Nitric Oxide Synthase Type II
"Nitric Oxide Synthase Type II" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A CALCIUM-independent subtype of nitric oxide synthase that may play a role in immune function. It is an inducible enzyme whose expression is transcriptionally regulated by a variety of CYTOKINES.
| Descriptor ID |
D052247
|
| MeSH Number(s) |
D08.811.682.664.500.772.500 D12.776.157.687.575 D12.776.660.720.575
|
| Concept/Terms |
Nitric Oxide Synthase Type II- Nitric Oxide Synthase Type II
- Inducible NOS Protein
- NOS-II
- NOS II
- Nitric Oxide Synthase II
- Nitric Oxide Synthase, Type II
- Inducible Nitric Oxide Synthase
- INOS Enzyme
|
Below are MeSH descriptors whose meaning is more general than "Nitric Oxide Synthase Type II".
Below are MeSH descriptors whose meaning is more specific than "Nitric Oxide Synthase Type II".
This graph shows the total number of publications written about "Nitric Oxide Synthase Type II" by people in this website by year, and whether "Nitric Oxide Synthase Type II" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 4 | 4 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 2 | 2 |
| 2001 | 0 | 4 | 4 |
| 2002 | 0 | 6 | 6 |
| 2003 | 0 | 7 | 7 |
| 2004 | 0 | 3 | 3 |
| 2005 | 1 | 5 | 6 |
| 2006 | 2 | 1 | 3 |
| 2007 | 0 | 2 | 2 |
| 2008 | 1 | 4 | 5 |
| 2010 | 0 | 2 | 2 |
| 2011 | 3 | 1 | 4 |
| 2012 | 2 | 0 | 2 |
| 2013 | 1 | 0 | 1 |
| 2014 | 1 | 3 | 4 |
| 2015 | 1 | 3 | 4 |
| 2016 | 1 | 1 | 2 |
| 2017 | 0 | 2 | 2 |
| 2018 | 0 | 7 | 7 |
| 2019 | 1 | 2 | 3 |
| 2020 | 0 | 4 | 4 |
| 2021 | 1 | 1 | 2 |
| 2024 | 0 | 1 | 1 |
| 2025 | 3 | 0 | 3 |
To return to the timeline,
click here.
Below are the most recent publications written about "Nitric Oxide Synthase Type II" by people in Profiles.
-
Armina-Rodriguez A, Vald?s Fernandez BN, Ocasio-Malav? C, Cantres Rosario YM, Carrasquillo Carri?n K, Mel?ndez LM, Roche Lima A, Tosado Rodriguez EL, Espino AM. Quantitative Proteomics Reveals Fh15 as an Antagonist of TLR4 Downregulating the Activation of NF-?B, Inducible Nitric Oxide, Phagosome Signaling Pathways, and Oxidative Stress of LPS-Stimulated Macrophages. Int J Mol Sci. 2025 Jul 18; 26(14).
-
Farahani A, Farahani A, Kashfi K, Ghasemi A. Inducible nitric oxide synthase (iNOS): More than an inducible enzyme? Rethinking the classification of NOS isoforms. Pharmacol Res. 2025 Jun; 216:107781.
-
Ferrini MG, Abraham A, Mill?n R, Graciano L, Eleswarapu SV, Rajfer J. Nutraceutical COMP-4 confers protection against endothelial dysfunction through the eNOS/iNOS-NO-cGMP pathway. PLoS One. 2025; 20(2):e0316798.
-
Zhu HT, Luo J, Peng Y, Cheng XF, Wu SZ, Zhao YD, Chang L, Sun ZJ, Dong DL. Nitazoxanide protects against experimental ulcerative colitis through improving intestinal barrier and inhibiting inflammation. Chem Biol Interact. 2024 May 25; 395:111013.
-
Xu M, Lantz MJ, Nichols RA, Li QX. Anti-Neuroinflammatory Effects of a Semi-Synthetic Isoorientin-Based Glycogen Synthase Kinase-3? Inhibitor in Lipopolysaccharide-Activated Microglial Cells. ACS Chem Neurosci. 2022 01 05; 13(1):43-52.
-
Kashfi K, Kannikal J, Nath N. Macrophage Reprogramming and Cancer Therapeutics: Role of iNOS-Derived NO. Cells. 2021 11 16; 10(11).
-
Jeddi S, Gheibi S, Kashfi K, Carlstr?m M, Ghasemi A. Protective effect of intermediate doses of hydrogen sulfide against myocardial ischemia-reperfusion injury in obese type 2 diabetic rats. Life Sci. 2020 Sep 01; 256:117855.
-
Kashfi K. Nitric oxide in cancer and beyond. Biochem Pharmacol. 2020 06; 176:114006.
-
Nath N, Kashfi K. Tumor associated macrophages and 'NO'. Biochem Pharmacol. 2020 06; 176:113899.
-
Chattopadhyay M, Kodela R, Santiago G, Le TTC, Nath N, Kashfi K. NOSH-aspirin (NBS-1120) inhibits pancreatic cancer cell growth in a xenograft mouse model: Modulation of FoxM1, p53, NF-?B, iNOS, caspase-3 and ROS. Biochem Pharmacol. 2020 06; 176:113857.