concept/Terms	Cyclic AMP Cyclic AMP AMP, Cyclic Adenosine Cyclic-3',5'-Monophosphate Cyclic-3',5'-Monophosphate, Adenosine Adenosine Cyclic Monophosphate Cyclic Monophosphate, Adenosine Monophosphate, Adenosine Cyclic Adenosine Cyclic 3,5 Monophosphate Adenosine Cyclic 3',5'-Monophosphate 3',5'-Monophosphate, Adenosine Cyclic Adenosine Cyclic 3',5' Monophosphate Cyclic 3',5'-Monophosphate, Adenosine Cyclic AMP, Monosodium Salt Cyclic AMP, Monosodium Salt Cyclic AMP, Sodium Salt Cyclic AMP, Sodium Salt Cyclic AMP, Monoammonium Salt Cyclic AMP, Monoammonium Salt Cyclic AMP, (R)-Isomer Cyclic AMP, (R)-Isomer Cyclic AMP, Disodium Salt Cyclic AMP, Disodium Salt Cyclic AMP, Monopotassium Salt Cyclic AMP, Monopotassium Salt

Below are MeSH descriptors whose meaning is more general than "Cyclic AMP".

Chemicals and Drugs [D]
Heterocyclic Compounds [D03]
Heterocyclic Compounds, Fused-Ring [D03.633]
Heterocyclic Compounds, 2-Ring [D03.633.100]
Purines [D03.633.100.759]
Purine Nucleotides [D03.633.100.759.646]
Adenine Nucleotides [D03.633.100.759.646.138]
Cyclic AMP [D03.633.100.759.646.138.395]
Nucleic Acids, Nucleotides, and Nucleosides [D13]
Nucleotides [D13.695]
Nucleotides, Cyclic [D13.695.462]
Cyclic AMP [D13.695.462.200]
Purine Nucleotides [D13.695.667]
Adenine Nucleotides [D13.695.667.138]
Cyclic AMP [D13.695.667.138.395]
Ribonucleotides [D13.695.827]
Adenine Nucleotides [D13.695.827.068]
Cyclic AMP [D13.695.827.068.395]

Below are MeSH descriptors whose meaning is related to "Cyclic AMP".

Below are MeSH descriptors whose meaning is more specific than "Cyclic AMP".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Cyclic AMP" by people in this website by year, and whether "Cyclic AMP" was a major or minor topic of these publications.

Bar chart showing 96 publications over 27 distinct years, with a maximum of 6 publications in 1997 and 2003 and 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	0	2	2
1997	4	2	6
1998	3	2	5
1999	2	3	5
2000	0	3	3
2001	0	5	5
2002	1	4	5
2003	3	3	6
2004	2	2	4
2005	0	4	4
2006	3	0	3
2007	2	0	2
2008	1	4	5
2009	1	2	3
2010	2	3	5
2011	0	2	2
2012	2	2	4
2013	3	3	6
2014	0	1	1
2015	2	1	3
2016	0	4	4
2017	0	5	5
2019	0	2	2
2020	0	1	1
2021	0	2	2
2022	1	1	2
2023	0	1	1

Below are the most recent publications written about "Cyclic AMP" by people in Profiles.

Slika H, Mansour H, Nasser SA, Shaito A, Kobeissy F, Orekhov AN, Pintus G, Eid AH. Epac as a tractable therapeutic target. Eur J Pharmacol. 2023 Apr 15; 945:175645.

View in: PubMed
Yu S, Doycheva DM, Gamdzyk M, Gao Y, Guo Y, Travis ZD, Tang J, Chen WX, Zhang JH. BMS-470539 Attenuates Oxidative Stress and Neuronal Apoptosis via MC1R/cAMP/PKA/Nurr1 Signaling Pathway in a Neonatal Hypoxic-Ischemic Rat Model. Oxid Med Cell Longev. 2022; 2022:4054938.

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Brazill D, Knecht DA. Chemotaxis: Under Agarose Assay. Methods Mol Biol. 2022; 2364:327-338.

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Zhang S, Wang H, Melick CH, Jeong MH, Curukovic A, Tiwary S, Lama-Sherpa TD, Meng D, Servage KA, James NG, Jewell JL. AKAP13 couples GPCR signaling to mTORC1 inhibition. PLoS Genet. 2021 10; 17(10):e1009832.

View in: PubMed
Matsui T. Exhaustive endurance exercise activates brain glycogen breakdown and lactate production more than insulin-induced hypoglycemia. Am J Physiol Regul Integr Comp Physiol. 2021 04 01; 320(4):R500-R507.

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Lin PH, Kuo TH, Chen CC, Jian CY, Chen CW, Wang KL, Kuo YC, Shen HY, Hsia SM, Wang PS, Lieu FK, Wang SW. Downregulation of testosterone production through luteinizing hormone receptor regulation in male rats exposed to 17a-ethynylestradiol. Sci Rep. 2020 01 31; 10(1):1576.

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S?nchez-Breta?o A, Suen TC, Baba K, DeBruyne J, Tosini G. Melatonin receptor heterodimerization in a photoreceptor-like cell line endogenously expressing melatonin receptors. Mol Vis. 2019; 25:791-799.

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Zuo G, Zhang T, Huang L, Araujo C, Peng J, Travis Z, Okada T, Ocak U, Zhang G, Tang J, Lu X, Zhang JH. Activation of TGR5 with INT-777 attenuates oxidative stress and neuronal apoptosis via cAMP/PKCe/ALDH2 pathway after subarachnoid hemorrhage in rats. Free Radic Biol Med. 2019 11 01; 143:441-453.

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Zhang QH, Hao JW, Li GL, Ji XJ, Yao XD, Dong N, Yao YM. Proinflammatory switch from Gas to Gai signaling by Glucagon-like peptide-1 receptor in murine splenic monocyte following burn injury. Inflamm Res. 2018 Feb; 67(2):157-168.

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Toussaint J, Raval CB, Nguyen T, Fadaifard H, Joshi S, Wolberg G, Quarfordt S, Jan KM, Rumschitzki DS. Chronic hypertension increases aortic endothelial hydraulic conductivity by upregulating endothelial aquaporin-1 expression. Am J Physiol Heart Circ Physiol. 2017 Nov 01; 313(5):H1063-H1073.

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