JTT-705 blocks cell proliferation and angiogenesis through p38 kinase/p27(kip1) and Ras/p21(waf1) pathways.

Miura S, Matsuo Y, Kawamura A, Saku K. JTT-705 blocks cell proliferation and angiogenesis through p38 kinase/p27(kip1) and Ras/p21(waf1) pathways. Atherosclerosis. 2005 Oct; 182(2):267-75.

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subject areas

Amides
Atherosclerosis
Cell Division
Cells, Cultured
Coronary Vessels
Cyclin-Dependent Kinase Inhibitor p21
Cyclin-Dependent Kinase Inhibitor p27
Endothelium, Vascular
Enzyme Inhibitors
Esters
Extracellular Signal-Regulated MAP Kinases
Flavonoids
Humans
Imidazoles
Intracellular Signaling Peptides and Proteins
JNK Mitogen-Activated Protein Kinases
MAP Kinase Signaling System
Muscle, Smooth, Vascular
Neovascularization, Pathologic
p38 Mitogen-Activated Protein Kinases
Pyridines
ras Proteins
Sulfhydryl Compounds
Up-Regulation
Vascular Endothelial Growth Factor A

authors with profiles

Akira Kawamura

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